SÜKSİNİK ASİT (SUCCINIC ACID, succinic acid)

Güneş koruyucusuna ek olarak hücresel düzeyde canlanmanın ise en yeni yolu süksinik asit ile mezoterapi uygulaması. Bugüne kadar bize en büyük yardımcı cilt içi hyaluronikasit uygulamaları iken artık süksinikasit ile birlikte tedaviler çok daha güçlü bir hale gelmektedir. hyaluronikasit cilde yoğun nem sağlarken Süksinik asit ciltte 3 ana yaşlanma basamağına etki eder. Cilt metabolizmasını düzenler, antioksidan sistemini destekleyerek hücrelerin güçlenmesine yardımcı olur. Süksinik asit ve hyaluronikasit ile yapılan tedavinin ismi ise redermalizasyondur. Cildinde matlık, kuruluk, ince kırışıklık olan, lekeleri bulunan kişilere uygulama yapılabilir. Uygulama öncesi mutlaka doktor muayenesi önemlidir.

en basit mono- ve dikarboksilik asitlerin gibi, zararlı değildir ancak cilt ve gözlere bir tahriş edici olabilir.

Süksinik asit olan ön-madde bazı poliesterlerin ve bazı bir bileşeni alkid reçineleri . 1,4-Bütandiol (BDO), bir ön-madde olarak süksinik kullanılarak sentezlenebilir. Otomotiv ve elektronik endüstrisi ağır konektörler, izolatörleri, jant kapakları, vites kolları ve takviye kirişleri üretmek için BDO güvenmektedir. Süksinik asit de doku mühendisliği uygulamalarında ADPRT biyobozunur polimerlerin bazlar olarak hizmet vermektedir.

Asilasyon süksinik asit ile adlandırılır sükinasyon . Oversuccination birden fazla süksinat, bir alt-tabaka için ekler oluşur.

Süksinik asit de ağrıyla ilgili sorunlara karşı savaşmak için doğal bir çözümdür.

Süksinik asit ayrıca hayvansal dokularda ve ayrıca dünyanın her yerindeki bitkilerde bulunur. İlaç veya ev kullanımı için, kehribardan çıkartılarak elde edilir veya sentetik olarak üretilir. "Süksinik" kelimesi, Latince kökenli olan "succinum" yani "kehribar" demektir.

Süksinik asit faydalarının bir miktarı bilim tarafından açıklanmış olsa da, insanoğlu Kehribar hakkında hala çok az şey bilindiğine inanıyor. Ne de olsa, doğanın henüz açıklanmayan birçok tıbbi harikası var.

Umarım, bir gün insan, bu ilacı analizlerini ve daha iyi bir şekilde nasıl kullanılabileceğine dair anlayışlarını daha ileriye çıkarabilir. O zamana kadar süksinik asidin çeşitli kullanımlarından ve sağlığınızı geliştirmenize yardımcı olabileceği sayısız yoldan yararlanmaya devam edebilirsiniz.

Aslında kehribarın ve Süksinik asitin burada yüzlerce faydalarını sayabiliriz. Ancak buna bir yazı malesef yetmemektedir. Kehribar kolyenin faydalarını başka yazılarımızda da anlatacağız. Kehribar taşını kullanmak için bir çok neden vardır. Burada sadece Süksinik asite bağlı faydalarından bahsettik. Ancak kehribar diş kolyesinin içerisinde şifalı başka yağlarda bulunmaktadır. Ayrıca kehribar kolyenin kendi enerji seviyesi ve elektromanyetik alanı ile de ilgili bir çok faydaları bulunmaktadır. İnsanımız doğal taş takı takmaya alışacaktır umarım o zararlı plastik ve endüstüriyel ürünlerden uzaklaşır ve kendilerine zarar vermekten vazgeçerler ve doğal taş takının özelliklede kehribar kolyenin şifalı yönleriyle karşılaşırlar.

Aslında kehribar taşınıyi insanımız sadece kehribar diş kolyesi olarak bilmektedir. Ancak en çok kullanması gerekenler ise hamilelerdir. bununla ilgili yazıda yazacağız ileride. Kehribar taşı hamilelik döneminde kullanıldığında bebeklerin bağışıklık sistemlerinin daha iyi oluşmasına katkı sağlamaktadır. Hatta bazı doktorlar bebeklerin bağışıklığı için annelere tablet olarak Süksinik asit vermektedirler.

Süksinik asidin Etki Mekanizması

Süksinik asit Kehribarda % 3-8 nispetinde bulunan organik bir bileşik. Diğer reçinelerde, fosilleşmiş ağaçlarda ve ekseri bitkilerde de bulunur. Düşük konsantrasyonlarda biçok hayvanın dokularında yer alıp, ara metabolizma görevini ifa eder.

Süksinik asit (CO2HCH2-CH2CO2H) doymuş, dibazik bir asit olup, renksiz kristaller verir. Erime noktası 186°C, kaynama noktası 235°C'dir. Buharları kolaylıkla su kaybedip, süksinik anhidride dönüşür.

Süksinik asit ve süksinik asidin alkali veya toprak alkali tuzları suda çözünür. Baryum süksinat sulu çözeltiden alkolle çöktürülür. Demir süksinat suda çözünmez ve bazan demiri diğer metallerden analitik olarak ayırmada kullanılır. Sodyum süksinat fosfor tri sülfürle ısıtıldığında tiyofen teşekkül eder. Süksinik asit, amonyum tartarat veya kalsiyum maltın bakteriyel fermantasyonundan üretilir. Sentetik olarak da etilen, C2H4, etilen diklorür, C2H4Cl2 ve etilen disiyanür, C2H4(CN)2 den elde edilebilir. Etilen disiyanür (Süksinonitril) hidrolizle direkt süksinik asit verir.

Soyu tükenmiş bir çam cinsinde bulunan ve Süksinik asit içeren fosil haline gelmiş reçinedir, taşlaşmış organik bir maddedir.

Kimyasal formülü C12H20O + Süksinik Asit + Su'dan oluşur.

Kehribarda % 3-8 nispetinde bulunan SÜKSİNİK ASİT organik bir bileşiktir. Kehribar reçinesinin özü, aktif maddesidir. Kimyasal adı bütandioik asittir. Diğer reçinelerde, fosilleşmiş ağaçlarda ve ekseri bitkilerde de bulunur. Gıda ve içeceklerde tatlandırıcı olarak kullanılır. Gıda katkı maddeleri kodu e363 tür. Ayrıca bakterilere karşı dayanıklılık özelliği vardır. Sigaranın içinde bulunan yüzlerce kimyasaldan da biridir. Canlıların enerji üretmesinde faydalandıkları krebs döngüsünde de yer alır. Düşük yoğunlukta birçok hayvanın dokularında yer alıp, ara metabolizma görevini ifa eder.

Süksinik Asit (bütandioik asit), bitki ve hayvan dokularında doğal olarak oluşan bir dikarboksilik asittir. Kimyasal ayrıca "Kehribar Ruhu" olarak da bilinir. Süksinik Asit ilk keşfedildiğinde, toz haline getirilerek ve bir kum banyosu kullanılarak damıtılarak kehribardan ekstrakte edildi. Esas olarak romatizmal ağrı ve ağrılarda harici olarak kullanılmıştır.

Karboksilik asitlerden neredeyse sonsuz esterler elde edilebilir. Esterler, bir asidin bir alkol ile birleştirilmesi ve bir su molekülünün çıkarılmasıyla üretilir. Karboksilik asit esterleri çeşitli doğrudan ve dolaylı uygulamalarda kullanılır.

Düşük zincirli esterler, lezzet verici baz malzemeleri, plastikleştiriciler, çözücü taşıyıcılar ve birleştirme maddeleri olarak kullanılır. Daha yüksek zincirli bileşikler, metal işleme sıvıları, yüzey aktif cisimleri, yağlayıcılar, deterjanlar, yağlama maddeleri, emülgatörler, ıslatıcılar, tekstil işlemleri ve yumuşatıcılarda bileşenler olarak kullanılır.

Esterler ayrıca çeşitli hedef bileşiklerin üretimi için ara ürünler olarak kullanılır. Neredeyse sonsuz esterler, uygun uygulama seçimleri için çok çeşitli viskozite, özgül ağırlık, buhar basıncı, kaynama noktası ve diğer fiziksel ve kimyasal özellikler sağlar.

SUCCINIC ACID (succinic acid)

Succinic acid (Succınıc acıd)'s production and use in the manufacture of lacquers, dyes, esters for perfumes, in photography, and in foods as a sequestrant, buffer and neutralizing agent may result in its release to the environment through various waste streams. Succinic acid (Succınıc acıd) is a constituent of almost all plant and animal tissues as it is a normal intermediary metabolite, being a component of the Kreb's Cycle. If released into the atmosphere, Succinic acid (Succınıc acıd) is expected to exist in both the particulate and vapor phases in the ambient atmosphere based on an extrapolated vapor pressure of 1.91X10-7 mm Hg at 25 °C. Vapor-phase Succinic acid (Succınıc acıd) will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals with an estimated half-life of about 6 days. Particulate-phase Succinic acid (Succınıc acıd) will be physically removed from the atmosphere by wet and dry deposition. If released to soil, an estimated Koc of 11 indicates that Succinic acid (Succınıc acıd) is expected to have very high mobility in soil. Volatilization from dry and wet soil surfaces is not expected to occur based on this compound's extrapolated vapor pressure and an estimated Henry's Law constant of 3.6X10-13 atm-cu m/mole at 25 °C, respectively. Biodegradation of Succinic acid (Succınıc acıd) in both soil and water is expected to be an important fate process based on a theoretical BOD of 78% measured using the MITI test. If released into water, Succinic acid (Succınıc acıd) is not expected to adsorb to suspended solids and sediments in the water column based on its estimated Koc. The potential for bioconcentration of Succinic acid (Succınıc acıd) in aquatic organisms is low based on an estimated BCF of 3. Volatilization from water surfaces is not expected to be important based on pKas of 4.16 and 5.6 (anions do not volatilize) and the estimated Henry's Law constant of the free acid.Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to Succinic acid (Succınıc acıd) may occur through inhalation and dermal contact with this compound at workplaces where Succinic acid (Succınıc acıd) is produced or used. Monitoring data indicate that the general population may be exposed to Succinic acid (Succınıc acıd) via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with consumer products containing Succinic acid (Succınıc acıd). (SRC)

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 11(SRC), determined from a log Kow of -0.59(2) and a regression-derived equation(3), indicates that Succinic acid (Succınıc acıd) is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.6X10-13 atm-cu m/mole(SRC), derived from its vapor pressure, 1.91X10-7 mm Hg(4), and water solubility, 8.32X1+4 mg/L(5). One of the pKa values of Succinic acid (Succınıc acıd) is 4.21(6), indicating that this compound will exist in the dissociated form in the environment and anions generally do not adsorb more strongly to suspended solids and sediment than their neutral counterparts(7), and will not volatilize. According to a classification scheme(8), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(9), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Succinic acid (Succınıc acıd), present at 100 mg/L, reached 78% of its theoretical BOD in 14 days using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(10), suggesting biodegradation may be an important environmental fate process in water.

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Succinic acid (Succınıc acıd), which has a vapor pressure of 1.91X10-7 mm Hg at 25 °C(2), is expected to exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase Succinic acid (Succınıc acıd) is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 6 days(SRC), calculated from its rate constant of 2.8X10-12 cu cm/molecule-sec at 25 °C that was derived using a structure estimation method(3). Particulate-phase Succinic acid (Succınıc acıd) may be removed from the air by wet and dry deposition(SRC).

URBAN/SUBURBAN: Succinic acid (Succınıc acıd) was detected in Los Angeles air samples, collected in June and Oct 1984, at concns ranging from 0.66 to 2.37 nmol/cu m in West Los Angeles and 1.84 to 2.13 nmol/cu m in downtown Los Angeles(1). Dust samples from downtown Los Angeles and a UCLA campus building contained Succinic acid (Succınıc acıd) at concns of 268 and 406 nmol/cu m, respectively(1). Succinic acid (Succınıc acıd) was detected in aerosol samples from urban Tokyo at an average concn of 37 ng/cu m between 1988-89(2). Succinic acid (Succınıc acıd) was detected in airborne aerosols from Schenectady, NY collected during Oct 1991 at concns ranging from 55 to 167 ng/cu m(3). Succinic acid (Succınıc acıd) was detected in atmospheric aerosols collected from Tsukuba, Japan(4). The average ambient annual concn of Succinic acid (Succınıc acıd) in fine particles collected from West Los Angeles, downtown Los Angeles, Pasadena, Rubidoux, and San Nicolas Island, CA in 1982 was 55.0, 66.5, 51.2, 84.1, and <0.02 ng/cu m, respectively(5). The average concn of Succinic acid (Succınıc acıd) in airborne aerosols collected from Takasaki and Karuizawa, Japan in July 1986 was 25.0 and 21.0 ng/cu m, respectively(6). The average daytime concn of Succinic acid (Succınıc acıd) in air samples collected from Takasaki and Karuizawa, Japan in July 1986 was 47.1 and 36.4 ng/cu m, respectively(7). The ambient concn of Succinic acid (Succınıc acıd) in West Los Angeles in Oct. 1982 was 14.1 ng/cu m(8). Aerosol samples collected from Tokyo in Feb and July 1992 contained Succinic acid (Succınıc acıd) at concns ranging from 139 to 279 ng/cu m(9).

Butanedioic acid (Succinic acid (Succınıc acıd)) is a known environmental transformation product of Sulcotrione.

Succinic acid (Succınıc acıd) is a known environmental transformation product of Linuron.

Succinic acid (Succınıc acıd) (/səkˈsɪnɪk/) is a dicarboxylic acid with the chemical formula (CH2)2(CO2H)2.[5] The name Succinic acid (Succınıc acıd) derives from Latin succinum, meaning amber. In living organisms, Succinic acid (Succınıc acıd) takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex 2 of the electron transport chain which is involved in making ATP, and as a signaling molecule reflecting the cellular metabolic state.[6] Succinic acid (Succınıc acıd) is marketed as food additive E363. Succinate is generated in mitochondria via the tricarboxylic acid cycle (TCA). Succinate can exit the mitochondrial matrix and function in the cytoplasm as well as the extracellular space, changing gene expression patterns, modulating epigenetic landscape or demonstrating hormone-like signaling.[6] As such, succinate links cellular metabolism, especially ATP formation, to the regulation of cellular function. Dysregulation of succinate synthesis, and therefore ATP synthesis, happens in some genetic mitochondrial diseases, such as Leigh syndrome, and Melas syndrome, and degradation can lead to pathological conditions, such as malignant transformation, inflammation and tissue injury.

Physical properties of Succinic acid (Succınıc acıd)

Succinic acid (Succınıc acıd) is a white, odorless solid with a highly acidic taste.[5] In an aqueous solution, Succinic acid (Succınıc acıd) readily ionizes to form its conjugate base, succinate (/ˈsʌksɪneɪt/). As a diprotic acid, Succinic acid (Succınıc acıd) undergoes two successive deprotonation reactions:

Commercial production of Succinic acid (Succınıc acıd)

Historically, Succinic acid (Succınıc acıd) was obtained from amber by distillation and has thus been known as spirit of amber. Common industrial routes include hydrogenation of maleic acid, oxidation of 1,4-butanediol, and carbonylation of ethylene glycol. Succinate is also produced from butane via maleic anhydride.[10] Global production is estimated at 16,000 to 30,000 tons a year, with an annual growth rate of 10%.[11]

Genetically engineered Escherichia coli and Saccharomyces cerevisiae are proposed for the commercial production via fermentation of glucose.

Chemical reactions of Succinic acid (Succınıc acıd)

Succinic acid (Succınıc acıd) (butanedioic acid) is a dicarboxylic acid that occurs naturally in plant and animal tissues. The chemical is also known as "Spirit of Amber." When Succinic acid (Succınıc acıd) was first discovered, it was extracted from amber by pulverizing and distilling it using a sand bath. It was primarily used externally for rheumatic aches and pains.

Almost infinite esters can be obtained from carboxylic acids. Esters are produced by combining an acid with an alcohol and removal of a water molecule. Carboxylic acid esters are used in a variety of direct and indirect applications.

Lower chain esters are used as flavoring base materials, plasticizers, solvent carriers and coupling agents. Higher chain compounds are used as components in metalworking fluids, surfactants, lubricants, detergents, oiling agents, emulsifiers, wetting agents, textile treatments and emollients.

Esters are also used as intermediates for the manufacture of a variety of target compounds. The almost infinite esters provide a wide range of viscosity, specific gravity, vapor pressure, boiling point, and other physical and chemical properties for the proper application selections.

Applications of Succinic acid (Succınıc acıd)

Acylation with Succinic acid (Succınıc acıd) is called succination. Oversuccination occurs when more than one succinate adds to a substrate.

Succinic acid (Succınıc acıd) is a dicarboxylic acid with the chemical formula (CH2)2(CO2H)2. The name derives from Latin succinum, meaning amber. In living organisms,Succinic acid (Succınıc acıd) takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by theenzyme succinate dehydrogenase in complex 2 of the electron transport chain which is involved in making ATP, and as a signaling molecule reflecting thecellular metabolic state. Succinate is generated in mitochondria via the tricarboxylic acid cycle (TCA), an energy-yielding process shared by all organisms.

Succinic acid (Succınıc acıd) is one of the natural acids found in foods such as broccoli, rhubarb, sugar beets, fresh meat extracts, various cheeses, and sauerkraut. All of these products have very distinct and marked flavours, which may be due in part to a flavour enhancement by the small amounts of Succinic acid (Succınıc acıd) naturally present. This would suggest that Succinic acid (Succınıc acıd) might have some interesting effects on various flavours that cannot be duplicated with other food acids.

For microbial production, several microorganisms can be used industrially, for example Actinobacillus succinogenes, Anaerobiospirillum succiniciproducens, and Mannheimia succiniciproducens (Chen and Patel, 2012) starting from corn starch, whey, cane molasses, glycerol, cereals, or lignocelluloses as biological raw materials. During fermentation, different byproducts such as acetate and formate could be formed, lowering the Succinic acid (Succınıc acıd) concentration. Furthermore, unfortunately, the production cost of the downstream production is still too high, representing 60%-70% of the total production cost for Succinic acid (Succınıc acıd). Improvements for low cost processes as well as for purification processes are under study in order to optimize Succinic acid (Succınıc acıd) production. Several global companies including BASF, Purac, BioAmber, Myriant, Amyris, and Mitsubishi Chemical Corporation are working on microbial production of Succinic acid (Succınıc acıd). 1,4-butanediol is nowadays produced from petrochemical resources by a chemical process. There is great interest in the microbial production of biobased 1,4-butanediol from sucrose as a renewable resource, or by catalytic aqueous-phase hydrogenation of biomass-based Succinic acid (Succınıc acıd), as reported by Chen and Patel (2012).

The Hofmann research group has termed the properties of compounds such as Succinic acid (Succınıc acıd) as umami taste modifiers. They found Succinic acid (Succınıc acıd), as well as L-theanine (a glutamic acid derivative), gallic acid and theogallin to enhance the umami taste in a green tea beverage at subthreshold concentrations (Kaneko et al. 2006). Whereas in isolation the Succinic acid (Succınıc acıd) has been denoted to have both sour and umami taste qualities, L-theanine was found to have astringent properties at 6 mmol/L but umami and sweet properties at 24 mmol/L; only gallic acid and theogallin had astringent properties in isolation. When prepared in model solutions with glutamic acid, these compounds all raised the umami intensity of MSG, depending on the level at which they were added (Kaneko et al. 2006).

Succinic acid (Succınıc acıd) has been used in large scale applications including the manufacture of lacquers, dyes, and esters for perfumes.1 In polymer research, Succinic acid (Succınıc acıd) has been utilized to prepare biocompatible hybrid dendritic-linear polyester-ethers.4

A study of the co-crystallization of cis-itraconazole with various 1,4-dicarboxylic acids, including Succinic acid (Succınıc acıd), has been reported.5 Succinic acid (Succınıc acıd) has been used as a matrix in infrared (IR) MALDI analytical methods.6,7,8 An analytical study of various low molecular weight organic acids, including Succinic acid (Succınıc acıd), using capillary zone electrophoresis-electrospray ionization mass spectrometry has been published.

Succinic acid (Succınıc acıd), systematically identified as butanedioic acid (pKa1 4.21, pKa2 5.72), is a value-added chemical building block, with an estimated 15,000 t/year world-wide demand predicted to expand to commodity chemical status with 270,000 t/year [7], [8] representing a potential >2 billion USD annual market. There are several elegant examples of bio-based production of succinate in Anaerobiospirillium succiniciproducens, Actinobacillus succinogenes, Succinivibrio dextrinosolvens, Corynebacterium glutanicum, Prevotella ruminocola, a recently isolated bacterium from bovine rumen, Mannheimia succiniciproducens, and a metabolically engineered Succinic acid (Succınıc acıd) over-producing E. coli [7], [8], [9], [10], [11], [12]. All of the hosts described are prokayotic that grow at neutral pH, and consequently secrete the salt, succinate, requiring a cost-intensive acidification and precipitation to reach the desired Succinic acid (Succınıc acıd). This concern is not specific to Succinic acid (Succınıc acıd) production, but rather universal when considering organic acid producing microbial cell factories [13]. S. cerevisiae represents a well-established, generally regarded as safe, robust, scalable (1L to 100,000L) industrial production host capable of growth on diverse carbon sources, chemically defined medium, both aerobic and anaerobic, and a wide pH operating range (3.0-6.0). We therefore addressed the question whether it is possible to metabolically engineer S. cerevisiae such that the carbon fluxes are redirected towards Succinic acid (Succınıc acıd), and hereby establish proof-of-concept of using this yeast as a general cell factory platform for chemical production.

Succinic acid (Succınıc acıd) (Butanedioic Acid) is a dicarboxylic acid of four carbon atoms. It occurs naturally in plant and animal tissues. It plays a significant role in intermediary metabolism (Krebs cycle) in the body. Krebs cycle (also called citric acid cycle; tricarboxylic acid cycle) is a sequence process of enzymatic reaction which a two-carbon acetyl unit is oxidized to carbon dioxide and water to provide energy in the form of high-energy phosphate bonds. Succinic acid (Succınıc acıd) is a colourless crystalline solid with a melting point of 185 -187 C; soluble in water; slightly dissolved in ethanol, ether, acetone and glycerine; not dissolved in benzene, carbon sulfide, carbon tetrachloride and oil ether. The common method of synthesis of Succinic acid (Succınıc acıd) is the catalytic hydrogenation of maleic acid or its anhydride. Carboxylic acid can yield acyl halides, anhydrides, esters, amides, and nitriles for the application of drug, agriculture, and food products, and other industrial uses.

Dicarboxylic acid is a compound containing two carboxylic acid, -COOH, groups. Straight chain examples are shown in table. The general formula is HOOC(CH2)nCOOH, where oxalic acid's n is 0, n=1 for malonic acid, n=2 for Succinic acid (Succınıc acıd), n=3 for glutaric acid, and etc. In substitutive nomenclature, their names are formed by adding -dioic' as a suffix to the name of the parent compound.

Bio-based Succinic acid (Succınıc acıd) used for medicine, spices, food preservatives, condiments, food additives, surface active agents, and widely used in the production of degradable plastics PBS, PBAT, PBSA, clothing biological fibers, polyurethane, polyether and other polyester products.

Acidic seasoning for Sake, Synthetic liquor, miso, soy sauce, soft drink, confectionery and so on.

Storage of Succinic acid (Succınıc acıd): Store in a cool, dry, well-ventilate area away from incompatible materials

Packing of Succinic acid (Succınıc acıd): 25 kgs net paper bag, 500 kgs net flexible container bag

L'acide succinique réagit facilement avec l'ammoniac NH3 pour donner des succinimides, avec le phénol pour engendrer des succinéides.

L'acide organique aux deux groupes carboxyles peut céder deux protons pour donner l'ion succinate, selon un équilibre acido-basique en solution aqueuse. C'est un acide faible : pKa1 = 4,2 et pKa2 = 5,6.

L'acide succinique était produit industriellement à partir de dérivés du pétrole (acétylène et formaldéhyde), mais en 2008, un premier pilote industriel (installé en 2007 dans la bio-raffinerie de Pomacle-Bazancourt près de Reims, disposant d'une capacité de production de 2000t/an) a pu en produire à partir de sucres et résidus lignocellulosiques fermentés par E. Coli en atmosphère enrichie en CO25.

L'acide succinique est une molécule biologique. © Ben Mills, Wikimedia, domaine public

L'acide succinique est un acide présent dans tous les organismes vivants, premièrement identifié dans le succin (aussi appelé ambre jaune), d'où son nom.

acide succinique \a.sid syk.si.nik\ masculin invariable

Améliorez l'empreinte environnementale de vos produits avec l'acide bio-succinique à la pointe du progrès.

En plus d'être une solution de remplacement pour l'acide succinique à base de pétrole, il peut également remplacer l'acide adipique à base de pétrole. Comparé aux di-acides traditionnels, l'empreinte environnementale de BIOSUCCINIUM® est bien meilleure, ce qui permet aux produits chimiques de la chaîne de valeur de répondre à vos exigences en matière de développement durable.

L'acide succinique biosourcé en compétition avec les dérivés pétroliers

Le rapport sur l'acide succinique montre un décalage entre les estimations de l'offre et de la demande. En effet, il existe une réelle compétitivité entre l'acide succinique biosourcé et d'origine fossile : les estimations d'évolution du marché du pétrole ont entraîné un fort attrait pour l'acide succinique biosourcé, même si le prix du baril reste inférieur aux prédictions. De plus, la demande en 1,4-butanediol, considéré comme un marché pour l'acide succinique d'origine biologique, n'a pas suivi les attentes du marché, et aucune unité de production ne devrait devenir commerciale avant 2023. Jusqu'à cette date au moins, le marché de l'acide succinique devrait se limiter aux applications de spécialités, telles que le polymère de polybutylène succinate (PBS) biosourcé et les revêtements. L'évolution du marché de l'acide succinique sera fortement dépendante de l'évolution du prix du pétrole.

L'acide succinique (Succinic Acid) (acide butanedioïque) est un acide dicarboxylique qui se produit naturellement dans les tissus végétaux et animaux. Le produit chimique est également connu sous le nom de «Spirit of Amber». Lorsque L'acide succinique (Succinic Acid) a été découvert pour la première fois, il a été extrait de l'ambre en le pulvérisant et en le distillant à l'aide d'un bain de sable. Il était principalement utilisé à l'extérieur pour les douleurs et les douleurs rhumatismales.

Des esters presque infinis peuvent être obtenus à partir d'acides carboxyliques. Les esters sont produits en combinant un acide avec un alcool et en éliminant une molécule d'eau. Les esters d'acide carboxylique sont utilisés dans une variété d'applications directes et indirectes.

Les esters à chaîne inférieure sont utilisés comme matières de base aromatisantes, plastifiants, supports de solvants et agents de couplage. Les composés à chaîne supérieure sont utilisés comme composants dans les fluides de travail des métaux, les tensioactifs, les lubrifiants, les détergents, les agents huilants, les émulsifiants, les agents mouillants, les traitements textiles et les émollients.

Les esters sont également utilisés comme intermédiaires pour la fabrication d'une variété de composés cibles. Les esters presque infinis offrent une large gamme de viscosité, de gravité spécifique, de pression de vapeur, de point d'ébullition et d'autres propriétés physiques et chimiques pour les sélections d'application appropriées.