MONTANOX 20
Montanox 20, a nonionic surfactant with 20 ethylene oxide units, is widely utilized in creating stable oil-in-water emulsions for products like lotions, shampoos, and body mist.
In the field of biochemistry, Montanox 20 is essential as a washing and blocking agent in immunoassays and can also be used for cell lysis and protein extraction.
Montanox 20 is valued for its versatility, serving as a wetting agent in the elastomer industry, a stabilizer in food products, and a non-toxic remover for philatelic applications.
CAS Number: 9005-64-5
EC Number: 500-018-3
Molecular Formula: C26H50O10
Molecular weight: 522.7
Synonyms: Tween 20, 9005-64-5, POLYOXYETHYLENE SORBITAN MONOLAURATE, Polyoxyethylene (20) sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate, Polysorbate (INN), 9005-66-7, Sorbimacrogol laurate 300, 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate, 2-(2-(3,4-Bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)ethoxy)ethyl dodecanoate, 2-[2-[3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate, Alkest TW 20, Polyoxyethylene Sorbitan Monolaurate Kosher, FT-0645136, Polyoxyethylene Sorbitan Monolaurate 20 NF, D05565, D05566, D05567, 3,6-Anhydro-1-O-[2-(dodecanoyloxy)ethyl]-2,4,5-tris-O-(2-hydroxyethyl)hexitol, Polysorbate 20 (NF), Polysorbate 40 (NF), Polysorbate 60 (NF), Tween(R) 20, Tween (R) 20, Tween 20 (TN), Tween 40 (TN), Tween 60 (TN), SCHEMBL118527, POE (6) sorbitol monolaurate, POE(20) sorbitan monolaurate, CHEMBL371631, Ethoxylated Sorbitan monolaurate, POE (20) sorbitan monolaurate, DTXSID60922815, MFCD00165986, E432, Polysorbate 20 (NF), Polysorbate 40 (NF), Polysorbate 60 (NF), Tween(R) 20, Tween (R) 20, Tween 20 (TN), Tween 40 (TN), Tween 60 (TN), SCHEMBL118527, POE (6) sorbitol monolaurate, POE(20) sorbitan monolaurate, CHEMBL371631, Ethoxylated Sorbitan monolaurate, POE (20) sorbitan monolaurate, DTXSID60922815, MFCD00165986, E432, Polyoxyethylene Sorbitan Monolaurate Kosher, FT-0645136, Polyoxyethylene Sorbitan Monolaurate 20 NF, D05565, D05566, D05567, 3,6-Anhydro-1-O-[2-(dodecanoyloxy)ethyl]-2,4,5-tris-O-(2-hydroxyethyl)hexitol
Montanox 20 is commonly used as an emulsifier and solubilizer in various applications, including pharmaceuticals, food, and cosmetics.
Montanox 20 is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid.
Montanox 20's stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.
As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.
Montanox 20 is used as a wetting agent in flavored mouth drops, helping to provide a spreading feeling to other ingredients like SD alcohol and mint flavor.
Montanox 20 is also used as wetting agent in rubber balers in the elastomer industry.
Montanox 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies
Montanox 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family.
Montanox 20 is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid.
Montanox 20 is a nonionic detergent widely used in biochemical applications.
Montanox 20 has been used as an emulsifying agent for the preparation of stable oil-in-water emulsions.
Montanox 20 has been used in pre-extraction of membranes to remove peripheral proteins (used at 2% for extraction of membrane-bound proteins).
Montanox 20 has been used as a blocking agent for membrane based immunoassays at a typical concentration of 0.05%.
Montanox 20 can be used for lysing mammalian cells at a concentration of 0.005 to 0.5%.
Montanox 20 lubricates the skin and has a soothing effect.
Montanox 20 is used in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.).
Montanox 20 is widely used for body mist and linen sprays.
Montanox 20 has been used as a blocking agent for membrane based immunoassays at a typical concentration of 0.05%.
Montanox 20 is suitable for use as a solubilizing agent of membrane proteins and as a blocking agent in Western blotting.
Montanox 20 can be used for lysing mammalian cells at a concentration of 0.05 to 0.5%.
Montanox 20 is found as an ingredient in most body care products, cosmetics, and wet wipes.
Montanox 20 is often used in combination with other emulsifiers such as mono- and diglycerides or sorbitan monostearates for a variety of purposes, such as dispersing flavors and colors, solubilizing essential oils and vitamins, and improving volume and texture in baked goods.
Montanox 20 is a highly hydrophilic surfactant
Montanox 20 is approved as food additives.
Montanox 20 is a useful emulsifier, dispersant and solvent for aroma chemicals and oils.
Montanox 20 is a nonionic solubilizing agent used in the textile industry.
Montanox 20 is a polysorbate type nonionic surfactant formed by ethoxylation of sorbitan prior to the addition of lauric acid.
Montanox 20 is used as a detergent and emulsifier in pharmacological practice.
Montanox 20 is a nonionic surfactant.
Montanox 20 is used as an emulsifier and a dispersing agent that allows oil and water to mix without the use of alcohol.
Montanox 20 is a water-soluble yellowish liquid.
Montanox 20 is an odor remover and stabilizer.
Montanox 20 lubricates the skin and has a soothing effect.
Montanox 20 is used in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.).
In addition, Montanox 20 is widely used for body mist and linen sprays.
Montanox 20 is found as an ingredient in most body care products, cosmetics, and wet wipes.
Montanox 20 is a nonionic surfactant
Montanox 20 is used as an emulsifier and a dispersing agent that allows oil and water to mix without the use of alcohol.
Montanox 20 is a water-soluble yellowish liquid.
Montanox 20 is an odor remover and stabilizer.
Montanox 20 is derived from coconut oil.
Montanox 20 is non-toxic.
Montanox 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.
Montanox 20 is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid.
Montanox 20's stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.
Montanox 20 is often used in combination with other emulsifiers such as mono- and diglycerides or sorbitan monostearates for a variety of purposes, such as dispersing flavors and colors, solubilizing essential oils and vitamins, and improving volume and texture in baked goods.
Montanox 20 is a highly hydrophilic surfactant
Montanox 20 is approved as food additives.
Montanox 20 is a useful emulsifier, dispersant and solvent for aroma chemicals and oils.
Montanox 20 is a nonionic solubilizing agent used in the textile industry.
Montanox 20 is a polysorbate type nonionic surfactant formed by ethoxylation of sorbitan prior to the addition of lauric acid.
Montanox 20 is used as a detergent and emulsifier in pharmacological practice.
Applications of Montanox 20:
Biotechnical Applications:
In biological techniques and sciences, Montanox 20 has a broad range of applications.
For example, Montanox 20 is used as a washing agent in immunoassays.
Montanox 20 helps to prevent non-specific antibody binding.
In this major application, Montanox 20 is dissolved in Tris-buffered saline or phosphate buffered saline at dilutions of 0.05% to 0.5% v/v.
These buffers are used for washes beTween each immunoreaction, to remove unbound immunologicals, and eventually for incubating solutions of immunoreagents (labeled antibodies) to reduce nonspecific background.
Montanox 20 is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.
Industrial and Domestic Applications:
Montanox 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.
Montanox 20 is also used as wetting agent in rubber balers in the elastomer industry.
Montanox 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies
Montanox 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family.
Montanox 20 is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid.
Montanox 20 is responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment.
Montanox 20 is a nonionic detergent widely used in biochemical applications.
Montanox 20 has been used as an emulsifying agent for the preparation of stable oil-in-water emulsions.
Montanox 20 has been used in pre-extraction of membranes to remove peripheral proteins (used at 2% for extraction of membrane-bound proteins).
Montanox 20 has been used as a blocking agent for membrane based immunoassays at a typical concentration of 0.05%.
Montanox 20 can be used for lysing mammalian cells at a concentration of 0.005 to 0.5%.
Montanox 20 has been used as a component of:
Washing buffer and blocking buffer in Western blotting
Blocking buffer in immunohistochemistry
Washing buffer in ELISA (enzyme linked immunosorbent assay)
Reaction mixture in PCR (polymerase chain reaction)
Other Applications:
Detergent production
Emulsifiers
Mouth droppers
Biotechnological Techniques
Immunoassays
Biochemistry laboratories
Suspension stabilizers
Pharmacological Applications
Elastomer Industry
Peripheral Protein Synthesis
Immunological Tests
Surfactants
Deodorizing Products
Shampoo production
Liquid soap manufacture
Body lotions
Wet Wipes production
Cosmetics industry
Skin care products
Textile industry
Preparation Instructions of Montanox 20:
Montanox 20 is miscible in water (100 mg/ml), yielding a clear, yellow solution.
Montanox 20 is also miscible with alcohol, dioxane, and ethyl acetate; and is practically insoluble in liquid paraffin and fixed oils.
Storage/Stability of Montanox 20:
Aqueous solutions of polysorbates undergo autoxidation during storage, with changes being catalyzed by light, increased temperature, and copper sulfate.
Autoclaving is not recommended without testing for changes in properties.
Montanox 20 may not be stable to autoclaving, particularly with metal cations in buffer solutions.
Montanox 20 is heat sensitive and will darken when exposed to elevated temperatures.
Tweens have been reported to be incompatible with alkalis, heavy metal salts, phenols, and tannic acid.
Tweens may reduce the activity of many preservatives.
Handling and Storage of Montanox 20:
Storage:
Store in a cool, dry place away from direct sunlight and incompatible materials like strong acids or oxidizing agents.
Handling:
Use standard personal protective equipment (PPE) like gloves and safety glasses when handling large quantities or in an industrial setting.
Avoid inhaling aerosols or mist.
Stability and Reactivity of Montanox 20:
Chemical Stability:
Montanox 20 is stable under normal conditions of use and storage.
Conditions to Avoid:
Avoid exposure to extreme heat, open flames, and incompatible materials.
Incompatible Materials:
Strong oxidizing agents, strong acids, and strong bases may cause a reaction with Montanox 20.
Hazardous Decomposition Products:
Under fire conditions, Montanox 20 may decompose to produce toxic fumes, including carbon monoxide (CO) and carbon dioxide (CO2).
Hazardous Polymerization:
Hazardous polymerization will not occur.
First Aid Measures of Montanox 20:
Ingestion:
If swallowed, rinse mouth with water.
Do not induce vomiting unless directed by medical personnel.
Seek medical advice if large quantities have been ingested.
Skin Contact:
Wash affected area with plenty of soap and water.
If skin irritation or rash occurs, get medical attention.
Eye Contact:
Rinse eyes immediately with plenty of water for at least 15 minutes, lifting the upper and lower eyelids.
Remove contact lenses if present and easy to do.
Seek medical attention if irritation persists.
Inhalation:
Move the affected person to fresh air.
If they experience any symptoms such as coughing or difficulty breathing, seek medical attention immediately.
Fire-Fighting Measures of Montanox 20:
Suitable Extinguishing Media:
Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide (CO2) to extinguish fires involving Montanox 20.
Unsuitable Extinguishing Media:
Avoid using a solid water stream as Montanox 20 may scatter and spread the fire.
Specific Hazards:
Montanox 20 may produce toxic fumes under fire conditions, including carbon monoxide (CO) and carbon dioxide (CO2).
Protective Equipment:
Firefighters should wear self-contained breathing apparatus (SCBA) and full protective gear to prevent exposure to toxic fumes.
Special Precautions:
Cool containers exposed to fire with water spray to prevent overheating and bursting.
Accidental Release Measures of Montanox 20:
Personal Precautions:
Wear appropriate personal protective equipment (PPE), including gloves, eye protection, and, if necessary, a respirator. Ensure adequate ventilation.
Environmental Precautions:
Prevent entry into waterways, drains, or sewers.
Contain the spill if safe to do so.
Containment Methods:
Contain and collect spillage with non-combustible absorbent material (e.g., sand, earth, diatomaceous earth) and place Montanox 20 in a container for disposal according to local regulations.
Cleaning Methods:
Clean the spill area thoroughly with water and detergent to remove residue.
Dispose of contaminated materials in accordance with local regulations.
Exposure Controls and Personal Protection of Montanox 20:
Exposure Limits:
No specific occupational exposure limits have been established for Montanox 20.
However, exposure controls should still be in place.
Engineering Controls:
Ensure adequate ventilation, particularly in areas where aerosols or vapors may be generated.
Use local exhaust ventilation or other engineering controls to minimize exposure.
Personal Protective Equipment (PPE):
Eye Protection:
Wear safety goggles or face shield if splashing is possible.
Skin Protection:
Wear protective gloves and clothing to prevent skin contact.
Nitrile or rubber gloves are recommended.
Respiratory Protection:
If exposure to aerosols or vapors is possible, wear an appropriate respirator (e.g., NIOSH-approved respirator with organic vapor/acid gas cartridge).
Hygiene Measures:
Wash hands thoroughly after handling and before eating, drinking, or smoking.
Remove contaminated clothing and wash before reuse.
Identifiers of Montanox 20:
CAS Number: 9005-64-5
EC Number: 500-018-3
Molecular Formula: C26h50o10
Molecular Weight: 522.7
IUPAC Name: 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl Dodecanoate
CAS Number: 9005-64-5
EC Number: 500-018-3
UNII (FDA Unique Ingredient Identifier): 7T1F30V5YH
PubChem CID: 5281955
RTECS Number: TR7400000
IUPAC Name: Polyoxyethylene (20) sorbitan monolaurate
Properties of Montanox 20:
Molecular Weight: 522.7
XLogP3-AA: 2.5
Exact Mass: 522.34039779
Monoisotopic Mass: 522.34039779
Topological Polar Surface Area: 133 Ų
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 26
Heavy Atom Count: 36
Formal Charge: 0
Complexity: 507
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 4
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical Description: It is a lemon to amber-coloured oily liquid
Color: Lemon- to amber-colored
Form: liquid
Odor: Characteristic odor
Taste: Bitter
Melting Point: 110 °C
Solubility: Soluble in water, ethanol, methanol, ethyl acetate and dioxane. Insoluble in mineral oil and petroleum ether
Density: 1.095 g/mL
