2-BROMOPROPANE
2-Bromopropane is a clear, colorless, volatile liquid and organobromine compound with the molecular formula C₃H₇Br, primarily used as an alkylating agent in organic synthesis to introduce isopropyl groups into molecules.
2-Bromopropane is widely utilized in the manufacture of pharmaceuticals, agrochemicals, and specialty chemicals, and serves as a versatile reagent in the synthesis of ethers, amines, Grignard reagents, and other organic derivatives.
Despite its utility, 2-Bromopropane poses significant health and environmental risks due to its flammability, toxicity, and potential to cause central nervous system depression, requiring strict handling and safety precautions.
CAS Number: 75-26-3
EC Number: 200-855-1
Molecular Weight: 122.99
Chemical formula: C3H7Br
Synonyms: 2-Bromopropane, 75-26-3, ISOPROPYL BROMIDE, Propane, 2-bromo-, Isopropylbromide, 2-BROMO-PROPANE, 2-bromo propane, UNII-R651XOV97Z, R651XOV97Z, MFCD00000147, sec-Propyl bromide, CCRIS 7919, HSDB 623, EINECS 200-855-1, UN2344, i-propylbromide, AI3-18127, 2-brompropan, iso-propylbromide, i-propyl bromide, 2-bromanylpropane, 2-propyl bromide, 1-isopropylbromide, iso-propyl bromide, i-PrBr, iso-C3H7Br, 1-bromo-1-methylethane, 2-Bromopropane, 99%, EC 200-855-1, 2-Bromopropane, 2-Bromopropane, >=99%, DSSTox_CID_10197, DSSTox_RID_78840, DSSTox_GSID_30197, SCHEMBL10251, CHEMBL451810, DTXSID7030197, 2-Bromopropane, analytical standard, AMY37129, ZINC2041293, Tox21_200356, BBL027287, BR1118, STL146524, AKOS000119846, MCULE-4068304617, CAS-75-26-3, NCGC00091451-01, NCGC00091451-02, NCGC00257910-01, VS-08520, 2-Bromopropane, purum, >=99.0% (GC), B0639, FT-0611602, D87619, A838364, Q209323, J-508539, F0001-1897, 200-855-1, 2-Bromopropane, 2-Bromopropane, 2-Bromo-propane, 2-Brompropan, 75-26-3, Isopropyl Bromide, Propane, 2-bromo-, 1219799-22-0, 18668-72-9, 2-bromopropane radical cation, 2-Bromopropane|Isopropyl bromide, 2-Bromopropane-1,1,1,2-d4, 2-Bromopropane-1,1,1,3,3,3-d6, 2-Bromopropane-1,1,1-d3, 2-Bromopropane-2-d1, 2-BroMopropane--d4, 2-bromopropane-d6, 2-Bromopropane-d7, 39091-63-9, 3-Bromo-1-butyne, 4067-80-5, 52809-76-4, 688361-45-7, iso-C3H7Br, iso-Propyl bromide, Isopropyl bromide, Isopropylbromide, sec-Propyl bromide, VS-08520
2-Bromopropane is a clear, colorless, and volatile liquid with a sweet, ether-like odor.
2-Bromopropane is an organobromine compound with the chemical formula C₃H₇Br, and it belongs to the class of alkyl halides.
2-Bromopropane is primarily used as an alkylating agent in organic synthesis, where it introduces the isopropyl group into various molecules through nucleophilic substitution reactions.
2-Bromopropane is a valuable intermediate in the manufacture of pharmaceuticals, agrochemicals, and specialty chemicals.
Due to its high reactivity and relatively simple structure, 2-Bromopropane is often used in laboratory settings for the synthesis of ethers, amines, and other derivatives.
2-Bromopropane has limited solubility in water but is miscible with most organic solvents such as alcohols, ethers, and chloroform.
Although useful, 2-Bromopropane must be handled with caution, as it is flammable, toxic, and can cause irritation to the skin, eyes, and respiratory tract.
Prolonged exposure or improper handling may lead to serious health risks, including central nervous system depression.
As such, appropriate personal protective equipment and ventilation are necessary when using 2-Bromopropane in industrial or laboratory environments.
2-Bromopropane is the halogenated hydrocarbon with the formula CH3CHBrCH3.
2-Bromopropane is a colorless liquid.
2-Bromopropane is used for introducing the isopropyl functional group in organic synthesis.
2-Bromopropane is prepared by heating isopropanol with hydrobromic acid.
2-Bromopropane is also known as 75-26-3, 2-bromo-propane, 2-Bromopropane, Propan-2-bromo with Molecular Formula of C3H7Br and Molecular Weight of 122.99168.
2-Bromopropane is manufactured by heating isopropyl alcohol with HBr and is available in colorless liquid form.
Some of 2-Bromopropane properties include Boiling Point of 59-60°C, Melting Point of -89.0°C, Density/Specific Gravity of 1.31 at 20°C/4°C with miscible solubility with chloroform, ether, alcohol, benzene; slight solubility in acetone and in water (3,180 mg/L at 20°C).
Further, 2-Bromopropane has Surface Tension of 3.5348X10-2 N/m at melting point, Vapor Density of 4.27 (Air=1) and Vapor Pressure of 216 mm Hg at 25°C.
2-Bromopropane is the halogenated hydrocarbon with the formula CH3CHBrCH3.
2-Bromopropane is a colorless liquid.
2-Bromopropane is used for introducing the isopropyl functional group in organic synthesis.
2-Bromopropane is prepared by heating isopropanol with hydrobromic acid.
2-Bromopropane is used for introducing the isopropyl functional group in organic synthesis.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
2-Bromopropane has proved to be a useful reagent for amino acids dissolved in dimethylsulfoxide/sodium hydride, except for the determination of arginine.
Methylation of acids with diazomethane has also been used for metabolic profiling despite the formation of artefacts.
Resin-mediated methylation of polyfunctional acids found in fruit juices has also proved successful.
Fumaric, succinic, malic, tartaric, isocitric and citric acids, isolated from fruit juices by trapping onto anionic ion exchange resins, can be efficiently converted to methyl esters by reaction with methyl iodide in both supercritical carbon dioxide and acetonitrile.
To provide for the analysis of even short chain fatty acids in serum, a procedure has been developed with benzyl bromide.
This has been successfully employed for serum and urine organic acid profiling.
The method cannot be used for citric acid or sugar-related acids.
Exposure to 2-Bromopropane has been associated with adverse reproductive effects in men and women.
There are also some reports suggesting that maternal formaldehyde exposure is related to delayed conception and miscarriage, and exposure to trinitrotoluene or trichloroethylene may be harmful for the reproductive health of men.
Formamide, dimethylformamide and n-methyl-2-pyrrolidone have also been shown to cause fetotoxic and teratogenic effects in laboratory animals, but there are no data on their effects in humans.
In summary, the epidemiologic evidence suggests that high maternal exposure to solvents may represent a hazard for the developing fetus and may impair female fertility.
The results for male fertility are less conclusive.
The findings on individual solvents must also be interpreted with caution, because coincident exposure to several agents makes 2-Bromopropane difficult to ascribe adverse effects to a specific compound.
Nevertheless, the study results are supportive of adverse effects of some glycol ethers, tetrachloroethylene, toluene, benzene and carbon disulfide on reproduction.
2-Bromopropane would be prudent to minimize exposure to organic solvents.
2-Bromopropane is an organobromine compound with the molecular formula C₃H₇Br and a molecular weight of approximately 122.99 g/mol.
2-Bromopropane appears as a colorless, flammable, volatile liquid with a sweet, ether-like odor and is commonly categorized as an alkyl halide due to the presence of a bromine atom bonded to a secondary carbon.
2-Bromopropane is primarily used as an alkylating agent in organic synthesis, where it reacts with nucleophiles to introduce the isopropyl group into various molecules, facilitating the production of intermediates for pharmaceuticals, agrochemicals, dyes, and surfactants.
2-Bromopropane's high electrophilicity makes it especially useful in SN2 substitution reactions, particularly in laboratory-scale synthesis of ethers, amines, and other substituted organics.
2-Bromopropane is sparingly soluble in water, but it mixes well with organic solvents such as alcohols, ethers, chloroform, and acetone.
2-Bromopropane is commonly used in Grignard reagent preparations, where it serves as a precursor to organomagnesium compounds that are essential for forming carbon–carbon bonds in complex molecular frameworks.
In addition to its role in synthesis, 2-Bromopropane is also used in polymer chemistry and the production of flame retardants and plasticizers.
Despite its utility, 2-Bromopropane poses notable health and safety hazards.
2-Bromopropane is toxic by inhalation, ingestion, or skin contact, and exposure may result in irritation of the eyes, skin, and respiratory tract, along with symptoms such as headache, dizziness, or drowsiness.
Prolonged or high-level exposure can depress the central nervous system and may potentially cause liver or kidney damage.
2-Bromopropane is also considered an environmental hazard, as its volatility and potential to form free radicals can contribute to air pollution and ozone layer depletion when released in large quantities.
Moreover, under certain conditions, 2-Bromopropane can form explosive mixtures with air, particularly at elevated temperatures or in confined, poorly ventilated spaces.
Because of these risks, it is essential to handle 2-Bromopropane using appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats, and to conduct all operations within a well-ventilated fume hood.
Storage should be in tightly sealed containers, away from heat sources, oxidizing agents, and direct sunlight.
Despite its hazardous nature, when used responsibly and with proper precautions, 2-Bromopropane remains a versatile and valuable reagent in modern synthetic organic chemistry.
Market Overview of 2-Bromopropane:
The global market for 2-Bromopropane is niche but essential, primarily driven by its demand in pharmaceuticals, agrochemicals, and specialty chemical synthesis.
As a key alkylating agent and intermediate, 2-Bromopropane holds significant value in fine chemical industries where high-purity reagents are required.
Growth in the pharmaceutical sector, especially in emerging economies, has positively influenced the market due to increased production of active pharmaceutical ingredients (APIs) requiring isopropylated precursors.
In addition, agrochemical manufacturers are utilizing 2-Bromopropane for synthesizing next-generation pesticides and herbicides with greater efficiency and lower environmental persistence.
The market is geographically dominated by North America, Europe, and parts of Asia-Pacific, particularly India and China, where 2-Bromopropane is manufactured and consumed for local and export needs.
However, 2-Bromopropane's usage is regulated in many countries due to concerns over toxicity, flammability, and potential environmental hazards, which may limit market expansion in stricter regulatory environments.
Additionally, rising environmental awareness and demand for green chemistry alternatives are prompting some producers to explore biobased or less hazardous substitutes.
Nevertheless, 2-Bromopropane continues to see steady demand in research and industrial synthesis, and market participants focus on ensuring safe handling, cost-effective production, and compliance with global safety standards.
The future of the 2-Bromopropane market will likely depend on regulatory developments, technological advancements, and the evolving needs of custom synthesis sectors.
Synthesis of pharmaceuticals, dyes, other organics.
2-Bromopropane is a general reagent used to introduce isopropyl group as in the case of the synthesis of various Buchwald ligands.
2-Bromopropane can also be used as a starting material in the total synthesis of lamellarin D, lamellarin H, ningalin B and (±)-dichroanal.
2-Bromopropane serves as an alkylating agent in organic synthesis.
2-Bromopropane is also used as an intermediate to form alkylated amines and alkylated metallic compounds.
Further, 2-Bromopropane acts as a solvent for industrial cleaning, degreasing, metal processing and finishing, electronics, aerospace and aviation, aerosols, textiles, adhesives and inks.
In addition, 2-Bromopropane is used for introducing the isopropyl functional group in organic synthesis.
2-Bromopropane is used as a freon substitute.
2-Bromopropane is used in organic synthesis.
2-Bromopropane is used in the synthesis of pharmaceuticals, dyes and other organics.
2-Bromopropane is primarily used as an alkylating agent in organic synthesis, where it facilitates the introduction of isopropyl groups into a wide range of organic molecules through nucleophilic substitution reactions.
This makes 2-Bromopropane a valuable reagent in the preparation of ethers, esters, amines, and various other derivatives in both academic and industrial laboratories.
2-Bromopropane plays an important role in the pharmaceutical industry as an intermediate in the synthesis of active drug compounds, particularly those requiring branched alkyl chains for biological activity.
In agrochemical production, 2-Bromopropane is used to develop pesticides and herbicides, contributing to improved bioefficacy and environmental persistence.
Additionally, 2-Bromopropane is utilized in the formation of Grignard reagents, such as isopropyl magnesium bromide, which are essential for constructing carbon–carbon bonds in advanced organic syntheses.
2-Bromopropane also finds application in the polymer and plastics industries, where it is used in the synthesis of specialized additives, plasticizers, and brominated flame retardants.
2-Bromopropane's versatility, reactivity, and functional utility make it an indispensable compound in modern chemical manufacturing, despite the need for careful handling due to its toxicity and volatility.
Here are the uses of 2-Bromopropane in detail:
Alkylating Agent in Organic Synthesis:
2-Bromopropane is widely used as a reagent for introducing an isopropyl group into molecules through nucleophilic substitution (SN2) reactions.
2-Bromopropane is valuable in the synthesis of ethers, esters, amines, and other organic compounds.
Pharmaceutical Intermediate:
2-Bromopropane is a key intermediate in the manufacture of pharmaceutical compounds, especially those that require branched alkyl groups.
2-Bromopropane contributes to the structural diversity of active pharmaceutical ingredients (APIs).
Agrochemical Synthesis:
2-Bromopropane is used in the synthesis of pesticides, herbicides, and fungicides, helping to develop molecules with improved bioavailability and environmental stability.
Grignard Reagent Formation:
2-Bromopropane is employed in the formation of Grignard reagents (such as isopropyl magnesium bromide), which are essential intermediates for constructing carbon–carbon bonds in complex organic synthesis.
Polymer Industry:
2-Bromopropane is sometimes used in polymer modification or in the synthesis of specialty monomers and additives, contributing to plasticizers and stabilizers for industrial polymers.
Research and Development:
In academic and industrial research laboratories, 2-Bromopropane is used for studying reaction mechanisms, testing reactivity, and preparing custom-designed molecules for medicinal or materials chemistry.
Flame Retardants and Plastic Additives:
2-Bromopropane serves as a chemical building block in the production of brominated flame retardants, which are added to plastics, textiles, and electronics to reduce flammability.
Industry Uses:
Intermediates
Production of 2-Bromopropane:
2-Bromopropane is commercially available.
2-Bromopropane may be prepared in the ordinary manner of alkyl bromides, by reacting isopropanol with phosphorus and bromine, or with phosphorus tribromide.
2-Bromopropane is primarily produced through the reaction of isopropyl alcohol with hydrobromic acid (HBr).
This is a classic substitution reaction, where the hydroxyl group (–OH) of isopropyl alcohol is replaced by a bromine atom to yield 2-Bromopropane and water.
The process can be represented by the following chemical equation:
(CH₃)₂CHOH + HBr → (CH₃)₂CHBr + H₂O
This reaction typically occurs under acidic conditions and elevated temperatures to enhance conversion efficiency.
In some industrial processes, sulfuric acid may be used as a catalyst to promote the protonation of the alcohol, making it a better leaving group for the bromide ion to attack.
Alternatively, 2-Bromopropane can also be synthesized via the reaction of isopropyl alcohol with phosphorus tribromide (PBr₃) or phosphorus and bromine, especially when higher purity is desired.
These methods are more common in laboratory-scale or specialty chemical production due to better selectivity and fewer side products.
Care must be taken during production due to the volatile, flammable, and toxic nature of both the reactants and 2-Bromopropane.
The final product is usually purified by distillation, and quality control is essential to ensure that it meets the required purity specifications for industrial or pharmaceutical use.
Additionally, manufacturers implement strict safety protocols and environmental controls to manage emissions and waste due to the hazardous properties of brominated compounds.
General Manufacturing Information:
Industry Processing Sectors:
All other basic inorganic chemical manufacturing.
Pharmacology and Biochemistry of 2-Bromopropane:
MeSH Pharmacological Classification:
Solvents:
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar.
Mutagens:
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids.
A clastogen is a specific mutagen that causes breaks in chromosomes.
Identification of 2-Bromopropane:
Analytic Laboratory Methods:
Method: NIOSH 1025
Procedure: Gas chromatography with flame ionization detector
Analyte: 2-Bromopropane
Matrix: air
Detection Limit: 1.0 ug/sample.
Method: OSHA PV2062
Procedure: Gas chromatography using flame ionization detector
Analyte: 2-Bromopropane
Matrix: air
Detection Limit: 0.004 ppm (0.020 mg/ cu m).
Purification Methods of 2-Bromopropane:
Wash the bromide with 95% H2SO4 (concentrated acid partially oxidised 2-Bromopropane) until a fresh portion of acid did not become coloured after several hours, then with water, aqueous NaHSO3, aqueous 10% Na2CO3 and again with water.
The H2SO4 can be replaced by conc HCl.
Prior to this treatment, 2-Bromopropane has been purified by bubbling a stream of oxygen containing 5% ozone through 2-Bromopropane for 1hour, followed by shaking with 3% hydrogen peroxide solution, neutralising with aqueous Na2CO3, washing with distilled water and drying.
Alternatively, 2-Bromopropane has been treated with elemental bromine and stored for 4 weeks, then extracted with aqueous NaHSO3 and dried with MgSO4.
After the acid treatment, 2-Bromopropane can be dried with Na2SO4, MgSO4 or CaH2, and fractionally distilled.
Synthesis of 2-Bromopropane:
2-Bromopropane is synthesized through nucleophilic substitution reactions involving isopropyl alcohol ((CH3)2CHOH) and a brominating agent.
The most common and industrially practical method is via reaction with hydrobromic acid (HBr):
HBr Method (Acid-Catalyzed Substitution):
This method involves heating isopropyl alcohol with concentrated hydrobromic acid, where the hydroxyl group is replaced by a bromine atom.
The reaction is an SN1 mechanism, particularly favorable for secondary alcohols like isopropyl alcohol.
Reaction:
(CH3)2CHOH+HBr→(CH3)2CHBr+H2O
The hydroxyl group is protonated by the acid.
A water molecule is eliminated, forming a carbocation intermediate.
Bromide ion then attacks the carbocation, forming 2-Bromopropane.
This is an efficient, cost-effective method suitable for bulk production, but 2-Bromopropane may lead to side products under uncontrolled conditions.
PBr3 Method (Phosphorus Tribromide):
For laboratory-scale or high-purity synthesis, phosphorus tribromide (PBr3) is used as a brominating agent.
2-Bromopropane reacts cleanly with alcohols and avoids harsh acidic conditions.
Reaction:
3(CH3)2CHOH+PBr3→3(CH3)2CHBr+H3PO3
This reaction is generally carried out in anhydrous conditions at low temperatures.
2-Bromopropane proceeds via an SN2 mechanism, minimizing rearrangement and side reactions.
Red Phosphorus + Bromine Method:
An alternative synthesis involves red phosphorus and bromine, which together generate PBr3 in situ, which then reacts with the alcohol:
Step 1 (in situ):
2P+3Br2→2PBr3
Step 2:
PBr3+3(CH3)2CHOH→3(CH3)2CHBr+H3PO3
This method is versatile and can be adapted depending on scale and availability of reagents.
History of 2-Bromopropane:
2-Bromopropane, has its roots in the early developments of organohalide chemistry during the 19th century.
2-Bromopropane was first synthesized in the mid-to-late 1800s, as chemists began systematically exploring the substitution of hydroxyl groups in alcohols with halogens like bromine and chlorine.
This period marked the rapid expansion of organic chemistry, where the behavior of alcohols and their halogenated derivatives became a foundational area of study.
The synthesis of 2-Bromopropane likely followed the discovery of hydrobromic acid’s ability to react with secondary alcohols, a method that became a classical route for preparing alkyl halides.
As laboratories refined techniques for purifying and analyzing organic compounds, 2-Bromopropane’s structure was confirmed and distinguished from its isomeric counterparts.
By the early 20th century, 2-Bromopropane was being produced more systematically for use in research and chemical manufacturing, especially as a building block in synthetic organic chemistry.
2-Bromopropane's utility as an alkylating agent, especially in SN2 and SN1 mechanisms, made it an important reagent in the synthesis of pharmaceuticals and agricultural chemicals.
In modern times, 2-Bromopropane's relevance continues in both academic and industrial settings, although its production and handling are now governed by stricter safety and environmental regulations due to concerns about toxicity and flammability.
Today, 2-Bromopropane remains a staple in laboratories for its reactivity, accessibility, and versatility, making it a useful reference point in the history and practice of synthetic chemistry.
Handling and Storage of 2-Bromopropane:
Handle in a well-ventilated area or under a fume hood to avoid inhalation of vapors.
Avoid contact with skin, eyes, and clothing.
Use proper PPE (gloves, goggles, lab coat).
Keep away from heat sources, sparks, flames, and static discharge — 2-Bromopropane is highly flammable.
Store in a tightly sealed container in a cool, dry, and well-ventilated area, away from oxidizing agents and moisture.
Use only non-sparking tools and explosion-proof equipment when handling.
Reactivity and Stability of 2-Bromopropane:
Chemically stable under recommended storage conditions.
Reacts with strong oxidizers, alkalis, and moisture.
Incompatible with strong bases, amines, and active metals (e.g., sodium, potassium).
May decompose upon heating to release toxic fumes including hydrogen bromide (HBr) and carbon oxides.
Avoid prolonged exposure to light, air, or heat which may initiate decomposition.
First Aid Measures of 2-Bromopropane:
Inhalation:
Move the person to fresh air.
If breathing is difficult, give oxygen and seek medical attention.
Skin Contact:
Immediately wash with soap and plenty of water for at least 15 minutes.
Remove contaminated clothing.
Seek medical attention if irritation persists.
Eye Contact:
Rinse cautiously with water for at least 15 minutes, lifting eyelids.
Seek immediate medical attention.
Ingestion:
Do not induce vomiting.
Rinse mouth with water and get medical help immediately.
Firefighting Measures of 2-Bromopropane:
Flammable liquid; may form explosive mixtures with air.
Suitable extinguishing media:
Carbon dioxide (CO₂), dry chemical powder, or foam.
Water may be ineffective on flames but can be used to cool exposed containers.
Fire may produce irritating and toxic vapors such as hydrogen bromide and carbon monoxide.
Firefighters should wear self-contained breathing apparatus (SCBA) and full protective gear.
Accidental Release Measures of 2-Bromopropane:
Evacuate area and ensure proper ventilation.
Eliminate all sources of ignition.
Wear PPE including chemical-resistant gloves, goggles, and protective clothing.
Use inert absorbent material (e.g., vermiculite, sand) to contain and absorb the spill.
Place collected material in properly labeled containers for disposal according to local regulations.
Do not allow to enter drains or watercourses.
Exposure Controls / Personal Protective Equipment of 2-Bromopropane:
Engineering Controls:
Use fume hoods or explosion-proof ventilation systems.
Eye Protection:
Safety goggles or face shield.
Skin Protection:
Chemical-resistant gloves (e.g., nitrile or neoprene) and lab coat.
Respiratory Protection:
If ventilation is inadequate, use a NIOSH-approved respirator for organic vapors.
Hygiene Measures:
Wash hands and face thoroughly after handling.
Remove contaminated clothing immediately.
Identifiers of 2-Bromopropane:
CAS Number: 75-26-3
Beilstein Reference: 741852
ChEMBL: ChEMBL451810
ChemSpider: 6118
ECHA InfoCard: 100.000.778
EC Number: 200-855-1
PubChem CID: 6358
RTECS number: TX4111000
UNII: R651XOV97Z
UN number: 2344
CompTox Dashboard (EPA): DTXSID7030197
InChI: InChI=1S/C3H7Br/c1-3(2)4/h3H,1-2H3
Key: NAMYKGVDVNBCFQ-UHFFFAOYSA-N
SMILES: CC(C)Br
Chemical Formula: C₃H₇Br
Molecular Weight: 122.99 g/mol
CAS Number: 75-26-3
EC Number: 200-855-9
PubChem CID: 6368
UN Number: 2344
InChI: InChI=1S/C3H7Br/c1-3(2)4/h3H,1-2H3
InChI Key: NNQLCJMGKPLQHF-UHFFFAOYSA-N
SMILES Notation: CC(C)Br
Properties of 2-Bromopropane:
Chemical formula: C3H7Br
Molar mass: 122.993 g·mol−1
Appearance: Colorless liquid
Density: 1.31 g mL−1
Melting point: −89.0 °C; −128.1 °F; 184.2 K
Boiling point: 59 to 61 °C; 138 to 142 °F; 332 to 334 K
Solubility in water: 3.2 g L−1 (at 20 °C)
log P: 2.136
Vapor pressure: 32 kPa (at 20 °C)
Henry's law constant (kH): 1.0 μmol Pa−1 mol−1
Refractive index (nD): 1.4251
Viscosity: 0.4894 mPa s (at 20 °C)
Molecular Weight: 122.99
XLogP3-AA: 1.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0
Exact Mass: 121.97311
Monoisotopic Mass: 121.97311
Topological Polar Surface Area: 0 Ų
Heavy Atom Count: 4
Complexity: 10.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Quality Level: 200
Assay: 99%
Form: liquid
Refractive index: n20/D 1.425 (lit.)
bp: 59 °C (lit.)
mp: −89 °C (lit.)
Density: 1.31 g/mL at 25 °C (lit.)
SMILES string: CC(C)Br
InChI: 1S/C3H7Br/c1-3(2)4/h3H,1-2H3
InChI key: NAMYKGVDVNBCFQ-UHFFFAOYSA-N
Thermochemistry of 2-Bromopropane:
Heat capacity (C): 135.6 J K mol−1
Std enthalpy of formation (ΔfH⦵298): −129 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.0537–−2.0501 MJ mol−1
Specifications of 2-Bromopropane:
Appearance (Clarity): Clear
Appearance (Colour):Colourless to pale yellow
Appearance (Form): Liquid
Colour (APHA): max. 30
Assay (GC): min. 99%
Density (g/ml) @ 20°C: 1.305-1.315
Refractive Index (20°C): 1.424-1.425
Boiling Range: 58-60°C
Stabilizer (Ag wire): Present
Related Products of 2-Bromopropane:
1-(3,5-dichloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
1,3-dimethyl-1H,4H,5H,6H-pyrazolo[3,4-b][1,4]thiazin-5-one
2-(3,5-dichlorophenyl)-2-(ethylamino)acetic acid hydrochloride
6,7-dichloro-2-methyl-2,3-dihydro-1-benzofuran-3-one
2-{[(3,4-dichlorophenyl)carbamoyl]amino}-3-(1H-indol-3-yl)propanoic acid
Related compounds of 2-Bromopropane:
Related alkanes:
Bromoethane
1-Bromopropane
tert-Butyl bromide
1-Bromobutane
2-Bromobutane
Names of 2-Bromopropane:
Preferred IUPAC name:
2-Bromopropane
Other name:
Isopropyl bromide
