ELLAGIC ACID
Ellagic acid is a potent skincare ingredient derived from raspberry fruit cells, celebrated for its antioxidant, anti-inflammatory, and skin-rejuvenating properties.
Packed with ellagic acid, vitamin C, and essential fatty acids, Ellagic acid helps to protect the skin from environmental damage, particularly UV-induced free radicals, which can accelerate aging.
Known for its moisturizing properties, Ellagic acid helps maintain hydration by forming a barrier that locks in moisture, resulting in smoother, softer skin.
Synonyms: Raspberry Fruit Extract, Rubus Idaeus Extract, Raspberry Extract, Raspberry Cell Extract, Raspberry Seed Extract, Raspberry Bioactive Extract, Raspberry Essence, Raspberry Phytoextract, Raspberry Oil, Red Raspberry Extract, Raspberry Concentrate, Raspberry Juice Extract, Raspberry Pulp Extract, Raspberry Puree, Raspberry Infusion, Raspberry Powder, Raspberry Active Extract, Raspberry Phytochemical Extract, Natural Raspberry Extract, Raspberry Antioxidant Extract, Raspberry Skin Extract, Raspberry Leaf Extract, Rubus Extract, Berry Extract, Fruit Cell Extract, Botanical Raspberry Extract, Raspberry Essence Oil, Cold-Pressed Raspberry Extract, Whole Fruit Extract, Raspberry Flavor Extract, Nutrient-Rich Raspberry Extract, Raspberry Phytosubstance, Raspberry Enzyme Extract, Raspberry Plant Extract, Raspberry Bioextract, Red Berry Extract, Raspberry Hydrosol, Raspberry Superfruit Extract, Raspberry Concentrated Extract, Raspberry Seed Oil, Raspberry Antimicrobial Extract, Raspberry Phytomolecule, Raspberry Cellular Oil, Raspberry Antioxidant Oil, Raspberry Cosmetic Extract, Raspberry Nutraceutical Extract, Raspberry Essence Concentrate, Raspberry Botanical Extract, Raspberry Tincture, Raspberry Whole Plant Extract
Ellagic acid delivers the natural molecules this botanical species can offer in a water-soluble format, including tetrahydroxy flavone, flavone glycoside, gallic acid (GA), ellagic acid(EA), flavonoid glycosides, phenolics, organic acids, and amino acids, to power your products naturally.
Explore the Ellagic acid's unique synergy between its compounds delivers a powerhouse of natural ingredients to consider for haircare, blemished skin conditions, hydration, premature aging and more along with beautiful new imagery to create unique content for your brand.
Ellagic acid, also known as the Small-leafed Bramble, is native to the Eastern coast of Australia, widespread through the eucalyptus woodland, well away from the rainforest.
The berries were eaten raw by the Indigenous Australians as the red berries have a very similar taste to that of the commercially grown raspberries.
Ellagic acid is also used in sauces and jams.
Now the Ellagic acid has naturalised in Japan, China, Taiwan and Vietnam.
The dried fruit are used in traditional Chinese medicine.
Delivering True to Nature hydrophilic plant profiles, Cellular Extraction harnesses a species' water-soluble blueprint of phyto-compounds and their derivatives (which we call the entourage) suspended in a liquid medium.
Extracted rapidly under high pressure, we capture the natural molecules.
Committed to conscious manufacturing, Cellular Extracts are created using purified, deionised rain-harvested water, and less plant material to produce a True to Nature extract.
With attention to eco-responsible practices, traceable to source and transparent in composition - Cellular Extracts deliver the brilliance of nature.
Ellagic acid, often referred to as raspberry cell extract, is a bioactive ingredient derived from raspberry fruit cells.
Ellagic acid is rich in vitamins (like vitamin C), antioxidants, and essential fatty acids, making it popular in skincare and cosmetic formulations.
Known for its anti-aging, anti-inflammatory, and skin-brightening properties, Ellagic acid helps protect the skin from environmental damage, promotes collagen production, and can aid in reducing signs of aging like fine lines and wrinkles.
Ellagic acid is also valued for its ability to hydrate and nourish the skin without causing irritation, suitable for sensitive skin types.
As reported in literature by other researchers, several raspberry varieties belonging to the genuses Rubus, Fragaria, Vaccinium, Ribes, Aronia and Sorbus contain bioactive compounds that are able to attenuate skin inflammation and reduce the damage caused by reactive oxidative agents.
Indeed, a wide spectrum of anthocyanins are present in raspberry extracts and have been associated with anti-inflammatory activity; Ellagic acids also contain vitamin C and phenolics, which have a high free radical scavenging capacity.
Moreover Ellagic acid, which upon hydrolysis release ellagic acid, conferring antiviral properties and protection against certain forms of cancer.
Finally, Ellagic acids include the important compound resveratrol, a polyphenol whose activity has been linked to anticarcinogenic effects and the regulation of low-density lipoproteins, mediated by sirtuin activation.
Among all the Rubus species analyzed, the wild red raspberry variety Rubus idaeus contained the highest number of anthocyanins and highest level of antioxidant compounds.
Based on these characteristics, the authors chose wild red raspberry as the source of stem cells to develop a new cosmetic active ingredient.
The leaves of this plant were used as starting material to produce stem cells, whose extract had interesting cosmetic applications.
Rubus idaeus, or raspberries as we know them, are a member of the rose family.
First cultivated in the Middle Ages, they gained popularity in the 20th century for use in pharmaceuticals, fragrances and liquors.
We particularly love Ellagic acid for its hydrating and nutritious properties, which have been shown to help maintain healthy skin and hair.
Ellagic acid is a potent skincare ingredient derived from raspberry fruit cells, celebrated for its antioxidant, anti-inflammatory, and skin-rejuvenating properties.
Packed with ellagic acid, vitamin C, and essential fatty acids, its helps to protect the skin from environmental damage, particularly UV-induced free radicals, which can accelerate aging.
This antioxidant-rich extract aids in reducing fine lines and wrinkles by boosting collagen production and supporting skin elasticity.
Additionally, Ellagic acid's anti-inflammatory qualities make it suitable for sensitive and redness-prone skin, providing soothing relief.
The high vitamin C content in Ellagic acid contributes to a brighter, more even complexion by reducing hyperpigmentation and enhancing radiance.
Known for its moisturizing properties, Ellagic acid helps maintain hydration by forming a barrier that locks in moisture, resulting in smoother, softer skin.
Often used in serums, moisturizers, and facial oils, Ellagic acid is a popular choice in natural and sustainable skincare products that target concerns like aging, dullness, and uneven skin tone, delivering both protective and restorative benefits.
Ellagic acid is increasingly valued in skincare for its comprehensive anti-aging and protective benefits.
Ellagic acid contains is particularly effective at preventing collagen degradation, a major cause of skin sagging and wrinkle formation.
By preserving collagen and enhancing its synthesis through its high vitamin C content, Ellagic acid helps the skin maintain firmness and elasticity over time.
Additionally, Ellagic acid's anti-inflammatory properties extend beyond soothing redness; they also play a role in calming conditions like eczema and rosacea, making Ellagic acid a versatile option for those with sensitive skin concerns.
Another remarkable aspect of Ellagic acid is its photoprotective quality.
While Ellagic acid does not replace sunscreen, it assists in repairing skin that has been exposed to UV radiation, helping to mitigate oxidative damage and prevent further harm.
This photoprotective effect, combined with Ellagic acid's ability to even out skin tone and reduce hyperpigmentation, makes it ideal for achieving a brighter, healthier complexion.
Beyond facial care, Ellagic acid is also used in hair products, where its moisturizing and protective qualities benefit both the scalp and hair strands.
In haircare, Ellagic acid can reduce dryness and add shine, supporting overall hair vitality.
Ellagic acid's fatty acids form a light barrier that not only retains moisture but also protects against environmental aggressors, making it a versatile ingredient across personal care products.
Sustainably sourced and often found in eco-conscious formulations, Ellagic acid appeals to those looking for natural, effective solutions for skin and hair care.
Ellagic acid's multifaceted benefits, from hydration and anti-aging effects to skin tone correction and protection, have made it a popular choice in modern skincare aimed at holistic, long-term skin health.
Uses of Ellagic acid:
Ellagic acid is a versatile ingredient widely used in skincare and haircare for its nourishing, protective, and rejuvenating qualities.
Packed with antioxidants like ellagic acid and vitamin C, it is particularly valued in anti-aging and brightening products, where it helps to boost collagen production, smooth fine lines, and even out skin tone.
Ellagic acid's high content of fatty acids provides hydration and forms a barrier that locks in moisture, making it a staple in moisturizers, serums, and masks aimed at keeping the skin soft, plump, and smooth.
Additionally, Ellagic acid's anti-inflammatory properties make it an excellent choice for sensitive skin, as it calms irritation and reduces redness.
Ellagic acid is also popular in after-sun treatments due to its ability to support the skin in repairing UV damage, though it doesn’t replace sunscreen.
Beyond skincare, Ellagic acid is used in hair products like conditioners and scalp treatments, where it hydrates the scalp, strengthens hair strands, and adds shine.
Often found in eco-friendly formulations, Ellagic acid aligns with clean beauty principles, making it a top choice for those seeking natural, sustainable, and effective solutions for both skin and hair health.
Ellagic acid has a broad range of applications in skincare and haircare due to its antioxidant, anti-inflammatory, and hydrating properties.
Here’s a look at Ellagic acid's primary uses:
Anti-Aging Skincare:
Found in serums, creams, and anti-aging treatments, Ellagic acid supports collagen production, reduces fine lines, and combats signs of aging through its rich antioxidant content.
Brightening Products:
Ellagic acid’s high vitamin C content makes it ideal for brightening serums and creams, as it helps even out skin tone, reduce hyperpigmentation, and add radiance.
Hydrating and Soothing Formulations:
Ellagic acid is used in moisturizers, lotions, and masks, Ellagic acid provides hydration and helps soothe sensitive, inflamed, or redness-prone skin.
Ellagic acid's fatty acids aid in moisture retention, making it effective in keeping skin soft and smooth.
Sun Damage Repair:
While not a substitute for sunscreen, Ellagic acid is included in after-sun treatments and repair serums for its ability to help counteract oxidative stress from UV exposure, promoting healthier, less damaged skin.
Sensitive Skin Products:
Due to Ellagic acid's anti-inflammatory effects, it’s often found in products designed for sensitive or reactive skin, where it helps reduce redness and calm irritation.
Haircare Applications:
In hair products like conditioners, scalp treatments, and oils, Ellagic acid moisturizes the scalp, strengthens hair, and adds shine.
Ellagic acid's antioxidant properties also protect hair from environmental stressors.
Eco-Friendly and Natural Formulations:
Ellagic acid is a favorite in clean beauty and natural skincare formulations.
It’s often included in eco-friendly product lines that focus on sustainability and minimal environmental impact.
In essence, Ellagic acid’s versatility allows it to address various skin concerns, from dryness and dullness to aging and sensitivity, making it a valuable ingredient in holistic skincare and haircare routines.
Benefits of Ellagic acid:
Ellagic acid offers a range of benefits for skin and hair due to its rich blend of antioxidants, vitamins, and essential fatty acids.
Here are some of Ellagic acid's key advantages:
Anti-Aging Effects:
Ellagic acid's vitamin C protect against free radical damage, prevent collagen breakdown, and reduce fine lines and wrinkles, keeping skin firm and youthful.
Brightening and Even Skin Tone:
Vitamin C in Ellagic acid helps fade dark spots, reduces hyperpigmentation, and brightens the complexion, giving skin a healthy glow.
Hydration and Moisture Retention:
The fatty acids in Ellagic acid form a barrier on the skin, locking in moisture to keep skin hydrated, smooth, and soft.
Anti-Inflammatory Relief:
Ellagic acid's anti-inflammatory properties soothe irritated or sensitive skin, reduce redness, and provide relief for conditions like eczema and rosacea.
Sun Damage Repair:
While not a sunscreen, Ellagic acid helps repair UV damage and supports skin healing after sun exposure, minimizing the harmful effects of environmental stressors.
Scalp and Hair Health:
When used in haircare, Ellagic acid nourishes the scalp, strengthens hair strands, and adds shine, improving overall hair vitality.
Eco-Friendly and Natural:
Often sustainably sourced, Ellagic acid is popular in clean beauty formulations, appealing to those looking for natural and environmentally conscious skincare and haircare options.
Science of Ellagic acid:
Ellagic acid is made of 83% fatty acids that help to upkeep skin’s health by assisting the epidermis in repairing damage, retaining moisture, and remaining resistant to daily stressors.
The same is true of your scalp and Ellagic acid contributes to keeping Ellagic acid conditioned which can alleviate dandruff, itching, and dryness.
Along with other nutrients such as thiamin and riboflavin, raspberries boast a high level of vitamins C and E, which are both known to reduce early signs of aging such as fine lines, wrinkles, and discoloration.
They’ve also been shown to boost collagen production and help both the skin and hair regain elasticity.
Ellagic acid is perhaps best known for its hydrating properties.
Ellagic acid contains phytosterols – antioxidants that help attract and retain moisture.
When applied to hair, Ellagic acid’s ability to deeply hydrate is super-effective at reducing frizz and flyaways, leaving hair more manageable and smooth.
Extract Preparation of Ellagic acid:
A stem cell extract was prepared as described below, starting from the leaves of wild red raspberry since they showed the highest antioxidant content of all the plant organs.
This is because pigments and other antioxidant molecules involved in photosynthesis are only present in the leaves.
Cultured stem cells were produced in a laboratory to closely control growth conditions and to limit contaminants and other biological pathogens such as viruses and bacteria.
Preparing a product from sterile cultured cells standardizes the protocol, guaranteeing a reproducible yield from each batch and the desired characteristics of quality.
Cosmetic active ingredients obtained from any raspberry plant organ exhibit variations in the content and quality of beneficial phenolics, anthocyanins and flavonoids, compared with the controlled stem cells that are consistent in content.
The content and quality of these compounds also are dependent upon the fruit variety and even the age of the plant used.
Moreover, the presence of contaminants and pollutants in the fruits, such as heavy metals, pesticides, mycotoxins, etc., may alter the quality of the product.
Thus, the use of cultured raspberry stem cells to obtain the soluble extract also controls health risks to consumers.
Preparation protocol:
Rubus idaeus leaves were surface sterilized in 70% EtOH for 15 min and 1% bleach for an additional 15 min, then washed three times with sterile water.
The leaf explants were each cut into 0.5-cm pieces, wounded with a scalpel blade, and placed on medium AB1a supplemented with 500mg/L myo-inositol, 30mg/L sucrose, 1 mg/L of 2,4-Dichlorophenoxyacetic acid (2,4-D), 0.1mg/L kinetin, 1mg/L adenine and 7.5mg/L plant agar for callus induction.
White and friable callus was obtained after five weeks of cultivation in the dark.
The callus cultures were maintained by transferring the tissues onto fresh AB1a medium every four weeks.
To initiate stem cell liquid culture, 50 mg of 40–45-day-old-callus were resuspended in 25–30 mL AB1a liquid medium.
The culture was incubated at 27°C in the dark under constant orbital stirring (110 rpm).
The callus tissue gradually disintegrated and formed single cells or small cell aggregates after 10 days.
The suspensions were then transferred into a larger volume, where 50 mL of a dense culture was used as the starting material to inoculate 1 L of culture medium.
After seven days, the cells were collected and filtered through a layer of Miracloth fabricb.
The drained cells (approx. 300 g) were then resuspended in 300 mL of PBS (136 mM NaCl, 2.7 mM KCl, 12 mM NaH2PO4 and 1.76 mM KH2PO4, pH 7.4) and homogenized in a mortar.
The resulting lysate was centrifuged at 10,000 rpm to precipitate the particulate fraction and isolate the soluble components.
The supernatant was then collected and lyophilized and the powder obtained (approx. 4 g) was dissolved in water at the required concentrations.
Handling and Storage of Ellagic acid:
Handling:
Use appropriate personal protective equipment (PPE) when handling Ellagic acid, such as gloves and safety glasses.
Avoid direct contact with skin and eyes.
Work in a well-ventilated area to minimize inhalation exposure.
Storage:
Store in a cool, dry place away from direct sunlight and heat sources.
Keep containers tightly sealed when not in use to prevent contamination and evaporation.
Ensure the storage area is clean and free from incompatible materials.
Stability and Reactivity of Ellagic acid:
Stability:
Ellagic acid is generally stable under recommended storage conditions (cool, dry, dark environment).
Reactivity:
Avoid exposure to strong oxidizing agents and extreme temperatures.
No hazardous polymerization will occur.
May degrade when exposed to excessive heat, light, or moisture.
First Aid Measures of Ellagic acid:
Inhalation:
If inhaled, move to fresh air.
If symptoms persist, seek medical attention.
Skin Contact:
Wash affected area with soap and water.
If irritation persists, seek medical advice.
Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do.
Continue rinsing and seek medical attention if irritation occurs.
Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek medical attention if symptoms develop.
Firefighting Measures of Ellagic acid:
Suitable Extinguishing Media:
Use water spray, foam, dry chemical, or carbon dioxide (CO₂) to extinguish fires.
Specific Hazards:
In case of combustion, carbon oxides and other hazardous fumes may be released.
Protective Equipment:
Wear self-contained breathing apparatus (SCBA) and full protective gear when fighting fires involving this material.
Accidental Release Measures of Ellagic acid:
Personal Precautions:
Wear appropriate PPE (gloves, goggles) to avoid contact with skin and eyes.
Environmental Precautions:
Prevent spills from entering water sources or drainage systems.
Containment and Cleanup:
Absorb spill with inert material (e.g., sand, earth).
Collect the material in a suitable container for disposal.
Clean the affected area thoroughly.
Exposure Controls/Personal Protective Equipment of Ellagic acid:
Exposure Limits:
Follow local regulatory guidelines for permissible exposure limits.
Engineering Controls:
Use local exhaust ventilation if necessary to maintain safe air quality.
PPE Recommendations:
Eye Protection:
Safety glasses or goggles to prevent eye contact.
Skin Protection:
Gloves (nitrile or latex) to minimize skin exposure.
Respiratory Protection:
If adequate ventilation cannot be ensured, use a suitable respirator.
Identifiers of Ellagic acid:
INCI Monograph ID: 11763
INCI: Rubus parvifolius Fruit Extract
Specifications of Ellagic acid:
Appearance: Clear to light amber or slightly pinkish liquid.
Odor: Mild, fruity scent reminiscent of fresh raspberries.
Solubility: Water-soluble; may also have oil-soluble variants.
pH: Typically ranges from 4.0 to 6.0, depending on the formulation and extraction method.
Active Components:
Ellagic Acid: 0.5 - 2% (varies with extraction).
Vitamin C (Ascorbic Acid): Varies based on the source and extraction.
Anthocyanins: Responsible for the color and antioxidant properties.
Essential Fatty Acids: Include linoleic and alpha-linolenic acids.
