DISODIUM COCOAMPHODIACETATE
Disodium cocoamphodiacetate is a mild amphoteric surfactant derived from coconut oil, commonly used in personal care and cosmetic formulations due to its excellent cleansing, foaming, and conditioning properties.
Disodium cocoamphodiacetate’s biodegradability and mild nature make it a preferred choice for eco-friendly and sulfate-free formulations, providing effective cleansing without stripping natural oils.
Disodium cocoamphodiacetate’s amphoteric nature allows it to be compatible with anionic, cationic, and nonionic surfactants, making it a versatile ingredient in complex formulations.
CAS Number: 68650-39-5
EC Number: 272-125-9
Chemical Formula: C20H38N2Na2O6
Molecular Weight: 460-500 g/mol
Synoynms: Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts, Disodium cocoamphodiacetate, Imidazolium compounds, 1-2-(carboxymethoxy)ethyl-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts, Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4 ,5-dihydro-2-norco- co alkyl, hydroxides, disodium salts, COCOAMPHOCARBOXYGLYCINATE, Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt, Imidazolium compounds, 1-[2-(carboxymethoxy) Coconut alkyl-1-(2-hydroxyethyl)-2-imidazoline, reaction product with sodium chloroacetate, Amphoterge(R) W-2, DSCADA, Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide, Cocoamphocarboxyglycinate oxide, Disodium cocoamphodiacetate, Cocoamphocarboxyglycinate, Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt, Cocoamphocarboxyglycinate, disodium salt, Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts, Disodium cocoamphodiacetate, 68650-39-5, AMPHOLAK XCO-30, AMPHOSOL 2C, COCOAMPHOCARBOXYGLYCINATE, COCOAMPHODIACETATE [VANDF], CRODATERIC CDA 40, Disodium cocoamphodiacetate [II], DISODIUM N-COCOYL-N-CARBOXYMETHOXYETHYL-N-CARBOXYMETHYLETHYLENEDIAMINE, EMPIGEN CDR40, MACKAM 2C
Disodium cocoamphodiacetate is a mild, amphoteric surfactant derived from coconut oil.
Disodium cocoamphodiacetate is commonly used in personal care and cosmetic formulations due to its excellent cleansing, foaming, and conditioning properties.
Disodium cocoamphodiacetate is particularly valued for its ability to reduce the harshness of other surfactants, making it ideal for sensitive skin and baby care products.
Disodium cocoamphodiacetate works by breaking down oils and dirt on the skin and hair while maintaining moisture balance, preventing excessive dryness or irritation.
Disodium cocoamphodiacetate is also known for its ability to enhance the stability of formulations and improve the texture and feel of products such as shampoos, facial cleansers, body washes, and hand soaps.
Disodium cocoamphodiacetate has good compatibility with anionic, nonionic, and cationic surfactants, allowing it to be used in a wide variety of formulations.
Additionally, Disodium cocoamphodiacetate helps boost foam formation, making products feel richer and more luxurious while still being gentle on the skin and eyes.
Disodium cocoamphodiacetate's biodegradability and mild nature make it a preferred choice for eco-friendly and sulfate-free formulations, as it provides effective cleansing without stripping natural oils.
Moreover, Disodium cocoamphodiacetate contributes to the overall mildness of cleansing products, helping to reduce irritation potential, which is why it is often found in formulations designed for individuals with sensitive skin or scalp conditions.
Due to Disodium cocoamphodiacetate's versatility and skin-friendly nature, it is widely used in both.
Disodium cocoamphodiacetate is a clear yellow liquid with mild characteristic odor.
Disodium cocoamphodiacetate is derived from coconut.
Disodium cocoamphodiacetate is made from fatty acids from coconut oil, also called coconut acid.
Disodium cocoamphodiacetate is a concentrated, mild amphoteric surfactant for hair and skin cleansing products.
Disodium cocoamphodiacetate is also preservative-free.
Disodium cocoamphodiacetate is one of the mildest amphoteric surfactants of its class.
Disodium cocoamphodiacetate is a thick Viscous liquid.
Disodium cocoamphodiacetate is an amphoteric surfactant and contains 20-40% active substance.
Disodium cocoamphodiacetate comes from the fatty acids found in coconut oil.
Disodium cocoamphodiacetate remains stable when stored in a closed, light-protected container in a cool, dry place.
Like many surfactants, Disodium cocoamphodiacetate is originally derived from coconut.
Disodium cocoamphodiacetate is a amphoteric secondary surfactant with high dermatological tolerance, with good foaming and wetting properties even in the presence of salts, oils or in hard water.
This is a preservative-free concentrated solution of natural origins (concentrated solution 45% minimum).
Disodium cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium cocoamphodiacetate is produced by the reaction of cocamidopropyl betaine with diethylenetriamine pentaacetic acid.
Disodium cocoamphodiacetate is made from fatty acids from coconut oil, also called coconut acid.
Disodium cocoamphodiacetate cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.
They also increase foaming capacity or stabilize foams.
Disodium cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.
Disodium cocoamphodiacetate is great for baby products and other non-irritating cleansers.
Disodium cocoamphodiacetate is a surfactant produced on the basis of fatty acids derived from coconut oil.
Disodium cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium cocoamphodiacetate is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Sodium Cocoamphoacetate, Sodium Cocoamphopropionate, Disodium cocoamphodiacetate and Disodium Cocoamphodipropionate are amber liquids with a faint fruity odor.
Disodium cocoamphodiacetate is an amphoteric surfactant commonly used in personal care products.
Disodium cocoamphodiacetate is derived from the fatty acids found in coconut oil.
Disodium cocoamphodiacetate is an imidazoline-derived amphoteric organic compound.
Disodium cocoamphodiacetate is derived from coconut.
Disodium cocoamphodiacetate is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Disodium cocoamphodiacetate is a synthetic amphoteric surfactant routinely used in personal care products.
Disodium cocoamphodiacetate is a gentle, amphoteric surfactant widely used in personal care, household, and industrial cleaning products due to its mild nature and effective cleansing properties.
Derived from coconut oil, this surfactant is known for its ability to create a rich, stable foam while reducing the irritation potential of harsher surfactants like sulfates.
Disodium cocoamphodiacetate is commonly included in shampoos, body washes, facial cleansers, hand soaps, baby care products, and even pet grooming formulations because of its ability to cleanse without stripping the skin or hair of its natural moisture.
Disodium cocoamphodiacetate's amphoteric nature allows it to be compatible with anionic, cationic, and nonionic surfactants, making it a versatile ingredient in complex formulations.
One of Disodium cocoamphodiacetate's standout properties is its ability to reduce surface tension, effectively lifting away dirt, oil, and impurities while leaving the skin and hair feeling soft and conditioned.
Because of its mildness, Disodium cocoamphodiacetate is often used in sulfate-free and hypoallergenic formulations, catering to individuals with sensitive skin, scalp issues, or conditions like eczema and psoriasis.
Additionally, Disodium cocoamphodiacetate's non-stripping action makes it ideal for color-treated hair, as it helps retain dye pigments and prevent fading.
Beyond personal care, Disodium cocoamphodiacetate is valued for its biodegradability, making it an eco-friendly alternative to harsher cleansing agents.
Disodium cocoamphodiacetate's presence in green and sustainable beauty products aligns with the growing demand for mild yet effective surfactants that are safe for both the user and the environment.
Disodium cocoamphodiacetate's conditioning properties also make it useful in 2-in-1 shampoo and conditioner formulations, as well as micellar waters and makeup removers, where it helps to gently cleanse without leaving behind a greasy residue.
Additionally, Disodium cocoamphodiacetate possesses excellent foam-boosting properties, enhancing the texture and luxurious feel of cleansing products.
Unlike traditional sulfates, which can cause excessive dryness or irritation, Disodium cocoamphodiacetate maintains a balanced approach, ensuring a thorough cleanse without disrupting the skin’s natural barrier.
In industrial and household applications, Disodium cocoamphodiacetate is found in mild dishwashing liquids, laundry detergents, and surface cleaners where a non-irritating yet effective surfactant is needed.
Overall, Disodium cocoamphodiacetate is a multifunctional ingredient that balances mildness with efficacy, making it a preferred choice in a wide range of personal care and cleaning formulations.
Disodium cocoamphodiacetate's ability to enhance product texture, boost foaming, improve mildness, and support sulfate-free and eco-conscious formulations ensures its continued use in modern skincare, haircare, and cleansing products.
Uses of Disodium Cocoamphodiacetate:
Disodium cocoamphodiacetate is a Mild Surfactant for Baby Bath Products & Shampoos.
Disodium cocoamphodiacetate is an Extremely mild, amphoteric surfactant which is not defatting to the skin and also does not strip oils from hair.
Disodium cocoamphodiacetate is a moderate foamer and is recommended for sensitive skin, baby skin, facial products.
Disodium cocoamphodiacetate is used for use in shampoos and body wash where optimum foam is desired, combine with another surfactant such as decyl glucoside and/or cocamidopropyl betaine for a mild high-foaming blend.
Disodium cocoamphodiacetate is used for Baby Shampoos a surfactant which is having a quality mild, amphoteric, foaming and cleansing agent that can reduce the overall irritation of products is required.
Disodium cocoamphodiacetate is often used in sensitive skin formulations like baby shampoos, shampoos, bath and shower body washes, and facial products.
Disodium cocoamphodiacetate is compatible with anionic, non-ionic and most cationic systems.
In personal care /skin and hair care this coconut oil-derived surfactant, Disodium cocoamphodiacetate, may be used with another surfactant, such as cocomidopropyl betaine or decyl glucoside to make a gentle foam, high-performance product.
Disodium cocoamphodiacetate is used in many household and industrial applications too.
Disodium cocoamphodiacetate is stable over a broad pH range.
Easy to use Disodium cocoamphodiacetate is great in many applications, including personal care and industrial applications.
Disodium cocoamphodiacetate improves conditioning on skin and hair at acidic pH.
In personal care formulations like bubble baths, shampoos, & body cleansers, Disodium cocoamphodiacetate makes a moderate lather, cleans without defatting the skin, giving a rich, conditioning effect.
Disodium cocoamphodiacetate is stable over a wide pH range which makes it ideal for many personal care, household, and industrial applications.
In addition to personal care products, Disodium cocoamphodiacetate is useful for the formulation of products used around food preparation areas, and high alkaline hard surface cleaners.
Disodium cocoamphodiacetate is a mild detergent cleansing agent derived from coconut; most often used in facial cleansers.
Disodium cocoamphodiacetate is in appearance, a Gold viscous liquid with its pH 8.5 - 9.5 and a Customary Usage: 1% - 50% depending on the final application.
Ideal for use in all types of industrial cleaners etc. since Disodium cocoamphodiacetate aids in flash foaming and improves the foam stability in formulations.
Disodium cocoamphodiacetate is non-toxic and biodegradable.
Disodium cocoamphodiacetate is used creamy detergents for sensitive skin and frizzy hair.
Disodium cocoamphodiacetate is gentle even on mucous tissues and therefore ideal for homemade feminine hygiene detergents.
Disodium cocoamphodiacetate is also recommended for use in baby skin care products.
Disodium cocoamphodiacetate is also used in Premium quality of Shampoos & Face Wash.
Most of the Anionic surfactants such as Sodium laureth Sulfate, Ammonium Laureth Sulfate, Disodium Laureth Sulfosuccinates contains sulfate contents which is harsh in nature.
These surfactants cause damage to hair strands & reduce the moisturisation properties of the shampoo.
Disodium cocoamphodiacetate being amphoteric and having no sulfate content if when used in combination with these anionic surfactants provides excellent results further it also enhances the moisturisation & conditioning properties of the finished shampoo.
Hence, a range of Mild wash & bath products can be formulated with Disodium cocoamphodiacetate such as Baby Bath, Shower Gel, Face Wash, Liquid Hand Wash, 2 in 1 Shampoo Conditioners etc.
Disodium cocoamphodiacetate is also stable & compatible to various other ingredients which are conventionally used in Shampoos.
Disodium cocoamphodiacetate is produced by some renowned organizations which are into complete varieties of surfactants for the cosmetic Industries.
Disodium cocoamphodiacetate is used as a surfactant in many skin and hair care products such as shampoos, body washes, and facial cleansers.
Disodium cocoamphodiacetate has emulsifying properties that make it effective in removing dirt, oil, and other residues from the surface of the skin and hair.
Disodium cocoamphodiacetate is a surfactant commonly used in skin and hair care products.
Disodium cocoamphodiacetate is known for its ability to produce a soft and creamy foam, making it pleasant to use in hair and skin care products.
Additionally, Disodium cocoamphodiacetate is considered safe and effective in cleaning hair and skin without causing irritation or unwanted side effects.
One of the main features of Disodium cocoamphodiacetate is its ability to maintain moisture in the skin and hair.
Disodium cocoamphodiacetate is able to retain the natural moisture of the skin and hair, thus preventing them from becoming dry and brittle.
Disodium cocoamphodiacetate is also used as an ingredient in baby care products due to its gentleness and ability to keep the skin soft and moisturized.
Furthermore, Disodium cocoamphodiacetate is commonly used in products for the care of hospitalized patients, as it is considered safe and effective even for the most sensitive skin.
Disodium cocoamphodiacetate is a surfactant widely used in skin and hair care products due to its emulsifying and moisturizing properties.
Disodium cocoamphodiacetate enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Disodium cocoamphodiacetate is derived from the fatty acids of coconuts and is used as a natural cleanser and conditioner.
Disodium cocoamphodiacetate’s used often in hair products because it is such an effective yet mild cleanser that does not strip the hair of its natural oils.
Disodium cocoamphodiacetate is a surfactant that can be used as an antimicrobial agent.
Disodium cocoamphodiacetate is also a component of the analytical method for measuring fatty acids in plant material.
Disodium cocoamphodiacetate has been shown to have antimicrobial activity against Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa.
Disodium cocoamphodiacetate does not interact with the hydroxyl group of the fatty acid, but reacts with the acidic hydrogen on the carboxyl group, which leads to oxidation and degradation of the molecule.
Disodium cocoamphodiacetate can be used for wastewater treatment and as an oxidation catalyst in organic synthesis.
Disodium cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium cocoamphodiacetate is used Baby baths, mild shampoo, skin cleanser, bubble baths, detergent.
Disodium cocoamphodiacetate works as a mild foaming agent, cleanser, and skin/hair conditioner.
As a foam booster, Disodium cocoamphodiacetate increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.
Disodium cocoamphodiacetate cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.
Disodium cocoamphodiacetate's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.
Disodium cocoamphodiacetate is a mild foaming agent.
Disodium cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.
In cosmetics and personal care products, these four ingredients are used in the formulation of shampoos, and other hair products, and skin cleansing products.
Disodium cocoamphodiacetate used in Antidandruff Shampoo - Very Mild, Baby Body Wash, Conditioning Shampoo - Silicone Free, Facial Cleanser - Soap
Like Feeling, Scalp Treatment Shampoo C-180, Shampoo - Colour Protection C-151, Shower Gel - Ultra Mild C-248, Strengthening Shampoo.
Disodium cocoamphodiacetate’s widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products and so on, as primary or secondary surfactant.
Disodium cocoamphodiacetate is authorized in organic products.
Disodium cocoamphodiacetate is widely used in the preparation of low-irritant shampoo, various facial cleansers, shower gels, pet detergents, facial cleansers and shaving creams, etc.
Recommended dosage of Disodium cocoamphodiacetate: 1.0-10.0%
Disodium cocoamphodiacetate is widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products, as primary or secondary surfactant.
Disodium cocoamphodiacetate plays a crucial role in personal care and cleaning formulations due to its gentle yet effective cleansing properties.
Disodium cocoamphodiacetate creates a rich, stable foam while ensuring mildness, making it a favorite ingredient in shampoos, body washes, and facial cleansers.
Disodium cocoamphodiacetate cleanses without stripping natural oils, making it perfect for sensitive skin and baby care products.
Disodium cocoamphodiacetate enhances sulfate-free shampoos by boosting foam and reducing irritation, helping individuals with scalp sensitivities or color-treated hair.
Disodium cocoamphodiacetate also conditions hair, making it smoother and more manageable.
In skincare, Disodium cocoamphodiacetate gently removes dirt and makeup, leaving the skin soft and hydrated.
Beyond personal care, Disodium cocoamphodiacetate finds its place in household cleaning products.
Disodium cocoamphodiacetate contributes to mild dishwashing liquids, hand soaps, and eco-friendly detergents, ensuring effective cleaning without harming the skin.
Even pet grooming products benefit from Disodium cocoamphodiacetate's tear-free and non-irritating properties.
With its biodegradability and skin-friendly nature, Disodium cocoamphodiacetate continues to be a preferred choice in sustainable, mild, and high-performance cleansing formulations.
Main Uses:
Shampoos & Hand Soap (5% -25%)
Body Wash (5%-30%)
Bubble Bath (10%-30%)
Premoistened Wipes (1%-4%)
Hard Surface Cleaners (1%-3%)
Compatible with anionic, non-ionic and most cationic systems.
Cosmetic Uses:
Cleansing agents
Hair conditioning
Skin conditioning
Surfactants
Surfactant - foam boosting
Surfactant - hydrotrope
Functions of Disodium Cocoamphodiacetate:
Cleansing:
Disodium cocoamphodiacetate helps to keep a clean surface.
Foam boosting:
Disodium cocoamphodiacetate improves the quality of the foam produced by increasing one or more of the following properties: volume, texture and/or stability.
Hair conditioning:
Disodium cocoamphodiacetate leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine.
Hydrotrope:
Disodium cocoamphodiacetate increases the solubility of a substance with low solubility in water.
Skin conditioning:
Disodium cocoamphodiacetate maintains skin in good condition.
Surfactant:
Disodium cocoamphodiacetate reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used.
Disodium cocoamphodiacetate is used in personal care products such as baby shampoos, baby baths, skin cleansers for sensitive skin, shower shampoos, intimate hygiene and liquid soaps.
Benefits of Disodium Cocoamphodiacetate:
Gentle for eyes and skin
Compatible with all surfactants especially cheaper lauryl (ether) sulphates
Preservative free and non-toxic
Excellent foaming even using salt water, in oil or soap
Good resistance to hard water
Characteristics of Disodium Cocoamphodiacetate:
Good compatibility with various surfactants and compatibility with soap bases.
Disodium cocoamphodiacetate is mild to the skin and eyes, and the combination with anions can significantly reduce its irritation.
Good foamability, stable in the range of pH (2-13), not affected by changes in water hardness or pH value; easily biodegradable, with a degradation rate of more than 97%, good safety.
Properties of Disodium Cocoamphodiacetate:
Disodium cocoamphodiacetate acts as a mild foaming agent.
Cleanses the skin without removing the natural oils of the skin.
Disodium cocoamphodiacetate is effective in hair products, it acts as an emollient.
Disodium cocoamphodiacetate helps to improve the look and feel of dry and damaged hair.
Disodium cocoamphodiacetate increases the foaming ability of the products.
Disodium cocoamphodiacetate is a mild non-irritant ingredient, suitable for sensitive skin.
Biodegradability of Disodium Cocoamphodiacetate:
A 2008 study suggested high levels of Disodium cocoamphodiacetate (>216 mg/L) may be toxic to bacteria in wastewater treatment processes.
Results from the 2008 research indicated that Disodium cocoamphodiacetate has limited biodegradability and recalcitrant metabolites may develop.
Production of Disodium Cocoamphodiacetate:
Disodium cocoamphodiacetate is produced through a series of chemical reactions involving coconut-derived fatty acids and other reagents.
The process ensures that the final product is a mild, biodegradable surfactant suitable for personal care and cleaning formulations.
Raw Material Sourcing:
The production begins with coconut oil, which contains fatty acids such as lauric acid.
The primary fatty acid component used is coco-derived amines or amides, which serve as the base for the amphoteric surfactant.
Amidation Reaction:
The coconut oil-derived fatty acids are reacted with amino acids such as glycine or diacetic acid derivatives to form an amide intermediate.
This reaction helps in preparing the molecule for amphoteric surfactant properties.
Quaternization & Neutralization:
The amide intermediate undergoes a chemical reaction with sodium monochloroacetate, leading to the formation of a betainic structure.
Sodium hydroxide (NaOH) is then used to neutralize the reaction, forming the disodium salt of the final surfactant.
Purification & Filtration:
The crude product is filtered and purified to remove any unreacted substances, ensuring high purity and safety.
Water is often added to adjust the final concentration, making the ingredient suitable for formulation use.
Quality Control & Packaging:
The final product undergoes quality checks, including pH testing, viscosity measurement, and stability analysis.
Once approved, Disodium cocoamphodiacetate is packaged in bulk containers or drums and shipped to manufacturers for use in cosmetics, skincare, haircare, and cleaning products.
This process ensures that Disodium cocoamphodiacetate remains a mild, effective, and eco-friendly surfactant, widely used in sulfate-free and sensitive-skin formulations.
History of Disodium Cocoamphodiacetate:
Disodium cocoamphodiacetate has an evolving history rooted in the demand for gentler, more skin-friendly surfactants.
In the early 20th century, traditional soaps and early synthetic surfactants like sodium lauryl sulfate (SLS) dominated the market, but concerns about skin irritation led to the search for milder alternatives.
By the mid-20th century, researchers developed amphoteric surfactants, which balanced cleansing power with mildness, leading to the introduction of compounds like amphodiacetates.
In the 1970s and 1980s, Disodium cocoamphodiacetate emerged as a coconut-derived surfactant that provided effective yet gentle cleansing, making it ideal for baby shampoos, sensitive skin products, and sulfate-free formulations.
As the beauty and personal care industries shifted towards sulfate-free and eco-friendly alternatives in the 1990s and 2000s, this surfactant gained widespread use in shampoos, body washes, and facial cleansers.
With the growing emphasis on sustainability in the 2010s and beyond, Disodium cocoamphodiacetate has become a key ingredient in natural and dermatologist-recommended products due to its biodegradability and compatibility with sensitive skin.
Today, Disodium cocoamphodiacetate remains a preferred choice for gentle cleansing formulations, balancing effectiveness with environmental responsibility.
Handling and Storage of Disodium Cocoamphodiacetate:
Handling:
General Precautions:
Handle with care, ensuring appropriate protective equipment (e.g., gloves, goggles) is used.
Avoid contact with eyes and prolonged skin exposure, although Disodium cocoamphodiacetate is generally non-irritating.
Ensure adequate ventilation in work areas to minimize inhalation risks.
Keep containers tightly closed when not in use to avoid contamination or spills.
Workplace Hygiene:
Wash hands thoroughly after handling.
Avoid ingestion or inhalation of Disodium cocoamphodiacetate.
Do not eat, drink, or smoke in the workplace.
Storage:
Temperature:
Store in a cool, dry place at temperatures between 5°C and 40°C (41°F to 104°F).
Container:
Store in sealed, appropriately labeled containers to prevent contamination.
Separation:
Keep away from incompatible substances, such as strong acids or oxidizing agents.
Avoid direct sunlight exposure to prevent degradation over time.
Stability and Reactivity of Disodium Cocoamphodiacetate:
Stability:
Chemical Stability:
Stable under normal conditions of use and storage.
Stable in aqueous solutions with a pH range of 8.5–10.5.
Decomposition Products:
May produce carbon dioxide (CO₂) and carbon monoxide (CO) when exposed to high temperatures or fires.
Conditions to Avoid:
Extreme heat, open flames, or direct sunlight.
Contact with strong acids, bases, or oxidizing agents may cause degradation or other unwanted reactions.
Reactivity:
Incompatibility:
Avoid contact with strong acids, strong oxidizers, and alkali metals to prevent any exothermic reactions or formation of dangerous products.
Reacts with strong acids to form neutralized compounds that may compromise the integrity of the formulation.
First Aid Measures of Disodium Cocoamphodiacetate:
Inhalation:
Move the person to fresh air immediately.
If symptoms persist (e.g., coughing, difficulty breathing), seek medical attention.
Skin Contact:
Rinse skin with plenty of water.
Remove contaminated clothing and wash before reusing.
If irritation develops, seek medical attention.
Eye Contact:
Rinse eyes immediately with plenty of water for 15–20 minutes, lifting the eyelids occasionally.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth thoroughly with water.
Do not induce vomiting unless directed by medical personnel.
If large quantities are ingested, seek medical attention immediately.
Fire Fighting Measures of Disodium Cocoamphodiacetate:
Suitable Extinguishing Media:
Water fog, foam, dry chemical, or carbon dioxide (CO₂) are suitable for extinguishing fires.
Use fire-fighting measures appropriate to the surrounding materials in the event of a fire.
Specific Hazards in Case of Fire:
Decomposition Products:
In the event of a fire, carbon dioxide (CO₂), carbon monoxide (CO), and other toxic gases may be released.
Wear self-contained breathing apparatus (SCBA) to avoid inhaling fumes.
Protective Equipment:
Firefighters should wear full protective gear, including self-contained breathing apparatus (SCBA), to avoid exposure to hazardous gases.
Accidental Release Measures of Disodium Cocoamphodiacetate:
Personal Precautions:
Avoid Direct Contact:
Wear appropriate personal protective equipment (PPE), including gloves and goggles, to prevent exposure.
Ensure proper ventilation in the affected area to minimize inhalation exposure.
Spill Cleanup:
Containment:
Prevent the spill from spreading by containing it with absorbent materials like sand or diatomaceous earth.
Cleanup:
Use water to dilute the spill, then collect the material using appropriate absorbent materials (e.g., paper towels or cloths).
Dispose of the spilled material according to local regulations.
Environmental Precautions:
Prevent Disodium cocoamphodiacetate from entering drains, sewers, or watercourses.
If contamination occurs, inform local authorities.
Exposure Controls/Personal Protective Equipment of Disodium Cocoamphodiacetate:
Occupational Exposure Limits:
There are no specific exposure limits set for Disodium cocoamphodiacetate.
However, general recommendations for mild surfactants should be followed.
Engineering Controls:
Ensure adequate ventilation in work areas to minimize inhalation exposure.
Use closed systems or local exhaust ventilation when handling large amounts of the substance in industrial settings.
Personal Protective Equipment (PPE):
Respiratory Protection:
Not typically required under normal conditions.
However, use a respirator if airborne concentrations exceed recommended limits.
Hand Protection:
Use protective gloves (e.g., nitrile gloves) to avoid prolonged skin contact.
Eye Protection:
Wear safety goggles or face shields if there is a risk of splashing or direct eye contact.
Skin Protection:
Wear protective clothing to avoid prolonged skin exposure.
Identifiers of Disodium Cocoamphodiacetate:
CAS Number: 68650-39-5
INCI Name: Disodium cocoamphodiacetate
Chemical Formula: C20H38N2Na2O6
EINECS/EC Number: 272-125-9
Molecular Weight: Approximately 460-500 g/mol
Appearance: Clear to pale yellow liquid
Solubility: Water-soluble
pH Range: Approximately 8.5–10.5 (in a 10% aqueous solution)
Synonyms: Cocoamphodiacetate, Disodium Cocoamphodipropionate, Amphoteric surfactant
IUPAC Name: Disodium N-(2-carboxyethyl)-N-(coconut oil alkyl)aminodiacetate
Other Trade Names: Miranol® C2M, Ampholac® 7C, Mackam® 2C, Rewoteric® AM C
HS Code: 3402.90
UNII (FDA Code): 01F2DPE4AO
CAS Number: 68650-39-5
ECHA InfoCard: 100.065.474
EC Number: 272-043-5
UNII: 18L9G3U51M
CompTox Dashboard (EPA): DTXSID9029483
Properties of Disodium Cocoamphodiacetate:
Appearance: Clear to pale yellow liquid
Odor: Mild or nearly odorless
Solubility: Fully soluble in water
Viscosity: Low to moderate
Density: 1.05–1.10 g/cm³
pH Range: 8.5–10.5
Boiling Point: > 100°C
Flash Point: Non-flammable under normal conditions
Boiling Point: 100°C
Melting Point: -12°C
pH: 8.0
Solubility: Soluble in water
Form: Liquid
Physical state: Liquid
Color: Yellow
Odor: Characteristic
Odor Threshold: No data available
pH (As Is): 8
Melting point/range: No data available
Boiling point/boiling range: >100°C
Flash Point: No data available
Flammability: No data available
Auto-ignition temperature: No data available
Water solubility: Soluble
Solubility in other solvents No data available
Partition coefficient (n-Octanol/water): No data available
Vapor Density: > 1
Evaporation rate: > 1
Vapor Pressure (25°C): ~20 mm
Specific Gravity (25°C): 1.17
Specifications of Disodium Cocoamphodiacetate:
Appearance: Clear to pale yellow liquid
Color (Gardner):≤ 5
Odor:Mild or nearly odorless
Viscosity (Brookfield, 25°C):50–1000 cP
Density (25°C):1.05–1.10 g/cm³
Active Content (by weight):30–35%
pH (10% aqueous solution, 25°C):8.5–10.5
Water Content:≤ 5%
Free Alkali (as NaOH):≤ 0.5%
Solubility:Completely soluble in water
Names of Disodium Cocoamphodiacetate:
Regulatory process names:
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
IUPAC names:
3-(tridecyloxy)propanenitrile
3-tridecoxypropanenitrile
Disodium cocoamphodiacetate
Disodium cocoamphodiacetate
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, inner salts, disodium salts
imidazolium compounds, 1-[2-(carboxymethoxy)ethyl}-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hidroxides,sodium salts
Other names:
DSCADA
Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide
Other identifier:
68650-39-5
