COCOAMPHOCARBOXYGLYCINATE OXIDE
Cocoamphocarboxyglycinate oxide is a mild amphoteric surfactant derived from coconut oil, commonly used in personal care and cosmetic formulations due to its excellent cleansing, foaming, and conditioning properties.
Cocoamphocarboxyglycinate oxide’s biodegradability and mild nature make it a preferred choice for eco-friendly and sulfate-free formulations, providing effective cleansing without stripping natural oils.
Cocoamphocarboxyglycinate oxide’s amphoteric nature allows it to be compatible with anionic, cationic, and nonionic surfactants, making it a versatile ingredient in complex formulations.
CAS Number: 68650-39-5
EC Number: 272-125-9
Chemical Formula: C20H38N2Na2O6
Molecular Weight: 460-500 g/mol
Synoynms: Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts, Disodium cocoamphodiacetate, Imidazolium compounds, 1-2-(carboxymethoxy)ethyl-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts, Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4 ,5-dihydro-2-norco- co alkyl, hydroxides, disodium salts, COCOAMPHOCARBOXYGLYCINATE, Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt, Imidazolium compounds, 1-[2-(carboxymethoxy) Coconut alkyl-1-(2-hydroxyethyl)-2-imidazoline, reaction product with sodium chloroacetate, Amphoterge(R) W-2, DSCADA, Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide, Cocoamphocarboxyglycinate oxide, Disodium cocoamphodiacetate, Cocoamphocarboxyglycinate, Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt, Cocoamphocarboxyglycinate, disodium salt, Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts, Disodium cocoamphodiacetate, 68650-39-5, AMPHOLAK XCO-30, AMPHOSOL 2C, COCOAMPHOCARBOXYGLYCINATE, COCOAMPHODIACETATE [VANDF], CRODATERIC CDA 40, Disodium cocoamphodiacetate [II], DISODIUM N-COCOYL-N-CARBOXYMETHOXYETHYL-N-CARBOXYMETHYLETHYLENEDIAMINE, EMPIGEN CDR40, MACKAM 2C
Cocoamphocarboxyglycinate oxide is a mild, amphoteric surfactant derived from coconut oil.
Cocoamphocarboxyglycinate oxide is commonly used in personal care and cosmetic formulations due to its excellent cleansing, foaming, and conditioning properties.
Cocoamphocarboxyglycinate oxide is particularly valued for its ability to reduce the harshness of other surfactants, making it ideal for sensitive skin and baby care products.
Cocoamphocarboxyglycinate oxide works by breaking down oils and dirt on the skin and hair while maintaining moisture balance, preventing excessive dryness or irritation.
Cocoamphocarboxyglycinate oxide is also known for its ability to enhance the stability of formulations and improve the texture and feel of products such as shampoos, facial cleansers, body washes, and hand soaps.
Cocoamphocarboxyglycinate oxide has good compatibility with anionic, nonionic, and cationic surfactants, allowing it to be used in a wide variety of formulations.
Additionally, Cocoamphocarboxyglycinate oxide helps boost foam formation, making products feel richer and more luxurious while still being gentle on the skin and eyes.
Cocoamphocarboxyglycinate oxide's biodegradability and mild nature make it a preferred choice for eco-friendly and sulfate-free formulations, as it provides effective cleansing without stripping natural oils.
Moreover, Cocoamphocarboxyglycinate oxide contributes to the overall mildness of cleansing products, helping to reduce irritation potential, which is why it is often found in formulations designed for individuals with sensitive skin or scalp conditions.
Due to Cocoamphocarboxyglycinate oxide's versatility and skin-friendly nature, it is widely used in both.
Cocoamphocarboxyglycinate oxide is a clear yellow liquid with mild characteristic odor.
Cocoamphocarboxyglycinate oxide is derived from coconut.
Cocoamphocarboxyglycinate oxide is made from fatty acids from coconut oil, also called coconut acid.
Cocoamphocarboxyglycinate oxide is a concentrated, mild amphoteric surfactant for hair and skin cleansing products.
Cocoamphocarboxyglycinate oxide is also preservative-free.
Cocoamphocarboxyglycinate oxide is one of the mildest amphoteric surfactants of its class.
Cocoamphocarboxyglycinate oxide is a thick Viscous liquid.
Cocoamphocarboxyglycinate oxide is an amphoteric surfactant and contains 20-40% active substance.
Cocoamphocarboxyglycinate oxide comes from the fatty acids found in coconut oil.
Cocoamphocarboxyglycinate oxide remains stable when stored in a closed, light-protected container in a cool, dry place.
Like many surfactants, Cocoamphocarboxyglycinate oxide is originally derived from coconut.
Cocoamphocarboxyglycinate oxide is a amphoteric secondary surfactant with high dermatological tolerance, with good foaming and wetting properties even in the presence of salts, oils or in hard water.
This is a preservative-free concentrated solution of natural origins (concentrated solution 45% minimum).
Cocoamphocarboxyglycinate oxide is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Cocoamphocarboxyglycinate oxide also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Cocoamphocarboxyglycinate oxide is produced by the reaction of cocamidopropyl betaine with diethylenetriamine pentaacetic acid.
Cocoamphocarboxyglycinate oxide is made from fatty acids from coconut oil, also called coconut acid.
Cocoamphocarboxyglycinate oxide cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.
They also increase foaming capacity or stabilize foams.
Cocoamphocarboxyglycinate oxide is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Cocoamphocarboxyglycinate oxide increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.
Cocoamphocarboxyglycinate oxide is great for baby products and other non-irritating cleansers.
Cocoamphocarboxyglycinate oxide is a surfactant produced on the basis of fatty acids derived from coconut oil.
Cocoamphocarboxyglycinate oxide is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Cocoamphocarboxyglycinate oxide also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Cocoamphocarboxyglycinate oxide is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Sodium Cocoamphoacetate, Sodium Cocoamphopropionate, Cocoamphocarboxyglycinate oxide and Disodium Cocoamphodipropionate are amber liquids with a faint fruity odor.
Cocoamphocarboxyglycinate oxide is an amphoteric surfactant commonly used in personal care products.
Cocoamphocarboxyglycinate oxide is derived from the fatty acids found in coconut oil.
Cocoamphocarboxyglycinate oxide is an imidazoline-derived amphoteric organic compound.
Cocoamphocarboxyglycinate oxide is derived from coconut.
Cocoamphocarboxyglycinate oxide is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Cocoamphocarboxyglycinate oxide is a synthetic amphoteric surfactant routinely used in personal care products.
Cocoamphocarboxyglycinate oxide is a gentle, amphoteric surfactant widely used in personal care, household, and industrial cleaning products due to its mild nature and effective cleansing properties.
Derived from coconut oil, this surfactant is known for its ability to create a rich, stable foam while reducing the irritation potential of harsher surfactants like sulfates.
Cocoamphocarboxyglycinate oxide is commonly included in shampoos, body washes, facial cleansers, hand soaps, baby care products, and even pet grooming formulations because of its ability to cleanse without stripping the skin or hair of its natural moisture.
Cocoamphocarboxyglycinate oxide's amphoteric nature allows it to be compatible with anionic, cationic, and nonionic surfactants, making it a versatile ingredient in complex formulations.
One of Cocoamphocarboxyglycinate oxide's standout properties is its ability to reduce surface tension, effectively lifting away dirt, oil, and impurities while leaving the skin and hair feeling soft and conditioned.
Because of its mildness, Cocoamphocarboxyglycinate oxide is often used in sulfate-free and hypoallergenic formulations, catering to individuals with sensitive skin, scalp issues, or conditions like eczema and psoriasis.
Additionally, Cocoamphocarboxyglycinate oxide's non-stripping action makes it ideal for color-treated hair, as it helps retain dye pigments and prevent fading.
Beyond personal care, Cocoamphocarboxyglycinate oxide is valued for its biodegradability, making it an eco-friendly alternative to harsher cleansing agents.
Cocoamphocarboxyglycinate oxide's presence in green and sustainable beauty products aligns with the growing demand for mild yet effective surfactants that are safe for both the user and the environment.
Cocoamphocarboxyglycinate oxide's conditioning properties also make it useful in 2-in-1 shampoo and conditioner formulations, as well as micellar waters and makeup removers, where it helps to gently cleanse without leaving behind a greasy residue.
Additionally, Cocoamphocarboxyglycinate oxide possesses excellent foam-boosting properties, enhancing the texture and luxurious feel of cleansing products.
Unlike traditional sulfates, which can cause excessive dryness or irritation, Cocoamphocarboxyglycinate oxide maintains a balanced approach, ensuring a thorough cleanse without disrupting the skin’s natural barrier.
In industrial and household applications, Cocoamphocarboxyglycinate oxide is found in mild dishwashing liquids, laundry detergents, and surface cleaners where a non-irritating yet effective surfactant is needed.
Overall, Cocoamphocarboxyglycinate oxide is a multifunctional ingredient that balances mildness with efficacy, making it a preferred choice in a wide range of personal care and cleaning formulations.
Cocoamphocarboxyglycinate oxide's ability to enhance product texture, boost foaming, improve mildness, and support sulfate-free and eco-conscious formulations ensures its continued use in modern skincare, haircare, and cleansing products.
Uses of Cocoamphocarboxyglycinate Oxide:
Cocoamphocarboxyglycinate oxide is a Mild Surfactant for Baby Bath Products & Shampoos.
Cocoamphocarboxyglycinate oxide is an Extremely mild, amphoteric surfactant which is not defatting to the skin and also does not strip oils from hair.
Cocoamphocarboxyglycinate oxide is a moderate foamer and is recommended for sensitive skin, baby skin, facial products.
Cocoamphocarboxyglycinate oxide is used for use in shampoos and body wash where optimum foam is desired, combine with another surfactant such as decyl glucoside and/or cocamidopropyl betaine for a mild high-foaming blend.
Cocoamphocarboxyglycinate oxide is used for Baby Shampoos a surfactant which is having a quality mild, amphoteric, foaming and cleansing agent that can reduce the overall irritation of products is required.
Cocoamphocarboxyglycinate oxide is often used in sensitive skin formulations like baby shampoos, shampoos, bath and shower body washes, and facial products.
Cocoamphocarboxyglycinate oxide is compatible with anionic, non-ionic and most cationic systems.
In personal care /skin and hair care this coconut oil-derived surfactant, Cocoamphocarboxyglycinate oxide, may be used with another surfactant, such as cocomidopropyl betaine or decyl glucoside to make a gentle foam, high-performance product.
Cocoamphocarboxyglycinate oxide is used in many household and industrial applications too.
Cocoamphocarboxyglycinate oxide is stable over a broad pH range.
Easy to use Cocoamphocarboxyglycinate oxide is great in many applications, including personal care and industrial applications.
Cocoamphocarboxyglycinate oxide improves conditioning on skin and hair at acidic pH.
In personal care formulations like bubble baths, shampoos, & body cleansers, Cocoamphocarboxyglycinate oxide makes a moderate lather, cleans without defatting the skin, giving a rich, conditioning effect.
Cocoamphocarboxyglycinate oxide is stable over a wide pH range which makes it ideal for many personal care, household, and industrial applications.
In addition to personal care products, Cocoamphocarboxyglycinate oxide is useful for the formulation of products used around food preparation areas, and high alkaline hard surface cleaners.
Cocoamphocarboxyglycinate oxide is a mild detergent cleansing agent derived from coconut; most often used in facial cleansers.
Cocoamphocarboxyglycinate oxide is in appearance, a Gold viscous liquid with its pH 8.5 - 9.5 and a Customary Usage: 1% - 50% depending on the final application.
Ideal for use in all types of industrial cleaners etc. since Cocoamphocarboxyglycinate oxide aids in flash foaming and improves the foam stability in formulations.
Cocoamphocarboxyglycinate oxide is non-toxic and biodegradable.
Cocoamphocarboxyglycinate oxide is used creamy detergents for sensitive skin and frizzy hair.
Cocoamphocarboxyglycinate oxide is gentle even on mucous tissues and therefore ideal for homemade feminine hygiene detergents.
Cocoamphocarboxyglycinate oxide is also recommended for use in baby skin care products.
Cocoamphocarboxyglycinate oxide is also used in Premium quality of Shampoos & Face Wash.
Most of the Anionic surfactants such as Sodium laureth Sulfate, Ammonium Laureth Sulfate, Disodium Laureth Sulfosuccinates contains sulfate contents which is harsh in nature.
These surfactants cause damage to hair strands & reduce the moisturisation properties of the shampoo.
Cocoamphocarboxyglycinate oxide being amphoteric and having no sulfate content if when used in combination with these anionic surfactants provides excellent results further it also enhances the moisturisation & conditioning properties of the finished shampoo.
Hence, a range of Mild wash & bath products can be formulated with Cocoamphocarboxyglycinate oxide such as Baby Bath, Shower Gel, Face Wash, Liquid Hand Wash, 2 in 1 Shampoo Conditioners etc.
Cocoamphocarboxyglycinate oxide is also stable & compatible to various other ingredients which are conventionally used in Shampoos.
Cocoamphocarboxyglycinate oxide is produced by some renowned organizations which are into complete varieties of surfactants for the cosmetic Industries.
Cocoamphocarboxyglycinate oxide is used as a surfactant in many skin and hair care products such as shampoos, body washes, and facial cleansers.
Cocoamphocarboxyglycinate oxide has emulsifying properties that make it effective in removing dirt, oil, and other residues from the surface of the skin and hair.
Cocoamphocarboxyglycinate oxide is a surfactant commonly used in skin and hair care products.
Cocoamphocarboxyglycinate oxide is known for its ability to produce a soft and creamy foam, making it pleasant to use in hair and skin care products.
Additionally, Cocoamphocarboxyglycinate oxide is considered safe and effective in cleaning hair and skin without causing irritation or unwanted side effects.
One of the main features of Cocoamphocarboxyglycinate oxide is its ability to maintain moisture in the skin and hair.
Cocoamphocarboxyglycinate oxide is able to retain the natural moisture of the skin and hair, thus preventing them from becoming dry and brittle.
Cocoamphocarboxyglycinate oxide is also used as an ingredient in baby care products due to its gentleness and ability to keep the skin soft and moisturized.
Furthermore, Cocoamphocarboxyglycinate oxide is commonly used in products for the care of hospitalized patients, as it is considered safe and effective even for the most sensitive skin.
Cocoamphocarboxyglycinate oxide is a surfactant widely used in skin and hair care products due to its emulsifying and moisturizing properties.
Cocoamphocarboxyglycinate oxide enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Cocoamphocarboxyglycinate oxide is derived from the fatty acids of coconuts and is used as a natural cleanser and conditioner.
Cocoamphocarboxyglycinate oxide’s used often in hair products because it is such an effective yet mild cleanser that does not strip the hair of its natural oils.
Cocoamphocarboxyglycinate oxide is a surfactant that can be used as an antimicrobial agent.
Cocoamphocarboxyglycinate oxide is also a component of the analytical method for measuring fatty acids in plant material.
Cocoamphocarboxyglycinate oxide has been shown to have antimicrobial activity against Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa.
Cocoamphocarboxyglycinate oxide does not interact with the hydroxyl group of the fatty acid, but reacts with the acidic hydrogen on the carboxyl group, which leads to oxidation and degradation of the molecule.
Cocoamphocarboxyglycinate oxide can be used for wastewater treatment and as an oxidation catalyst in organic synthesis.
Cocoamphocarboxyglycinate oxide is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Cocoamphocarboxyglycinate oxide also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Cocoamphocarboxyglycinate oxide is used Baby baths, mild shampoo, skin cleanser, bubble baths, detergent.
Cocoamphocarboxyglycinate oxide works as a mild foaming agent, cleanser, and skin/hair conditioner.
As a foam booster, Cocoamphocarboxyglycinate oxide increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.
Cocoamphocarboxyglycinate oxide cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.
Cocoamphocarboxyglycinate oxide's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.
Cocoamphocarboxyglycinate oxide is a mild foaming agent.
Cocoamphocarboxyglycinate oxide increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.
In cosmetics and personal care products, these four ingredients are used in the formulation of shampoos, and other hair products, and skin cleansing products.
Cocoamphocarboxyglycinate oxide used in Antidandruff Shampoo - Very Mild, Baby Body Wash, Conditioning Shampoo - Silicone Free, Facial Cleanser - Soap
Like Feeling, Scalp Treatment Shampoo C-180, Shampoo - Colour Protection C-151, Shower Gel - Ultra Mild C-248, Strengthening Shampoo.
Cocoamphocarboxyglycinate oxide’s widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products and so on, as primary or secondary surfactant.
Cocoamphocarboxyglycinate oxide is authorized in organic products.
Cocoamphocarboxyglycinate oxide is widely used in the preparation of low-irritant shampoo, various facial cleansers, shower gels, pet detergents, facial cleansers and shaving creams, etc.
Recommended dosage of Cocoamphocarboxyglycinate Oxide: 1.0-10.0%
Cocoamphocarboxyglycinate oxide is widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products, as primary or secondary surfactant.
Cocoamphocarboxyglycinate oxide plays a crucial role in personal care and cleaning formulations due to its gentle yet effective cleansing properties.
Cocoamphocarboxyglycinate oxide creates a rich, stable foam while ensuring mildness, making it a favorite ingredient in shampoos, body washes, and facial cleansers.
Cocoamphocarboxyglycinate oxide cleanses without stripping natural oils, making it perfect for sensitive skin and baby care products.
Cocoamphocarboxyglycinate oxide enhances sulfate-free shampoos by boosting foam and reducing irritation, helping individuals with scalp sensitivities or color-treated hair.
Cocoamphocarboxyglycinate oxide also conditions hair, making it smoother and more manageable.
In skincare, Cocoamphocarboxyglycinate oxide gently removes dirt and makeup, leaving the skin soft and hydrated.
Beyond personal care, Cocoamphocarboxyglycinate oxide finds its place in household cleaning products.
Cocoamphocarboxyglycinate oxide contributes to mild dishwashing liquids, hand soaps, and eco-friendly detergents, ensuring effective cleaning without harming the skin.
Even pet grooming products benefit from Cocoamphocarboxyglycinate oxide's tear-free and non-irritating properties.
With its biodegradability and skin-friendly nature, Cocoamphocarboxyglycinate oxide continues to be a preferred choice in sustainable, mild, and high-performance cleansing formulations.
Main Uses:
Shampoos & Hand Soap (5% -25%)
Body Wash (5%-30%)
Bubble Bath (10%-30%)
Premoistened Wipes (1%-4%)
Hard Surface Cleaners (1%-3%)
Compatible with anionic, non-ionic and most cationic systems.
Cosmetic Uses:
Cleansing agents
Hair conditioning
Skin conditioning
Surfactants
Surfactant - foam boosting
Surfactant - hydrotrope
Functions of Cocoamphocarboxyglycinate Oxide:
Cleansing:
Cocoamphocarboxyglycinate oxide helps to keep a clean surface.
Foam boosting:
Cocoamphocarboxyglycinate oxide improves the quality of the foam produced by increasing one or more of the following properties: volume, texture and/or stability.
Hair conditioning:
Cocoamphocarboxyglycinate oxide leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine.
Hydrotrope:
Cocoamphocarboxyglycinate oxide increases the solubility of a substance with low solubility in water.
Skin conditioning:
Cocoamphocarboxyglycinate oxide maintains skin in good condition.
Surfactant:
Cocoamphocarboxyglycinate oxide reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used.
Cocoamphocarboxyglycinate oxide is used in personal care products such as baby shampoos, baby baths, skin cleansers for sensitive skin, shower shampoos, intimate hygiene and liquid soaps.
Benefits of Cocoamphocarboxyglycinate Oxide:
Gentle for eyes and skin
Compatible with all surfactants especially cheaper lauryl (ether) sulphates
Preservative free and non-toxic
Excellent foaming even using salt water, in oil or soap
Good resistance to hard water
Characteristics of Cocoamphocarboxyglycinate Oxide:
Good compatibility with various surfactants and compatibility with soap bases.
Cocoamphocarboxyglycinate oxide is mild to the skin and eyes, and the combination with anions can significantly reduce its irritation.
Good foamability, stable in the range of pH (2-13), not affected by changes in water hardness or pH value; easily biodegradable, with a degradation rate of more than 97%, good safety.
Properties of Cocoamphocarboxyglycinate Oxide:
Cocoamphocarboxyglycinate oxide acts as a mild foaming agent.
Cleanses the skin without removing the natural oils of the skin.
Cocoamphocarboxyglycinate oxide is effective in hair products, it acts as an emollient.
Cocoamphocarboxyglycinate oxide helps to improve the look and feel of dry and damaged hair.
Cocoamphocarboxyglycinate oxide increases the foaming ability of the products.
Cocoamphocarboxyglycinate oxide is a mild non-irritant ingredient, suitable for sensitive skin.
Biodegradability of Cocoamphocarboxyglycinate Oxide:
A 2008 study suggested high levels of Cocoamphocarboxyglycinate oxide (>216 mg/L) may be toxic to bacteria in wastewater treatment processes.
Results from the 2008 research indicated that Cocoamphocarboxyglycinate oxide has limited biodegradability and recalcitrant metabolites may develop.
Production of Cocoamphocarboxyglycinate Oxide:
Cocoamphocarboxyglycinate oxide is produced through a series of chemical reactions involving coconut-derived fatty acids and other reagents.
The process ensures that the final product is a mild, biodegradable surfactant suitable for personal care and cleaning formulations.
Raw Material Sourcing:
The production begins with coconut oil, which contains fatty acids such as lauric acid.
The primary fatty acid component used is coco-derived amines or amides, which serve as the base for the amphoteric surfactant.
Amidation Reaction:
The coconut oil-derived fatty acids are reacted with amino acids such as glycine or diacetic acid derivatives to form an amide intermediate.
This reaction helps in preparing the molecule for amphoteric surfactant properties.
Quaternization & Neutralization:
The amide intermediate undergoes a chemical reaction with sodium monochloroacetate, leading to the formation of a betainic structure.
Sodium hydroxide (NaOH) is then used to neutralize the reaction, forming the disodium salt of the final surfactant.
Purification & Filtration:
The crude product is filtered and purified to remove any unreacted substances, ensuring high purity and safety.
Water is often added to adjust the final concentration, making the ingredient suitable for formulation use.
Quality Control & Packaging:
The final product undergoes quality checks, including pH testing, viscosity measurement, and stability analysis.
Once approved, Cocoamphocarboxyglycinate oxide is packaged in bulk containers or drums and shipped to manufacturers for use in cosmetics, skincare, haircare, and cleaning products.
This process ensures that Cocoamphocarboxyglycinate oxide remains a mild, effective, and eco-friendly surfactant, widely used in sulfate-free and sensitive-skin formulations.
History of Cocoamphocarboxyglycinate Oxide:
Cocoamphocarboxyglycinate oxide has an evolving history rooted in the demand for gentler, more skin-friendly surfactants.
In the early 20th century, traditional soaps and early synthetic surfactants like sodium lauryl sulfate (SLS) dominated the market, but concerns about skin irritation led to the search for milder alternatives.
By the mid-20th century, researchers developed amphoteric surfactants, which balanced cleansing power with mildness, leading to the introduction of compounds like amphodiacetates.
In the 1970s and 1980s, Cocoamphocarboxyglycinate oxide emerged as a coconut-derived surfactant that provided effective yet gentle cleansing, making it ideal for baby shampoos, sensitive skin products, and sulfate-free formulations.
As the beauty and personal care industries shifted towards sulfate-free and eco-friendly alternatives in the 1990s and 2000s, this surfactant gained widespread use in shampoos, body washes, and facial cleansers.
With the growing emphasis on sustainability in the 2010s and beyond, Cocoamphocarboxyglycinate oxide has become a key ingredient in natural and dermatologist-recommended products due to its biodegradability and compatibility with sensitive skin.
Today, Cocoamphocarboxyglycinate oxide remains a preferred choice for gentle cleansing formulations, balancing effectiveness with environmental responsibility.
Handling and Storage of Cocoamphocarboxyglycinate Oxide:
Handling:
General Precautions:
Handle with care, ensuring appropriate protective equipment (e.g., gloves, goggles) is used.
Avoid contact with eyes and prolonged skin exposure, although Cocoamphocarboxyglycinate oxide is generally non-irritating.
Ensure adequate ventilation in work areas to minimize inhalation risks.
Keep containers tightly closed when not in use to avoid contamination or spills.
Workplace Hygiene:
Wash hands thoroughly after handling.
Avoid ingestion or inhalation of Cocoamphocarboxyglycinate oxide.
Do not eat, drink, or smoke in the workplace.
Storage:
Temperature:
Store in a cool, dry place at temperatures between 5°C and 40°C (41°F to 104°F).
Container:
Store in sealed, appropriately labeled containers to prevent contamination.
Separation:
Keep away from incompatible substances, such as strong acids or oxidizing agents.
Avoid direct sunlight exposure to prevent degradation over time.
Stability and Reactivity of Cocoamphocarboxyglycinate Oxide:
Stability:
Chemical Stability:
Stable under normal conditions of use and storage.
Stable in aqueous solutions with a pH range of 8.5–10.5.
Decomposition Products:
May produce carbon dioxide (CO₂) and carbon monoxide (CO) when exposed to high temperatures or fires.
Conditions to Avoid:
Extreme heat, open flames, or direct sunlight.
Contact with strong acids, bases, or oxidizing agents may cause degradation or other unwanted reactions.
Reactivity:
Incompatibility:
Avoid contact with strong acids, strong oxidizers, and alkali metals to prevent any exothermic reactions or formation of dangerous products.
Reacts with strong acids to form neutralized compounds that may compromise the integrity of the formulation.
First Aid Measures of Cocoamphocarboxyglycinate Oxide:
Inhalation:
Move the person to fresh air immediately.
If symptoms persist (e.g., coughing, difficulty breathing), seek medical attention.
Skin Contact:
Rinse skin with plenty of water.
Remove contaminated clothing and wash before reusing.
If irritation develops, seek medical attention.
Eye Contact:
Rinse eyes immediately with plenty of water for 15–20 minutes, lifting the eyelids occasionally.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth thoroughly with water.
Do not induce vomiting unless directed by medical personnel.
If large quantities are ingested, seek medical attention immediately.
Fire Fighting Measures of Cocoamphocarboxyglycinate Oxide:
Suitable Extinguishing Media:
Water fog, foam, dry chemical, or carbon dioxide (CO₂) are suitable for extinguishing fires.
Use fire-fighting measures appropriate to the surrounding materials in the event of a fire.
Specific Hazards in Case of Fire:
Decomposition Products:
In the event of a fire, carbon dioxide (CO₂), carbon monoxide (CO), and other toxic gases may be released.
Wear self-contained breathing apparatus (SCBA) to avoid inhaling fumes.
Protective Equipment:
Firefighters should wear full protective gear, including self-contained breathing apparatus (SCBA), to avoid exposure to hazardous gases.
Accidental Release Measures of Cocoamphocarboxyglycinate Oxide:
Personal Precautions:
Avoid Direct Contact:
Wear appropriate personal protective equipment (PPE), including gloves and goggles, to prevent exposure.
Ensure proper ventilation in the affected area to minimize inhalation exposure.
Spill Cleanup:
Containment:
Prevent the spill from spreading by containing it with absorbent materials like sand or diatomaceous earth.
Cleanup:
Use water to dilute the spill, then collect the material using appropriate absorbent materials (e.g., paper towels or cloths).
Dispose of the spilled material according to local regulations.
Environmental Precautions:
Prevent Cocoamphocarboxyglycinate oxide from entering drains, sewers, or watercourses.
If contamination occurs, inform local authorities.
Exposure Controls/Personal Protective Equipment of Cocoamphocarboxyglycinate Oxide:
Occupational Exposure Limits:
There are no specific exposure limits set for Cocoamphocarboxyglycinate oxide.
However, general recommendations for mild surfactants should be followed.
Engineering Controls:
Ensure adequate ventilation in work areas to minimize inhalation exposure.
Use closed systems or local exhaust ventilation when handling large amounts of the substance in industrial settings.
Personal Protective Equipment (PPE):
Respiratory Protection:
Not typically required under normal conditions.
However, use a respirator if airborne concentrations exceed recommended limits.
Hand Protection:
Use protective gloves (e.g., nitrile gloves) to avoid prolonged skin contact.
Eye Protection:
Wear safety goggles or face shields if there is a risk of splashing or direct eye contact.
Skin Protection:
Wear protective clothing to avoid prolonged skin exposure.
Identifiers of Cocoamphocarboxyglycinate Oxide:
CAS Number: 68650-39-5
INCI Name: Cocoamphocarboxyglycinate oxide
Chemical Formula: C20H38N2Na2O6
EINECS/EC Number: 272-125-9
Molecular Weight: Approximately 460-500 g/mol
Appearance: Clear to pale yellow liquid
Solubility: Water-soluble
pH Range: Approximately 8.5–10.5 (in a 10% aqueous solution)
Synonyms: Cocoamphodiacetate, Disodium Cocoamphodipropionate, Amphoteric surfactant
IUPAC Name: Disodium N-(2-carboxyethyl)-N-(coconut oil alkyl)aminodiacetate
Other Trade Names: Miranol® C2M, Ampholac® 7C, Mackam® 2C, Rewoteric® AM C
HS Code: 3402.90
UNII (FDA Code): 01F2DPE4AO
CAS Number: 68650-39-5
ECHA InfoCard: 100.065.474
EC Number: 272-043-5
UNII: 18L9G3U51M
CompTox Dashboard (EPA): DTXSID9029483
Properties of Cocoamphocarboxyglycinate Oxide:
Appearance: Clear to pale yellow liquid
Odor: Mild or nearly odorless
Solubility: Fully soluble in water
Viscosity: Low to moderate
Density: 1.05–1.10 g/cm³
pH Range: 8.5–10.5
Boiling Point: > 100°C
Flash Point: Non-flammable under normal conditions
Boiling Point: 100°C
Melting Point: -12°C
pH: 8.0
Solubility: Soluble in water
Form: Liquid
Physical state: Liquid
Color: Yellow
Odor: Characteristic
Odor Threshold: No data available
pH (As Is): 8
Melting point/range: No data available
Boiling point/boiling range: >100°C
Flash Point: No data available
Flammability: No data available
Auto-ignition temperature: No data available
Water solubility: Soluble
Solubility in other solvents No data available
Partition coefficient (n-Octanol/water): No data available
Vapor Density: > 1
Evaporation rate: > 1
Vapor Pressure (25°C): ~20 mm
Specific Gravity (25°C): 1.17
Specifications of Cocoamphocarboxyglycinate Oxide:
Appearance: Clear to pale yellow liquid
Color (Gardner):≤ 5
Odor:Mild or nearly odorless
Viscosity (Brookfield, 25°C):50–1000 cP
Density (25°C):1.05–1.10 g/cm³
Active Content (by weight):30–35%
pH (10% aqueous solution, 25°C):8.5–10.5
Water Content:≤ 5%
Free Alkali (as NaOH):≤ 0.5%
Solubility:Completely soluble in water
Names of Cocoamphocarboxyglycinate Oxide:
Regulatory process names:
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
IUPAC names:
3-(tridecyloxy)propanenitrile
3-tridecoxypropanenitrile
Disodium cocoamphodiacetate
Disodium cocoamphodiacetate
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
Imidazolium compounds, 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, inner salts, disodium salts
imidazolium compounds, 1-[2-(carboxymethoxy)ethyl}-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hidroxides,sodium salts
Other names:
DSCADA
Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide
Other identifier:
68650-39-5
