OCTOXYGLYCERIN
Octoxyglycerin is a versatile moisturizer and can enhance the antimicrobial performance of other ingredients to keep products intact.
Octoxyglycerin reliably inhibits the growth and multiplication of odour-causing bacteria, while at the same time not affecting the beneficial skin flora.
Octoxyglycerin is a multifunctional cosmetic ingredient used as an active ingredient in deodorants and as an emollient and moisturizer in skin care.
CAS Number: 70445-33-9
EC Number: 274-273-0
Molecular Formula: C8H18O3
Molecular Weight: 174.23 g/mol
Synonyms: 70445-33-9, Ethylhexylglycerin, 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol, Octoxyglycerin, 3-(2-ethylhexoxy)propane-1,2-diol, 3-(2-ethylhexyloxy)propane-1,2-diol, 3-((2-Ethylhexyl)oxy)propane-1,2-diol, 3-(2-ethylhexyloxy)-1,2-propanediol, UNII-147D247K3P, 147D247K3P, 3-[(2-ethylhexyl)oxy]propane-1,2-diol, 1,2-Propanediol, 3-((2-ethylhexyl)oxy)-, EC 408-080-2, MFCD03790878, ETHYLHEXYLGLYCERIN (MART.), ETHYLHEXYLGLYCERIN [MART.], Glycerol alpha-(2-Ethylhexyl) Ether, 3-[(2-Ethylhexyl)oxy]-1,2-propanediol, ethyl hexyl glycerine, LADY GOONG, SCHEMBL99276, DTXSID80990652, ETHYLHEXYLGLYCERIN [WHO-DD], 2-ethyl-1-hexyl monoglyceryl ether, BCP30328, C11H24O3, AKOS030240472, DB14557, AS-63022, SY055478, CS-0152371, E1044, NS00001816, D71207, A836886, Q5404486, Ethylhexyl Glycerin;Octoxyglycerin;3-(2-Ethylhexyloxy)propane-1,2-diol, 1,2-Propanediol,3-(2-ethylhexyl)oxy;2-propanediol,3-[(2-ethylhexyl)oxy]-1, Lexgard E;3-[2-(EthyL; OCTOXYGLYCERIN; ETHYLHEXYLGLYCERIN; Ethylhexyl Glecerine; Ethyl hexyl glycerol; Glycerol α-(2-Ethylhexyl) Ether; 1,2-Propanediol, 3-[(2-ethylhexyl)oxy]; 147D247K3P; 3-(2-ethylhexyloxy)propane-1,2-diol; 3-[(2-Ethylhexyl)oxy]-1,2-propandiol ; 3-[(2-Ethylhexyl)oxy]-1,2-propanediol; 3-[(2-Éthylhexyl)oxy]-1,2-propanediol; 3-[(2-ethylhexyl)oxy]propane-1,2-diol; 70445-33-9; UNII:147D247K3P; [70445-33-9]; 3-((2-Ethylhexyl)oxy)propane-1,2-diol; 3-(2-ethylhexoxy)propane-1,2-diol; 3-(2-ethylhexyloxy)-1,2-propanediol; 3-[2-(ethyl hexyl)oxyl]-1,2-propandiol; 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol; MFCD03790878; 70445-33-9; Ethylhexylglycerin
Octoxyglycerin is a glyceryl ether that is commonly used in cosmetic formulations as part of a preservative system.
Octoxyglycerin is a colorless, transparent liquid, and is valued for its versatile properties.
Notably, Octoxyglycerin is recognized for its antibacterial and deodorizing effects, making it an effective solution in maintaining hygiene within cosmetic products.
Beyond Octoxyglycerin's antibacterial capabilities, it also has the ability to enhance the effect of alcohol-based ingredients and can increase the moisturizing properties of products, which makes it a multifunctional moisturizer and skin conditioner.
This makes Octoxyglycerin an important ingredient in improving the performance and quality of cosmetic formulations.
Octoxyglycerin is a bacteriostatic agent, meaning it can help inhibit the growth of microorganisms, which is critical in preventing product degradation and maintaining safety.
Octoxyglycerin can be added to both the aqueous phase and the oil phase of cosmetic products, depending on the desired formulation.
When added to the water phase, Octoxyglycerin works to create an antibacterial protective effect that benefits the entire formula, ensuring that the product remains free from bacterial contamination.
Octoxyglycerin's bacteriostatic action also reduces the need for additional preservatives, such as Nipagin ester products, which can be potentially harsh and irritating to the skin.
This property makes Octoxyglycerin a desirable ingredient for those looking to create more natural and preservative-light cosmetic products.
Furthermore, Octoxyglycerin is an excellent softener, moisturizing agent, and wetting agent, making it ideal for inclusion in various skin care emulsion systems.
Octoxyglycerin is often used in products such as shampoos, shower gels, and other formulations that rely on surfactants.
The ability of Octoxyglycerin to prevent the growth of microorganisms is particularly beneficial in personal care items, where it helps to maintain product integrity and effectiveness.
In skin care formulations, Octoxyglycerin can address issues such as cream absorption, stickiness, and whitening skin imperfections, leading to smoother and more comfortable application experiences.
Octoxyglycerin also has deodorizing properties, which is another key benefit.
Octoxyglycerin helps prevent the growth and reproduction of bacteria that cause unpleasant odors, without disrupting the beneficial skin flora that protects the skin.
This allows Octoxyglycerin to effectively control and prevent odors in personal care products, maintaining a fresh and clean feel for the user.
Octoxyglycerin's deodorizing effect, while gentle, ensures that it does not negatively impact the skin’s natural ecosystem.
One of the advantages of Octoxyglycerin is its ability to increase the effectiveness of conventional cosmetic preservatives such as ethanol, phenoxyethanol, methylisothiazolinone, and methylparaben.
When Octoxyglycerin is added to a formula, it enhances the performance of these preservatives, which allows for a reduction in the overall quantity of these substances.
This helps in creating safer, more consumer-friendly products, with lower amounts of potentially irritating or harmful preservatives.
In terms of formulation, Octoxyglycerin should ideally be applied first to the emulsification system, ensuring that it is dispersed evenly into the aqueous phase.
The use of mild polybasic alcohol can aid in improving the dispersion of Octoxyglycerin in the aqueous phase, ensuring that it is more evenly distributed for maximum effectiveness.
Additionally, when used in combination with phenoxyethanol, Octoxyglycerin can be dissolved in the oil phase for more optimal results, making it highly adaptable to various formulations.
Octoxyglycerin is also known for being a safe alternative to parabens, which are commonly used as preservatives in cosmetics but have raised concerns due to their potential for skin irritation.
Octoxyglycerin, on the other hand, is generally considered non-irritating and safe for use, making it an appealing choice for formulators seeking safer alternatives.
However, it should be noted that in rare cases, Octoxyglycerin can still be an irritant to the skin, so careful formulation and testing are advised.
In addition to all these benefits, Octoxyglycerin is used to maintain the consistency of products like shampoos, where it helps to stabilize the formulation and prevent changes in texture or appearance over time.
Octoxyglycerin's multifunctional nature makes it a valuable ingredient for enhancing the quality and performance of a wide variety of cosmetic and personal care products.
Octoxyglycerin is a globally approved, versatile, and multifunctional additive that serves as a very effective deodorizing agent, emollient, and antimicrobial stabilizer.
Octoxyglycerin's ability to improve the skin feel of cosmetic formulations and enhance the performance of other ingredients is highly prized by formulators.
By reliably inhibiting the growth and multiplication of odor-causing bacteria, while not negatively impacting the beneficial skin flora, Octoxyglycerin helps maintain both the hygiene and the natural balance of the skin.
Additionally, Octoxyglycerin enhances the efficacy of traditional preservatives, enabling the formulation of more effective, consumer-safe, and longer-lasting cosmetic products.
This makes Octoxyglycerin an indispensable ingredient in modern skincare and personal care formulations.
Octoxyglycerin is a natural preservative and skin conditioning agent made from glycerin.
Octoxyglycerin is derived from synthetic raw materials.
Octoxyglycerin has multiple benefits including acting as mild humectant, an emollient and can improve the skin feel of cosmetic formulations.
Octoxyglycerin is a multifunctional cosmetic ingredient used as an active component in deodorants, as an emollient and humectant in skin care, and boosting the anti-microbial performance of other ingredients to protect products from spoilage.
Octoxyglycerin is used in foundation, lipstick, moisturizers, make up, shampoo, conditioner, deodorant, antiperspirant, exfoliant, lotions, baby shampoo/lotion/soap, shaving cream, fragrance, makeup remover, tanning lotion, sunscreen.
Octoxyglycerin is a glyceryl ether that is commonly used as part of a preservative system in cosmetic preparations.
Octoxyglycerin is a relatively new cosmetic ingredient that is used for its surfactant, emollient, skin-conditioning and antimicrobial properties.
Octoxyglycerin is an alkyl glyceryl ether.
This means that the ethylhexyl group is bound to glycerin at one end by an ether linkage.
Despite the different types of names for these ingredients, they all consist of an alkyl group bound to glycerin by an ether linkage.
Octoxyglycerin and the other alkyl glyceryl ether ingredients may be used in bath products.
Octoxyglycerin may be used in body and hand products.
Octoxyglycerin may be used in cleansing products.
Octoxyglycerin is used in deodorants, eye makeup, foundations, hair care products and suntan products.
Octoxyglycerin is a colorless liquid.
As cosmetic system of no added preservatives, Octoxyglycerin has bacteriostasis, moisturizing effect.
Due to a synergistic effect of Octoxyglycerin, dosage of traditional preservatives in cosmetics are reduced, and the antibacterial effect of multi-functional cosmetic additives such as glycol and fatty acids are improved, and unpleasant odor caused by sebum is suppressed.
Octoxyglycerin is a clear liquid preservative derived from vegetable glycerin, often coconut or palm oil.
Octoxyglycerin has three jobs in our products: prevent the product from spoiling, keep the product from separating, and soften your skin.
Octoxyglycerin does this by breaking the surface tension in liquids allowing them to mix together and “soak in” better.
The emollient aspect of the ingredients vegetable glycerin source also makes our products feel creamier and softer on skin, and Octoxyglycerin’s antimicrobial qualities help fight germs and bacteria.
Octoxyglycerin is a fantastic multitasker. For one thing, Octoxyglycerin is a much safer substitute for parabens, which are very controversial.
Octoxyglycerin also helps keep bacteria and germs off your skin and from forming inside the bottle, which in turn prevents body odor and other unfavorable scents from proliferating.
Octoxyglycerin also keeps our products perfectly blended and has an added bonus of making your skin feel soft and smooth.
Octoxyglycerin is rarely an allergen.
Uses of Octoxyglycerin:
Octoxyglycerin is a multifunctional ingredient commonly used in cosmetic and personal care products.
Octoxyglycerin's primary uses include:
Preservative:
Octoxyglycerin acts as a mild preservative, preventing the growth of bacteria and fungi in formulations, often used as a substitute or in combination with traditional preservatives.
Skin Conditioning:
Octoxyglycerin has emollient properties, which help to hydrate and soften the skin.
Antimicrobial:
Octoxyglycerin offers antimicrobial properties, which can help protect products from contamination and contribute to skin health.
Fragrance Enhancer:
Octoxyglycerin is used to boost the effectiveness of fragrances in cosmetics and toiletries.
Moisturizing:
Octoxyglycerin helps retain moisture in the skin, making it an ideal ingredient in moisturizing creams, lotions, and serums.
Emulsifier:
Octoxyglycerin helps stabilize emulsions (mixtures of oil and water), ensuring the even distribution of ingredients in formulations like creams and lotions.
Improves Product Texture:
Octoxyglycerin can enhance the texture of products, providing a smooth, non-greasy feel on the skin.
Haircare Benefits:
In haircare products, Octoxyglycerin helps improve hair texture and manageability while providing conditioning benefits.
Anti-inflammatory:
Some studies suggest that Octoxyglycerin may have mild anti-inflammatory effects, benefiting sensitive or irritated skin.
Solvent:
Octoxyglycerin can also act as a solvent, helping other active ingredients dissolve or disperse more effectively in the formulation.
Applications of Octoxyglycerin:
Octoxyglycerin is a versatile ingredient widely used in the cosmetic and personal care industry due to its multifunctional properties.
As a mild preservative, Octoxyglycerin helps extend the shelf life of products by preventing the growth of bacteria, fungi, and other microorganisms, making it a popular alternative or complement to harsher preservatives.
Octoxyglycerin's skin-conditioning and emollient qualities allow it to hydrate and soften the skin, contributing to smooth, moisturized skin with a non-greasy feel.
In addition to Octoxyglycerin's antimicrobial properties, it enhances the effectiveness of fragrances, ensuring they last longer in products such as lotions, deodorants, and perfumes.
Octoxyglycerin also acts as an emulsifier, stabilizing the mixture of oil and water in creams and lotions, improving their texture and spreadability.
Octoxyglycerin is commonly found in haircare products as well, where it enhances hair texture, manageability, and shine.
Additionally, Octoxyglycerin's mild anti-inflammatory properties make it suitable for sensitive or irritated skin, adding to its appeal in skincare formulations.
With its broad range of applications, Octoxyglycerin continues to be a key ingredient in clean beauty, anti-aging, and everyday skincare products.
Benefits of Octoxyglycerin:
Octoxyglycerin offers several benefits for both skin and product formulation:
Gentle Preservation:
Octoxyglycerin provides effective preservation without the harshness of traditional preservatives, reducing the risk of irritation, particularly for sensitive skin.
Moisturizing:
Octoxyglycerin's emollient properties help keep the skin hydrated, soft, and smooth, enhancing the overall skin texture and appearance.
Antimicrobial Protection:
By preventing microbial growth, Octoxyglycerin protects products from contamination and ensures safer, longer-lasting products.
Enhanced Skin Comfort:
Octoxyglycerin helps soothe and condition the skin, making it ideal for sensitive or irritated skin, contributing to a calming effect.
Improved Product Performance:
Octoxyglycerin boosts the effectiveness of other ingredients, including fragrances, making scents last longer and enhancing the overall performance of formulations.
Stabilizes Formulations:
Octoxyglycerin helps maintain the stability of emulsions, improving the texture, spreadability, and consistency of creams and lotions.
Non-Greasy Feel:
Octoxyglycerin adds a silky, smooth texture to products without leaving a greasy residue, ensuring a pleasant user experience.
Anti-Inflammatory:
Mild anti-inflammatory properties can benefit individuals with redness or inflammation, adding extra care for sensitive skin.
Haircare Benefits:
In hair products, Octoxyglycerin contributes to smoother, shinier, and more manageable hair, providing conditioning benefits.
Production of Octoxyglycerin:
Octoxyglycerin is produced through a chemical process known as esterification, where glycerin (glycerol) reacts with 2-ethylhexanol in the presence of a catalyst, usually an acid catalyst, under controlled temperature and pressure conditions.
During this reaction, the hydroxyl group (-OH) of the glycerin molecule bonds with the hydroxyl group of 2-ethylhexanol, forming an ester bond and producing Octoxyglycerin.
The reaction is carefully monitored to ensure high purity and yield, and the final product is typically purified through distillation or other refining processes to remove any residual by-products or unreacted starting materials.
Synthesis of Octoxyglycerin:
The synthesis of Octoxyglycerin begins with the esterification of glycerin, a compound commonly derived from plant oils or animal fats, with 2-ethylhexanol, a branched-chain alcohol that is itself typically synthesized from petroleum-based feedstocks.
The esterification reaction is carried out under anhydrous conditions, often requiring elevated temperatures and the addition of a strong acid, such as sulfuric acid, to catalyze the reaction.
Once the esterification is complete, the mixture undergoes separation and purification steps, including neutralization, distillation, and filtration, to isolate pure Octoxyglycerin.
This process ensures the resulting compound meets the high standards required for use in personal care products, where purity and safety are critical.
Occurrence of Octoxyglycerin:
Octoxyglycerin is not commonly found in nature in its pure form, as it is a synthetic compound.
However, Octoxyglycerin's precursor components, glycerin and 2-ethylhexanol, can be derived from natural sources.
Glycerin is often obtained through the hydrolysis of fats and oils, both animal and plant-based, while 2-ethylhexanol is typically synthesized from petrochemical sources.
Though Octoxyglycerin itself does not naturally occur in large quantities in plants or animals, the compound is synthesized and widely used in cosmetics, personal care products, and pharmaceuticals due to its beneficial properties, such as its ability to act as a mild preservative, emulsifier, and skin conditioning agent.
Handling and Storage of Octoxyglycerin:
Handling:
When handling Octoxyglycerin, ensure good ventilation in the work environment to avoid inhalation of vapors.
Avoid direct contact with skin and eyes.
Wear appropriate protective equipment such as gloves and safety glasses.
Handle Octoxyglycerin with care to prevent spills or accidental release.
Storage:
Store Octoxyglycerin in a cool, dry place, away from direct sunlight and sources of heat or ignition.
Keep containers tightly closed and store them in a well-ventilated area.
Avoid exposure to incompatible materials such as strong oxidizers.
Stability and Reactivity of Octoxyglycerin:
Stability:
Octoxyglycerin is generally stable under normal conditions of use and storage.
Octoxyglycerin should be kept away from extreme temperatures and sources of ignition to maintain its stability.
Reactivity:
Octoxyglycerin is not highly reactive but should be kept away from strong acids, bases, and oxidizing agents.
Octoxyglycerin does not undergo significant decomposition under typical storage conditions, but exposure to elevated temperatures or incompatible materials may lead to hazardous decomposition products.
First Aid Measures of Octoxyglycerin:
Inhalation:
If inhaled, remove the person from the area to fresh air immediately.
If symptoms such as coughing or difficulty breathing occur, seek medical attention.
Skin Contact:
In case of skin contact, wash the affected area with soap and water.
If irritation persists or if there is a significant reaction, seek medical advice.
Eye Contact:
If Octoxyglycerin comes into contact with the eyes, rinse immediately with plenty of water for at least 15 minutes.
Seek medical attention if irritation persists.
Ingestion:
If ingested, do not induce vomiting.
Rinse the mouth with water and seek medical attention immediately.
Do not give anything by mouth if the person is unconscious or convulsing.
Firefighting Measures of Octoxyglycerin:
Extinguishing Media:
Use water spray, foam, dry chemical, or carbon dioxide (CO2) to extinguish a fire involving Octoxyglycerin.
Choose the extinguishing media based on the materials involved in the fire.
Special Firefighting Procedures:
Firefighters should wear self-contained breathing apparatus and full protective gear to prevent inhalation of harmful fumes.
Octoxyglycerin may emit hazardous fumes in case of a fire, so proper ventilation and protective measures are essential.
Hazardous Combustion Products:
During a fire, Octoxyglycerin may decompose to release carbon monoxide, carbon dioxide, and other toxic gases.
These fumes can be hazardous to health, so appropriate safety precautions should be followed.
Accidental Release Measures of Octoxyglycerin:
Personal Precautions:
Wear appropriate protective equipment, including gloves, safety glasses, and respiratory protection if necessary.
Ensure adequate ventilation to avoid inhalation of vapors.
Environmental Precautions:
Prevent Octoxyglycerin from entering drains, sewers, or water systems.
Octoxyglycerin is not expected to be highly toxic to aquatic life, but spills should be contained and cleaned up to prevent environmental contamination.
Cleanup Methods:
Absorb the spilled material using inert absorbent materials like sand, earth, or vermiculite.
Collect the material into an appropriate container for disposal according to local regulations.
Clean the area thoroughly after the spill has been removed.
Exposure Controls/Personal Protective Measures of Octoxyglycerin:
Exposure Limits:
There are no specific exposure limits for Octoxyglycerin established by regulatory bodies.
However, general workplace safety guidelines should be followed to minimize exposure.
Engineering Controls:
Ensure good ventilation in areas where Octoxyglycerin is used or stored to prevent the buildup of vapors.
Personal Protective Equipment (PPE):
Eyes:
Wear safety glasses or goggles to protect against accidental splashes.
Skin:
Wear suitable gloves and protective clothing to prevent skin contact, particularly in cases of prolonged exposure.
Respiratory:
In situations where vapors or dust may be inhaled, use an appropriate respirator or dust mask.
Ensure the mask is suitable for the exposure levels.
Identifiers of Octoxyglycerin:
Chemical Name: 2-Ethylhexyl Glycerol
Common Name: Octoxyglycerin
CAS Number: 70445-33-9
EC Number: 274-273-0
Molecular Formula: C8H18O3
Molecular Weight: 174.23 g/mol
IUPAC Name: 2-ethylhexyl 2-hydroxypropyl ether
Synonyms: 2-Ethylhexyl glycerol, 2-Ethylhexanol glycerol ether, 2-Ethylhexylglyceryl ether
SMILES (Simplified Molecular Input Line Entry System): CCCCC(C)OCC(CO)O
InChI (International Chemical Identifier): InChI=1S/C8H18O3/c1-3-5-7(2)9-6-8(4)10/h7-8,9-10H,3-6H2,1-2H3
InChI Key: VZLFZWVYHBJGHY-UHFFFAOYSA-N
UNII (Unique Ingredient Identifier): L0R2B72Z7O
Properties of Octoxyglycerin:
Appearance: Clear, colorless to pale yellow liquid.
Solubility: Soluble in oils and alcohols, slightly soluble in water.
Boiling Point: Approximately 238°C (460°F).
Melting Point: Around -50°C (-58°F).
Density: Approximately 0.94 g/cm³ at 20°C.
Viscosity: Moderate, contributing to a smooth texture in formulations.
pH: Neutral, around 7, making it compatible with most products.
Odor: Mild, slightly sweet scent.
Molecular Weight: 204.31 g/mol
XLogP3-AA: 1.9
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 9
Exact Mass: 204.17254462 Da
Monoisotopic Mass: 204.17254462 Da
Topological Polar Surface Area: 49.7Ų
Heavy Atom Count: 14
Complexity: 117
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Specifications of Octoxyglycerin:
Appearance: Clear, colorless to pale yellow liquid
Assay (Purity): ≥ 99% (by GC or HPLC)
pH (1% solution in water): 5.0 - 7.0
Refractive Index (20°C): 1.438 - 1.440
Density (20°C): 0.94 - 0.96 g/cm³
Boiling Point: ≥ 238°C (460°F)
Flash Point: ≥ 150°C (302°F)
Viscosity (at 25°C): 30 - 50 cP
Water Content: ≤ 0.5%
Odor: Mild, slightly sweet
Heavy Metals (as Pb): ≤ 10 ppm
Arsenic: ≤ 2 ppm
Microbial Limits: Total aerobic microbial count ≤ 100 cfu/g, Yeast & mold ≤ 10 cfu/g
Alternative Products of Octoxyglycerin:
Caprylyl Glycol
Hexylene Glycol
Pentylene Glycol
Glycerin
Propylene Glycol
Butylene Glycol
