DECAMETHYLCYCLOPENTASILOXANE
Decamethylcyclopentasiloxane, a volatile and colorless organosilicon compound, is widely used in personal care products for its ability to provide a silky, non-greasy feel and to act as a carrier for other ingredients.
Known for its rapid evaporation and water-repellent properties, decamethylcyclopentasiloxane is also employed in industrial applications like dry cleaning and as a component in silicone-based materials.
While valued for its versatility, Decamethylcyclopentasiloxane has faced regulatory scrutiny over potential environmental and health concerns, leading to restrictions on its use in certain regions.
CAS Number: 541-02-6
EC Number: 208-764-9
Molecular Formula: C10H30O5Si5
Molar Mass: 370.77 g/mol
Synonyms: Cyclopentamethicone, Cyclic dimethylsiloxane pentamer, D5, D5, 2,2,4,4,6,6,8,8,10,10-Decamethylcyclopentasiloxane, DECAMETHYLCYCLOPENTASILOXANE, 541-02-6, Cyclopentasiloxane, decamethyl-, Cyclomethicone 5, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, Dimethylsiloxane pentamer, Dekamethylcyklopentasiloxan, CYCLOMETHICONE, UNII-0THT5PCI0R, 0THT5PCI0R, Ddecamethylcyclopentasiloxane, Dow corning 345 fluid, Dow corning 345, NUC silicone VS 7158, Silicon SF 1202, Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-, Cyclic dimethylsiloxane pentamer, MFCD00046966, Union carbide 7158 silicone fluid, KF 995, VS 7158, D5-sil, CCRIS 1328, HSDB 5683, Dekamethylcyklopentasiloxan [Czech], EINECS 208-764-9, decamethyl cyclopentasiloxane, SF 1202, BRN 1800166, Ciclopentasiloxane, Cyclomethicone D5, D5 Cyclomethicone, dimethylcyclopentasiloxane, Decamethylcylopentasiloxane, DSSTox_CID_7184, EC 208-764-9, DSSTox_RID_78338, DSSTox_GSID_27184, SCHEMBL28497, N-Propylheptamethyltrisiloxane, 4-04-00-04128 (Beilstein Handbook Reference), CHEMBL1885178, DTXSID1027184, CHEBI:191092, Decamethylcyclopentasiloxane, 97%, BCP15826, Tox21_303170, CD3770, AKOS008901199, ZINC169743678, CS-W009767, DB11244, 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane, NCGC00163981-01, NCGC00257224-01, AS-59731, CAS-541-02-6, D1890, D3770, Decamethylcyclopentasiloxane (cyclic monomer), FT-0665531, D78203, S05475, Decamethylcyclopentasiloxane, analytical standard, Q414350, decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, UNII-NMQ347994Z component XMSXQFUHVRWGNA-UHFFFAOYSA-N, Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #, D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material, 0THT5PCI0R, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecan [German] [ACD/IUPAC Name], 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane [ACD/IUPAC Name], 2,2,4,4,6,6,8,8,10,10-Décaméthyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilécane [French] [ACD/IUPAC Name], 208-764-9 [EINECS], 541-02-6 [RN], Cyclic dimethylsiloxane pentamer, cyclomethicone 5, Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl- [ACD/Index Name], D5 Cyclomethicone, decamethyl cyclopentasiloxane, Decamethylcyclopentasiloxane [Wiki], Decamethyl-cyclopentasiloxane, Dekamethylcyklopentasiloxan [Czech], GY5945200, MFCD00046966 [MDL number], 1,3,5,7,9,2λ2,4λ2,6λ2,8λ2,10λ2-pentaoxapentasilecane, 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane; D5, 4-04-00-04128 [Beilstein], 4-04-00-04128 (Beilstein Handbook Reference) [Beilstein], CYCLOMETHICONE, Cyclopentasiloxane [ACD/Index Name], cyclopentasiloxane, decamethyl-, D5, Ddecamethylcyclopentasiloxane, decamethy lcyclopentasiloxane, decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane, decamethylcyclopentasiloxane, ???, Dekamethylcyklopentasiloxan [Czech], Dimethylsiloxane pentamer, Dow corning 345 [Trade name], Dow corning 345 fluid [Trade name], EINECS 208-764-9, NCGC00163981-01, NUC silicone VS 7158 [Trade name], Silicon SF 1202 [Trade name], UNII:0THT5PCI0R, UNII-0THT5PCI0R, Union carbide 7158 silicone fluid [Trade name]
Decamethylcyclopentasiloxane leaves skin feeling soft, silky, without leaving any oily residue or build-up.
Decamethylcyclopentasiloxane is oil-free, removes stickiness and spreads evenly.
Decamethylcyclopentasiloxane is one of the most abundant compounds measured in urban indoor and outdoor air.
Decamethylcyclopentasiloxane is used in many personal care products.
Additionally, particulate matter from urban areas is richer in silicon than less populated areas.
The vast majority of decamethylcyclopentasiloxane escapes into the atmosphere and the main loss source of decamethylcyclopentasiloxane is the hydroxyl radical.
Experimentally and computationally simulated environmental data from the room.
Decamethylcyclopentasiloxane and OH experiments provide insight into aerosol efficiency and chemistry.
Aerosol yields and composition are shown as a function of NOx concentration.
Decamethylcyclopentasiloxane is derived from Silicon, Oxygen and alkane.
They are used because of their special chemical properties: they are odorless, colorless, oil-free, easy to apply and dries quickly.
This family covers multiple categories of substances: Cyclotetrasiloxanes (D4), Cyclopentasiloxanes (D5), and Cyclohexasiloxanes (D6).
The term "silicone" may also be used to refer to siloxanes.
Decamethylcyclopentasiloxane is an organosilicon compound with the formula [(CH3)2SiO]5.
Decamethylcyclopentasiloxane is a slightly volatile, colorless and odorless liquid.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
Decamethylcyclopentasiloxane are cyclic in structure with an interconnected monomer backbone of one silicon and two oxygen atoms.
Decamethylcyclopentasiloxane is used as a skin emollient in cosmetics and personal products.
Decamethylcyclopentasiloxane, also known as cyclopentasiloxane, decamethyl, is an industrial chemical.
Decamethylcyclopentasiloxane is a volatile polydimethyl cyclosiloxane mainly composed of decamethyl cyclopentasiloxane.
Decamethylcyclopentasiloxane is clear, odorless, basically odorless, oil-free.
Decamethylcyclopentasiloxane is an organosilicon compound with the formula [(CH3)2SiO]5.
Decamethylcyclopentasiloxane is a slightly volatile, colorless and odorless liquid.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
In personal care products, Decamethylcyclopentasiloxane acts as a "carrier", allowing the products to spread smoothly and easily, Provides a silky, luxurious feel during application.
In dry cleaning, Decamethylcyclopentasiloxane transfers detergent to clothes and rinses away accumulated dirt and oil.
Decamethylcyclopentasiloxane is also among the most studied materials for consumer and industrial use.
Decamethylcyclopentasiloxane is known to evaporate and dry quickly.
Decamethylcyclopentasiloxanes are also known to repel water and slide easily.
Decamethylcyclopentasiloxane is a clear, colorless liquid with a relatively low boiling point and high vapor pressure.
This makes Decamethylcyclopentasiloxane volatile at room temperature, causing it to evaporate readily into the air.
Decamethylcyclopentasiloxanes volatility contributes to its use as a carrier for other ingredients in personal care and cosmetic formulations.
Decamethylcyclopentasiloxane and octamethylcyclotetrasiloxane (D4) are part of a larger class of compounds known as siloxanes.
Decamethylcyclopentasiloxane are characterized by their alternating silicon and oxygen atoms, often bonded to organic groups like methyl (CH3) groups.
Decamethylcyclopentasiloxane have a wide range of applications due to their unique properties, including thermal stability, electrical insulating properties, and compatibility with various materials.
Decamethylcyclopentasiloxane is commonly used in cosmetic and personal care products for its beneficial properties.
Decamethylcyclopentasiloxane imparts a smooth and soft feel to the skin and hair.
Decamethylcyclopentasiloxane helps products spread easily and evenly.
Decamethylcyclopentasiloxane ability to evaporate quickly gives a non-greasy finish to products.
Decamethylcyclopentasiloxane serves as a carrier for other ingredients in formulations.
Decamethylcyclopentasiloxane has been subject to regulatory scrutiny due to concerns about its potential environmental impact and health effects.
Regulatory agencies in various regions have evaluated Decamethylcyclopentasiloxane's safety, and restrictions or limitations on its use in certain product categories, especially in personal care products, have been implemented in some cases.
Decamethylcyclopentasiloxanes are also known to form a protective barrier on the skin and hair.
This can help detangle your hair, prevent breakage, and reduce frizz.
Decamethylcyclopentasiloxane sometimes appears on the label as D5.
Decamethylcyclopentasiloxane can also be placed under the broader category name of cyclomethicone.
Decamethylcyclopentasiloxane is different from another siloxane known as dimethicone or polydimethylsiloxane (PDMS).
Decamethylcyclopentasiloxane is a general term describing a single individual and/or a mixture of cyclic siloxane materials.
Decamethylcyclopentasiloxane has many uses and is found in a variety of consumer products.
These materials are obtained from the natural elements silicon and oxygen.
Decamethylcyclopentasiloxane creates many of the positive qualities we associate with personal care products: lush texture, silky smoothness, shine and is used in smooth applications.
Decamethylcyclopentasiloxane helps personal care products to be non-flammable and non-irritating.
Decamethylcyclopentasiloxane, for example, reduce the white residue and sticky feeling of antiperspirants and help "long-lasting" makeup maintain its strength.
Shampoos and conditioners with decamethylcyclopentasiloxane have better shine.
Decamethylcyclopentasiloxane provides wetting and spreading properties.
Decamethylcyclopentasiloxane any of various compounds containing alternating silicon and oxygen atoms.
Decamethylcyclopentasiloxane is usually a linear or cyclic arrangement in which one or two organic groups are attached to each silicon atom.
Decamethylcyclopentasiloxane is a volatile cyclosiloxane that is an essential ingredient for a wide variety of cosmetics and body care.
Decamethylcyclopentasiloxane is well compatible with most solvents.
Decamethylcyclopentasiloxane, a synthetic substance, consists of silicon and oxygen.
Sometimes elements such as hydrogen and carbon are also used.
Decamethylcyclopentasiloxane is an organosilicon compound with the formula [(CH3)2SiO]5.
Decamethylcyclopentasiloxane is a colorless and odorless liquid that is slightly volatile.
Decamethylcyclopentasiloxane is a fluid exhibiting low surface tension.
Decamethylcyclopentasiloxane has lubricating properties combined with volatility characteristics.
Decamethylcyclopentasiloxane imparts soft silky feel to the skin leaving no oil residue or build up.
Decamethylcyclopentasiloxane is non-greasy, detackifying and spreads evenly.
Decamethylcyclopentasiloxane is widely used in applications such as antiperspirants, deodorants, hair sprays, cleansing-, skin creams, lotions, bath oils, sun-tanning and shaving products, make-up and nail polishes.
Decamethylcyclopentasiloxane has a shelf life of 24 months.
Decamethylcyclopentasiloxane is used in personal care products including skin creams, cosmetics, shampoos, deodorants and conditioners.
Decamethylcyclopentasiloxane is also used in various applications such as industrial cleaning fluids and dry cleaning solvents.
Decamethylcyclopentasiloxane is an organosilicon compound with the formula [(CH3)2SiO]5.
Decamethylcyclopentasiloxane is a colorless and odorless liquid that is slightly volatile.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
Decamethylcyclopentasiloxane is commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Decamethylcyclopentasiloxane is widely used in cosmetic products due to its unique functions as antistatic, emollient, humectant, solvent, viscosity controlling and hair conditioning agent.
Decamethylcyclopentasiloxane is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
Decamethylcyclopentasiloxane is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Decamethylcyclopentasiloxane is a silicone fluid commonly used in cosmetics such as deodorants, sunblocks, hair sprays and skin care products to lubricate, waterproof and provide shine.
Like all other silicones, Decamethylcyclopentasiloxane has a unique fluidity that makes it easily spreadable.
When applied to the skin and hair, Decamethylcyclopentasiloxane gives a silky and soft feeling to the touch and acts as a mild water repellent by forming a protective barrier on the skin.
Decamethylcyclopentasiloxane is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Decamethylcyclopentasiloxane is used in personal care products including skin creams, cosmetics, shampoos, deodorants and conditioners.
Decamethylcyclopentasiloxane is also used in various applications such as industrial cleaning fluids and dry cleaning solvents.
Decamethylcyclopentasiloxane is a precursor in the production of siloxane polymers for industry and medicine and is a carrier ingredient in many toiletries and cosmetics.
Decamethylcyclopentasiloxane has a relatively low order of toxicity following acute administration via the oral, dermal, and inhalation routes of exposure.
Decamethylcyclopentasiloxane is not considered to be a dermal or eye irritant or a dermal sensitizer.
There is no appreciable dermal absorption of Decamethylcyclopentasiloxane based on results from in vivo and in vitro studies.
Decamethylcyclopentasiloxane has not been shown to be genotoxic/mutagenic when tested in a number of short-term in vitro and in vivo assays and did not cause reproductive or developmental toxicity in rats.
Inhalation exposure of rats to 160 ppm Decamethylcyclopentasiloxane for up to 24 months produced adverse effects in the liver (weight changes and hepatocellular hypertrophy) and uterus (increased incidence of endometrial adenocarcinoma, endometrial adenoma, and adenomatous polyps in several animals); however, the results of recent mode-of-action studies are consistent with a uterine tumorigenesis mechanism that is not relevant for humans.
Based on the results of the chronic inhalation study, 160 ppm was determined to be the no-observed-adverse-effect level (NOAEL) and was selected as the point of departure for the derivation of the workplace environmental exposure level (WEEL) value.
This NOAEL was adjusted to account for interindividual variability and residual uncertainty regarding upper respiratory tract changes still occurring at 160 ppm.
The resulting 8-h time-weighted average WEEL value of 10 ppm is expected to provide a significant margin of safety against any potential adverse health effects in workers exposed to airborne Decamethylcyclopentasiloxane.
Decamethylcyclopentasiloxane is a cyclic siloxane used in the formulation of consumer products as well as an industrial intermediate.
A summary of the previous studies on the toxicology of Decamethylcyclopentasiloxane is provided.
Toxicokinetic studies with Decamethylcyclopentasiloxane after dermal administration demonstrate a very low uptake of due to rapid evaporation.
Following inhalation exposure, exhalation of unchanged Decamethylcyclopentasiloxane and excretion of metabolites with urine are major pathways for clearance in mammals.
Due to this rapid clearance by exhalation, the potential for bioaccumulation of Decamethylcyclopentasiloxane is considered unlikely.
The available toxicity data on Decamethylcyclopentasiloxane adequately cover the relevant endpoints regarding potential human health hazards.
Decamethylcyclopentasiloxane was not DNA reactive or mutagenic in standard in vitro and in vivo test systems.
Decamethylcyclopentasiloxane also did not induce developmental and reproductive toxicity in appropriately performed studies.
In repeated studies in rats with subacute, subchronic and chronic inhalation exposure, mild effects on the respiratory tract typically seen after inhalation of irritating materials, increases in liver weight (28- and 90-day inhalation studies), and a small increase in the incidence of uterine adenocarcinoma (uterine tumor) in female rats (two-year inhalation chronic bioassay) were observed.
The liver effects induced by Decamethylcyclopentasiloxane were consistent with D5 as a weak “phenobarbital-like” inducer of xenobiotic metabolizing enzymes and these effects are considered to be an adaptive response.
Mechanistic studies to elucidate the mode-of-action for uterine tumor induction suggest an interaction of Decamethylcyclopentasiloxane with dopamine signal transduction pathways altering the pituitary control of the estrus cycle.
The resulting estrogen imbalance may cause the small increase in uterine tumor incidence at the highest Decamethylcyclopentasiloxane-exposure concentration over that seen in control rats.
A genotoxic mechanism or a direct endocrine activity of Decamethylcyclopentasiloxane is not supported as a mode-of-action to account for the induction of uterine tumors by the available data.
Uses of Decamethylcyclopentasiloxane:
Decamethylcyclopentasiloxane is a cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products.
Decamethylcyclopentasiloxane is used in dermal exposure and inhalation toxicity study.
Decamethylcyclopentasiloxane is used intermediate in the manufacture of high mol wt siloxane polymers.
Decamethylcyclopentasiloxane is a carrier ingredient in personal care products; dry cleaning solvent.
Decamethylcyclopentasiloxane is incorporated into a formulation for its emollient and solvent activity.
Octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
Decamethylcyclopentasiloxane is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Decamethylcyclopentasiloxane is considered an emollient.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Decamethylcyclopentasiloxane is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of Decamethylcyclopentasiloxane in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Decamethylcyclopentasiloxane used in dermal exposure and inhalation toxicity study.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
Decamethylcyclopentasiloxane is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Decamethylcyclopentasiloxane is considered an emollient.
In Canada, among the volume used in Decamethylcyclopentasiloxane approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of Decamethylcyclopentasiloxane is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of Decamethylcyclopentasiloxane in the Northern Hemisphere were estimated to 30,000 tonnes per year.
Decamethylcyclopentasiloxane is used in personal care products including skin creams, cosmetics, shampoos, deodorants and conditioners.
Decamethylcyclopentasiloxane is also used in various applications such as industrial cleaning fluids and dry cleaning solvents.
Decamethylcyclopentasiloxane is used in conditioners, hair sprays, face wash, body wash, make-up, sun care.
Decamethylcyclopentasiloxane is used in antiperspirants and deodorants.
Decamethylcyclopentasiloxane is commonly used in cosmetics such as deodorants, sunscreens, hair sprays, and skin care products.
Decamethylcyclopentasiloxane is becoming more common in conditioners, as Decamethylcyclopentasiloxane does, hair becomes easier to comb without breaking.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Decamethylcyclopentasiloxane is considered an emollient.
Decamethylcyclopentasiloxane can be used as: A greener solvent in synthetic chemistry applications.
Decamethylcyclopentasiloxane is a silicone fluid widely used in cosmetics such as deodorants, sunscreens, hair sprays.
Like all other silicones, Decamethylcyclopentasiloxane has a unique fluidity that spreads easily.
Decamethylcyclopentasiloxane, when applied to the skin and hair, feels silky and soft to the touch and acts as a preservative.
Decamethylcyclopentasiloxanes are used in silicone fluids, elastomers and used in resins.
Decamethylcyclopentasiloxane is widely used in cosmetic and body care products such as skin care, sunscreen, makeup, hair.
Decamethylcyclopentasiloxane is directly used as carrier, is the main raw material, can also be used as additive; and being Used in aqueous systems by emulsification method.
Decamethylcyclopentasiloxane is widely used in applications such as antiperspirants, deodorants, hair sprays, cleaning.
Decamethylcyclopentasiloxane is widely used in applications such as antiperspirants, deodorants, hair sprays, cleaning.
Decamethylcyclopentasiloxane is actually a type of silicone that is regularly used in skin care and hair care products.
Decamethylcyclopentasiloxane is part of a particularly small group of silicon: cyclomethicones are also used.
According to clinical studies and reports, Decamethylcyclopentasiloxane is considered safe for cosmetic ingredient uses.
Decamethylcyclopentasiloxane is an odorless, colorless, non-oily liquid used in personal care products and as a dry ingredient.
Decamethylcyclopentasiloxane is commonly used as an ingredient in lubricants and sealants.
Decamethylcyclopentasiloxane is used in Adhesives and Sealants, Chemical Synthesis, Construction Chemicals, Glass and Ceramics, Industrial Chemicals, Silicones and Silanes, Coatings.
Decamethylcyclopentasiloxane is used in Coatings, Adhesives, Sealants and Elastomers, Chemical and Materials Manufacturing, Construction and Building Materials, Surface Treatment - Fluids, Lubricants and Metalworking.
A base fluid with excellent spreading, easy rubbing and lubricating properties found in many personal care products has unique volatility properties.
Decamethylcyclopentasiloxane is used in antiperspirants, deodorants, hair sprays, cleaning creams, skin creams, lotions and stick products, bath oils, sun and shaving products, make-up materials, nail polishes.
Decamethylcyclopentasiloxane in rods has the right balance between volatility and diffusion.
Decamethylcyclopentasiloxane is classified as a cyclomethicone.
Decamethylcyclopentasiloxane is widely used in cosmetics such as deodorants, sunscreens, hair sprays, and skin care.
Decamethylcyclopentasiloxane is becoming more common in conditioners, as Decamethylcyclopentasiloxane does, hair becomes easier to comb without breaking.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Decamethylcyclopentasiloxane is considered an emollient.
Decamethylcyclopentasiloxane is used as a skin emollient in cosmetics and personal products.
Decamethylcyclopentasiloxane is used in cosmetics such as deodorants, sunscreens, hair sprays, and personal care.
In addition, Decamethylcyclopentasiloxane is used in silicone-based personal lubricants.
Also, Decamethylcyclopentasiloxane is a cyclic volatile methylsiloxane used in conditioners so it is also used in hair brushes.
Decamethylcyclopentasiloxane is a cyclic volatile methylsiloxane (cVMS) used in cosmetics and personal care products.
Decamethylcyclopentasiloxane is also used in a dermal exposure and inhalation toxicity study.
Decamethylcyclopentasiloxane is used in personal care products including skin creams, cosmetics, shampoos.
Decamethylcyclopentasiloxane is also used in a variety of applications such as industrial cleaning fluids and dry cleaning.
Decamethylcyclopentasiloxane is used as an intermediate in the production of high molecular weight siloxane polymers.
Decamethylcyclopentasiloxane is used as a carrier in personal care products.
Decamethylcyclopentasiloxane is used as a dry cleaning solvent.
Decamethylcyclopentasiloxane is included in a formulation for softener and solvent of Decamethylcyclopentasiloxane.
Decamethylcyclopentasiloxane and decamethylcyclopentasiloxane are the main marketed industrial products.
Decamethylcyclopentasiloxane is used in the production of some silicone-based polymers that are widely used in various industries.
Pharmaceutical secondary standards for application in quality control provide pharmaceutical laboratories and manufacturers with a convenient and cost-effective alternative to establishing in-house working standards.
Decamethylcyclopentasiloxane is widely used in cosmetics such as deodorants, sunscreens, hair sprays, and skin care.
Decamethylcyclopentasiloxane is becoming more common in conditioners because D5 siloxane makes hair easier to comb through.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Decamethylcyclopentasiloxane is considered an emollient.
Decamethylcyclopentasiloxane can be used as a carrier solvent in pharmaceutical formulations, assisting in the dispersion of active ingredients and enhancing drug delivery.
Decamethylcyclopentasiloxane can be utilized in the production of polymer materials, including plastics, as a processing aid, lubricant, or release agent.
Decamethylcyclopentasiloxane's lubricating properties make it suitable for use in industrial lubricants and machinery where its low viscosity and thermal stability are advantageous.
Decamethylcyclopentasiloxane's used to modify the viscosity and improve the application properties of adhesives and sealants, contributing to their performance.
Decamethylcyclopentasiloxane is used as a dielectric fluid in various electrical applications, such as cooling transformers and insulating components in the electronics industry.
Decamethylcyclopentasiloxane can be found in lubricants and protective coatings used in the automotive and aerospace sectors.
Decamethylcyclopentasiloxane can be added as an ingredient to silicone blends used in cosmetic applications.
Decamethylcyclopentasiloxane is used in skin creams and sunscreens, where siloxane may be labeled "cyclomethicone" or "cyclopentasiloxane."
Decamethylcyclopentasiloxane can also be used as a dry cleaning solvent in closed systems, which is considerably limited.
Decamethylcyclopentasiloxane is used as an alternative to tetrachlorethylene in dry cleaning and industrial cleaning.
Decamethylcyclopentasiloxane is a cyclic siloxane used in the formulation of consumer products and industrially.
Decamethylcyclopentasiloxane is a precursor in the production of siloxane polymers for industry and medicine and is a carrier in many toiletries and cosmetics.
Decamethylcyclopentasiloxane is found or used in the manufacture of a wide variety of products.
The predominant use of Decamethylcyclopentasiloxane siloxane worldwide and in Canada is in the blending and formulation of consumer products.
Decamethylcyclopentasiloxane is also used in the production of silicone polymers.
Decamethylcyclopentasiloxane is used in hair/skin care products, antiperspirants and similar personal care products.
Decamethylcyclopentasiloxane is used for excellent spreading, rapid evaporation leaving no residue or build-up, unique feeling of softness and lubricity.
Decamethylcyclopentasiloxane is non greasy, non-occlusive and non-irritating.
Decamethylcyclopentasiloxane is used in industrial processes (for example, as a surfactant in some pesticide products) and as a defoamer), lubricants, cleaning products, sealants, adhesives, waxes, lacquers and coatings.
Decamethylcyclopentasiloxane is widely used as a volatile excipient in cosmetic products.
A growing number of commercial dry cleaners in Canada are using Decamethylcyclopentasiloxane as their dry cleaning fluid.
Decamethylcyclopentasiloxane is widely used in cosmetic products due to the unique functions of D5 siloxane as an antistatic.
Decamethylcyclopentasiloxane is widely used in many cosmetic products for the following reasons: thanks to its low surface tension Decamethylcyclopentasiloxane is also used to spread rapidly on the skin and hair.
Decamethylcyclopentasiloxane has hydrophobicity, Decamethylcyclopentasiloxane has volatility (Decamethylcyclopentasiloxane evaporates from skin or hair within 4-12 hours after application), and Decamethylcyclopentasiloxane has stability.
Decamethylcyclopentasiloxane can have many different functions in cosmetic products.
Decamethylcyclopentasiloxane is becoming more common in conditioners because it makes it easier to brush the hair.
Decamethylcyclopentasiloxane is also used as part of silicone-based personal lubricants.
Cosmetic uses:
Decamethylcyclopentasiloxane can be frustrating to decipher the long chemical names on the label of your favorite cosmetic products.
Simple ingredients like water and alcohol are easy to recognize.
But lengthy chemical names can leave even the most conscious consumers scratching their heads.
Decamethylcyclopentasiloxane is used in hundreds of cosmetics.
In the past, there was controversy about Decamethylcyclopentasiloxane's potential health and environmental risks.
But the Cosmetic Ingredient Review Expert Panel considers Decamethylcyclopentasiloxane safe to use in cosmetics.
However, in early 2018 the European Union introduced restrictions on Decamethylcyclopentasiloxane use in cosmetic products that are intended to be washed off before evaporation.
Concentrations above 0.1% in wash-off products were determined to have a risk of accumulating in the water supply.
Applications of Decamethylcyclopentasiloxane:
Decamethylcyclopentasiloxane-d30 is a deuterated version of Decamethylcyclopentasiloxane (D212440).
Decamethylcyclopentasiloxane is a cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products.
Decamethylcyclopentasiloxane was also used in a dermal exposure and inhalation toxicity study.
Decamethylcyclopentasiloxane can be used as:
A greener solvent in synthetic chemistry applications.
A monomeric unit for polymerization by various base catalysts to obtain polysiloxane polymer.
Other Applications:
Creams, lotions & gels
Decorative cosmetics/Make-up > Nail polishes
Hair care (Shampoos, Conditioners & Styling) > Styling/Hair sprays
Sun care (Sun protection, After-sun & Self-tanning) > Self tanning products
Toiletries (Shower & Bath, Oral care...) > Antiperspirants & deodorants
Toiletries (Shower & Bath, Oral care...) > Shaving
Features of Decamethylcyclopentasiloxane:
Volatile carrier
Compatible with a wide range of cosmetic ingredients
Low surface tension
Imparts soft silky feel to the skin
Excellent spreading
Leaves no oily residue or build up
Detackification
Non-greasy
Production and polymerization of Decamethylcyclopentasiloxane:
Commercially Decamethylcyclopentasiloxane is produced from dimethyldichlorosilane.
Hydrolysis of the dichloride produces a mixture of cyclic dimethylsiloxanes and polydimethylsiloxane.
From this mixture, the cyclic siloxanes including Decamethylcyclopentasiloxane can be removed by distillation.
In the presence of a strong base such as KOH, the polymer/ring mixture is equilibrated, allowing complete conversion to the more volatile cyclic siloxanes:
[(CH3)2SiO]5n → n [(CH3)2SiO]5
where n is a positive integer.
D4 and Decamethylcyclopentasiloxanes are also precursors to the polymer.
The catalyst is again KOH.
History of Decamethylcyclopentasiloxane:
Decamethylcyclopentasiloxane, a type of cyclic siloxane, has a history tied to the development of organosilicon chemistry in the 20th century.
Silicones, as a broader class, were first synthesized in the early 1900s, with significant contributions from British chemist Frederick Kipping, who studied organic silicon compounds.
However, Decamethylcyclopentasiloxane wasn’t until the mid-20th century that cyclic siloxanes, including D5, were produced and became prominent in industrial applications.
D5, with Decamethylcyclopentasiloxane's unique chemical structure, consisting of five silicon-oxygen units in a ring, was found to have exceptional stability and low surface tension, which made it highly desirable for various commercial uses.
By the 1980s and 1990s, Decamethylcyclopentasiloxane became widely used in personal care products, including deodorants, hair sprays, and skin lotions, due to its volatility, smooth texture, and non-greasy feel.
Environmental and health concerns surrounding Decamethylcyclopentasiloxane started to emerge in the early 2000s as researchers began investigating the compound's potential to persist in the environment and bioaccumulate in organisms.
Despite Decamethylcyclopentasiloxane's widespread use, regulatory bodies in different parts of the world, such as the European Chemicals Agency (ECHA) and Environment Canada, began reviewing its safety.
Over the years, studies have led to varied conclusions, with some research suggesting minimal environmental impact, while other investigations raised concerns about Decamethylcyclopentasiloxane’s long-term effects.
The regulatory status of Decamethylcyclopentasiloxane continues to evolve as more research is conducted, balancing its industrial importance with environmental safety.
Handling and Storage of Decamethylcyclopentasiloxane:
Handling:
Avoid inhalation, ingestion, and skin or eye contact.
Use in well-ventilated areas and minimize aerosol formation.
Handle with care to prevent spills and ensure proper containment to avoid release into the environment.
Storage:
Store in a cool, dry, well-ventilated place.
Keep containers tightly closed and away from direct sunlight, heat sources, and incompatible materials like strong oxidizers.
Maintain in original packaging or appropriate containers made of suitable materials.
Stability and Reactivity of Decamethylcyclopentasiloxane:
Stability:
Decamethylcyclopentasiloxane is stable under normal temperature and pressure conditions.
Decamethylcyclopentasiloxane is resistant to hydrolysis and oxidation in neutral or slightly alkaline environments.
Reactivity:
Avoid contact with strong acids, bases, and oxidizing agents as they can break down the silicone structure.
Decomposition products under fire conditions may include carbon oxides and formaldehyde.
Hazardous Decomposition Products:
Thermal decomposition or combustion can produce hazardous fumes including carbon monoxide, carbon dioxide, and silicon dioxide.
First Aid Measures of Decamethylcyclopentasiloxane:
Inhalation:
Move the person to fresh air.
If breathing difficulties persist, seek medical attention.
Skin Contact:
Wash skin thoroughly with soap and water.
Remove contaminated clothing.
Seek medical advice if irritation occurs.
Eye Contact:
Immediately rinse eyes with water for several minutes.
If irritation persists, consult a doctor.
Ingestion:
Do not induce vomiting.
Rinse mouth with water and seek medical help if large amounts are ingested.
Firefighting Measures of Decamethylcyclopentasiloxane:
Extinguishing Media:
Use water spray, foam, dry chemical, or carbon dioxide for extinguishing fires involving Decamethylcyclopentasiloxane.
Specific Hazards:
In a fire, Decamethylcyclopentasiloxane may decompose and release harmful combustion products like silicon dioxide, carbon oxides, and formaldehyde.
Protective Equipment:
Firefighters should wear full protective clothing, including a self-contained breathing apparatus (SCBA), to avoid exposure to fumes and decomposition products.
Accidental Release Measures of Decamethylcyclopentasiloxane:
Personal Precautions:
Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and suitable protective clothing to prevent skin and eye contact.
Environmental Precautions:
Avoid release into waterways, drains, or soil.
Decamethylcyclopentasiloxane may persist in the environment, so take care to limit its spread.
Cleanup Methods:
For small spills, absorb with inert materials (e.g., sand, earth) and place into appropriate containers for disposal.
For large spills, contain and collect the material for recycling or disposal in compliance with local regulations.
Exposure Controls / Personal Protective Equipment of Decamethylcyclopentasiloxane:
Engineering Controls:
Ensure adequate ventilation, particularly in enclosed areas.
Local exhaust ventilation is recommended if misting occurs.
Personal Protective Equipment:
Eye Protection:
Safety glasses or goggles are recommended.
Skin Protection:
Use chemical-resistant gloves and long-sleeved clothing to minimize skin contact.
Respiratory Protection:
If ventilation is inadequate, use an appropriate respiratory protection device.
Hygiene Measures:
Wash hands after handling Decamethylcyclopentasiloxane and before eating or drinking.
Remove contaminated clothing and wash before reuse.
Identifiers of Decamethylcyclopentasiloxane:
CAS Number: 541-02-6
Beilstein Reference: 1800166
ChEMBL: 1885178
ChemSpider: 10451
DrugBank: DB11244
ECHA InfoCard: 100.007.969
EC Number: 208-764-9
MeSH: Decamethylcyclopentasiloxane
PubChem CID: 10913
RTECS number: GY5945200
UNII: 0THT5PCI0R
CompTox Dashboard (EPA): DTXSID1027184
IUPAC Name: 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Alternative Names: DECAMETHYLCYCLOPENTASILOXANE
Molecular Formula: C10H30O5Si5
Molar Mass: 370.77 g/mol
InChI: InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
InChI Key: XMSXQFUHVRWGNA-UHFFFAOYSA-N
Empirical Formula (Hill Notation): C10H30O5Si5
CAS Number: 541-02-6
Molecular Weight: 370.77
Beilstein: 1800166
EC Number: 208-764-9
MDL number: MFCD00046966
PubChem Substance ID: 24868110
Properties of Decamethylcyclopentasiloxane:
Chemical formula: [(CH3)2SiO]5
Molar mass: 370.770 g·mol−1
Appearance : Colourless liquid
Density: 0.958 g/cm3
Melting point: −47 °C; −53 °F; 226 K
Boiling point: 210 °C (410 °F; 483 K)
Solubility in water: 17.03±0.72 ppb (23 °C)
log P: 8.07
Vapor pressure: 20.4±1.1 Pa (25 °C)
Viscosity: 3.74 cP
Vapor density: 6.8
Flash point: 82.7°C (180.86°F) at 101.3 kPa
Flammability limits: Nonflammable
Autoignition temperature: 372°C (701.60°F) at 101.3 kPa
Specific gravity: 0.959 g/cm3 at 20°C (68°F)
Solubility: 17 µg/L at 23°C (73°F) in water; soluble in ethanol, ether, acetone, and benzene; very soluble in pyridine
Partition coefficient: (log Kow) 8.02 at 25.3°C
Stability: Stable
Reactivities and incompatibilities: Oxidizing agents
Quality Level: 100
assay: 97%
form: liquid
refractive index: n20/D 1.396 (lit.)
bp: 90 °C/10 mmHg (lit.)
density: 0.958 g/mL at 25 °C (lit.)
SMILES string: C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1
InChI: 1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
InChI key: XMSXQFUHVRWGNA-UHFFFAOYSA-N
Molecular Weight: 370.77
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 0
Exact Mass: 370.09395673
Monoisotopic Mass: 370.09395673
Topological Polar Surface Area: 46.2 Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 258
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
