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CORYDALIS YANHUSUO TUBER EXTRACT

Corydalis Yanhusuo Tuber Extract, a precious herb of the Papaveraceae family, is widely used in multiple traditional Chinese medicines for the treatment of many painful conditions, and its medicinal part is the dried tuber.


CAS Number: 84696-18-6
EC Number: 283-920-9
Family: Papaveraceae
Genus: Corydalis
Species: C. yanhusuo
Binomial name
Corydalis yanhusuo
Botanical names: Corydalis turtschaninovii, Corydalis yanhusuo



SYNONYMS:
Corydale, Corydale Bulbeuse, Corydale Creuse, Corydale à Tubercule Creux, Corydalis Yanhusuo Rhizome, Dai Ding, Early Fumitory, Fumeterre Creuse, Squirrel Corn, Xuanhu, Yanhu, Yanhusuo, Yuan-hu, Yuanhu, Yuan Hu Suo, Corydalis yanhusuo, Corydalis turtschaninovii, Corydalis yanhusuo extract, Yanhusuo extract, Corydalis tuber extract, Corydalis root extract, Corydalis yanhusuo tuber, Yanhusuo, Chinese corydalis, Pinyin: Yán hū suǒ, Corydale, Corydale Bulbeuse, Corydale Creuse, Corydale à Tubercule Creux, Corydalis Yanhusuo Rhizome, Dai Ding, Early Fumitory, Fumeterre Creuse, Squirrel Corn, Xuanhu, Yanhu, Yanhusuo, Yuan-hu, Yuanhu, Corydalis yanhusuo, Corydalis turtschaninovii, Corydalis yanhusuo extract, Yanhusuo extract, Corydalis tuber extract, Corydalis root extract, Chinese corydalis



Corydalis Yanhusuo Tuber Extract, a precious herb of the Papaveraceae family, is widely used in multiple traditional Chinese medicines for the treatment of many painful conditions, and its medicinal part is the dried tuber. 
Yet how to improve this plant’s medicinal yield as well as Corydalis Yanhusuo Tuber Extract's economic efficiency remains a key problem in its cultivation. 


The planting of Corydalis Yanhusuo Tuber Extract in rotation with peanut (Arachis hypogaea L.) aims to improve land utilization efficiency, but the total production of tubers is severely reduced relative to fields without rotation. 
However, an increased yield was observed in Corydalis Yanhusuo Tuber Extract plants grown in previously flooded fields (HR field) compared to the ones grown in the fields that had been used to cultivate peanut (PL field) or in fields without rotation or flooding (N field). 


Based on these phenomena, in this study, we explored the potential factors responsible for the altered growth/yield of Corydalis Yanhusuo Tuber Extract under different field conditions. 
Soil physicochemical properties and the diversity and community of rhizobacteriome of Corydalis Yanhusuo Tuber Extract were both analyzed. 


By testing several soil physicochemical properties, we found that the cation exchange capacity (CEC), soil organic matter (SOM), total nitrogen (TN), and pH value differed significantly among these three types of fields. 
16S rRNA amplicon sequencing revealed stark differences in the composition, diversity, and potential functions of the bacterial community in the rhizosphere of Corydalis Yanhusuo Tuber Extract plants grown in field with the peanut rotation or flooding. 


Notably, the Acidobacteria were enriched in the HR field, while Actinobacteria were enriched in the PL field. 
More importantly, further analysis showed that changed soil physicochemical properties could be one reason for why the rhizospheric bacterial community has changed; hence, soil physicochemical properties might also be affecting plant performance indirectly by regulating the rhizospheric bacterial community. 


The RDA analysis distinguished CEC as the most important soil physicochemical property influencing the structure and composition of the Corydalis Yanhusuo Tuber Extract rhizobacteriome. 
In summary, our results suggest peanut rotation- and flooding-induced soil physicochemical properties changes would further impact the rhizobacteriome of 

Corydalis Yanhusuo Tuber Extract albeit differentially, culminating in opposite effects upon the plant growth and medicinal yield of Corydalis Yanhusuo Tuber Extract.
Corydalis Yanhusuo Tuber Extract is flowering plant that grows in mild climates throughout the northern hemisphere. 


People use Corydalis Yanhusuo Tuber Extract for constipation, indigestion, acid reflux, headache, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse Corydalis Yanhusuo Tuber Extract with other species that might be generally called Corydalis. 


These are not the same.
Corydalis Yanhusuo Tuber Extract is a plant species in the genus Corydalis. 
The Chinese name for Corydalis Yanhusuo Tuber Extract is yan hu suo (Chinese: 延胡索; pinyin: yán hú suǒ; lit. 'extended barbarian rope'). 


The Japanese common name is engosaku (エンゴサク) and the Korean common name is hyeonhosaek (현호색). 
English common names include yanhusuo, corydalis, and Asian corydalis. 
The tuber of this plant, frequently mislabeled as the root, is an important therapeutic agent in traditional Chinese medicine. 


It is native to high-altitude grasslands across China including in the provinces of Anhui, Henan, Hubei, Hunan, Jiangsu, and Zhejiang, but is more widely cultivated.
According to the Flora of China, this perennial herbaceous plant produces 5 to 15 purple-blue tubular flowers in clusters that curve out at the opening. 


The yellow, round tubers are up to 2.5 cm (1 in) in diameter.
The corydalis plant has five to 15 purple-blue-hued flowers clustered together that curve outward. 
It’s in the Papaveraceae family (commonly known as poppies).


Corydalis Yanhusuo Tuber Extract is an herb native to the Chinese province of Zhejiang. 
The portion of Corydalis Yanhusuo Tuber Extract that is used medicinally is the tuberous rhizome
Corydalis Yanhusuo Tuber Extract is a member of the Poppy family, and is closely related to the Opium Poppy. 


In traditional Chinese medicine, Corydalis Yanhusuo Tuber Extract is said to invigorate the blood, move qi or energy traveling through the body, and decrease pain, especially with menstrual cramps, abdominal cramping, and hernias.
There are over 400 different Corydalis Yanhusuo species. 


This perennial plant is a low growing plant that produces small trumpet-like flowers that vary in color from white to pink to blue, depending upon the species. 
The leaf shapes vary by species as does the height of growth.


Corydalis Yanhusuo Tuber Extract isn’t an herb you hear about every day in North America. 
For example, the root of Corydalis Yanhusuo Tuber Extract has long been prized by traditional herbalists for its cleansing actions, and Traditional Chinese Medicine doctors rely on it to help support the flow of Qi (the flow of energy throughout the body, pronounced “chee”) and movement of fluids.


However, Corydalis Yanhusuo Tuber Extract is highly prized as a functional herb in Traditional Chinese Medicine and other Traditional wellness practices in Asia.
The Corydalis Yanhusuo Tuber Extract includes over 400 species belonging to the poppy family. 


Its name comes from the Greek word “korydalis,” meaning “crested lark,” which refers to how the plant resembles the lark’s crest via its tube-like flowers.
Corydalis Yanhusuo Tuber Extract is flowering plant that grows in mild climates throughout the northern hemisphere. 
Don't confuse Corydalis Yanhusuo Tuber Extract with other species that might be generally called Corydalis. 



USES and APPLICATIONS of CORYDALIS YANHUSUO TUBER EXTRACT:
Corydalis Yanhusuo Tuber Extract is used for mild depression, and Mental and emotional disturbances.
Corydalis Yanhusuo Tuber Extract is used severe nerve damage, Tremors, and High blood pressure.
Corydalis Yanhusuo Tuber Extract is used intestinal spasms, and Other conditions.


More evidence is needed to rate the effectiveness of Corydalis Yanhusuo Tuber Extract for these uses.
Cosmetic Uses of Corydalis Yanhusuo Tuber Extract: antioxidants
Corydalis Yanhusuo Tuber Extract is used for mild depression, mild mental disorders, emotional disturbances, severe nerve damage, and limb tremors. 


Corydalis Yanhusuo Tuber Extract is also used as a mild sedative and tranquilizer, as a hallucinogen, to lower blood pressure, and to relax spasms in the small intestine.
Corydalis Yanhusuo Tuber Extract is used in traditional Chinese Medicine (TCM).


The root and tuber of the Corydalis Yanhusuo Tuber Extract are used in medicine. 
Corydalis Yanhusuo Tuber Extract contains chemicals that might help fight certain infections in the stomach.
Corydalis Yanhusuo Tuber Extract is often used in combination with other herbal supplements that claim health benefits. 


There isn't any research, though, that has proven the safety or efficacy of Corydalis Yanhusuo Tuber Extract, and side effects and risks have been indicated.
Corydalis Yanhusuo Tuber Extract prevents morphine tolerance and dependence while also reversing opiate addiction, according to a recent study led by the University of California, Irvine. 


The documented effects of YHS, Corydalis Yanhusuo Tuber Extract of the plant Corydalis Yanhusuo Tuber Extract, could have an immediate, positive impact to curb the opioid epidemic.
A possible solution consists of a co-medication that maintains the analgesic benefits of opioids while preventing their adverse liabilities. 


The research findings show that Corydalis Yanhusuo Tuber Extract, when coadministered with morphine, inhibits morphine tolerance, dependence and addiction. 
If Corydalis Yanhusuo Tuber Extract is used with morphine at the start or during pain management, there will be less need of morphine and thus less risk of addiction.


Corydalis Yanhusuo Tuber Extract has been used as analgesic in traditional Chinese medicine for centuries. 
Corydalis Yanhusuo Tuber Extract is considered safe and readily available for purchase, either online or as a “botanical” in certain grocery stores. 
Root extracts from the flowering herbal plant Corydalis Yanhusuo Tuber Extract, or YHS, has widely used for centuries as a pain treatment. 


Yet few studies have investigated how Corydalis Yanhusuo Tuber Extract works on different forms of pain, and little is known about its molecular mechanisms. 
However, Corydalis Yanhusuo Tuber Extract has been used for thousands of years in Traditional Chinese Medicine and for centuries in North America and other countries for its beneficial and protective properties.


Corydalis Yanhusuo Tuber Extract was also used extensively by Eclectic Physicians practicing in North America in the mid to late 1800s as an alternative or "cleansing" herb to support liver function and detoxification.
Corydalis grows in forests, and its bright yellow root or tuber (rich in alkaloids) is used in traditional herbal preparations and supplements. 


Corydalis Yanhusuo Tuber Extract's used in traditional Chinese Medicine (TCM).
Corydalis Yanhusuo Tuber Extract is used in medicine. 
In a new study, researchers show how Corydalis Yanhusuo Tuber Extract effectively treats different forms of pain.


Corydalis Yanhusuo Tuber Extract contains chemicals that might help fight certain infections in the stomach.
People use Corydalis Yanhusuo Tuber Extract for constipation, indigestion, acid reflux, headache, and many other conditions, but there is no good scientific evidence to support these uses.


-Traditional Uses Of Corydalis Yanhusuo Tuber Extract:
As mentioned above, Corydalis Yanhusuo Tuber Extract has a long history of use in the Northern Hemisphere, particularly in the Traditional Medicine systems of Asia, such as China, Japan, Korea, Russia, and North America.

Some traditional uses of Corydalis Yanhusuo Tuber Extract include: Blood function support, Cognitive support, Digestive support, Heart support, Liver support, Nervous system support, For easing menstrual cramps, For minor pain management, For overall menstruation support, To move stagnant Qi, To promote normal fluid movement and balance, To promote relaxation, To support emotional health, Spleen and stomach stasis.

Today, Corydalis Yanhusuo Tuber Extract is still used extensively in Traditional Chinese Medicine and other systems of herbalism but has yet to be studied as extensively as other herbs, like Turmeric or Ashwagandha.



CORYDALIS YANHUSUO TUBER EXTRACT CONTAINS: 
Research has shown Corydalis Yanhusuo Tuber Extract contains over 160 compounds, including: 
Alkaloids
Antioxidants
Organic acids
Volatile oils
Amino acids
Nucleosides
Alcohols
And sugars 

Alkaloids, which give the root its brilliant yellow color, are considered the most crucial active constituents, with over 80 types isolated and identified. 
Corydalis Yanhusuo Tuber Extract is also a source of Berberines, a specific plant compound known as an isoquinoline alkaloid found in the barks, leaves, twigs, rhizomes, roots, and/or stems of approximately 450–500 plant species.
Berberines have become popular due to their potential benefits for various aspects of metabolic, immune, and inflammatory function. 



HISTORY OF CORYDALIS YANHUSUO TUBER EXTRACT:
Yanhusuo is first mentioned in Ben Cao Shi Yi (Omissions from the Materia Medica), written by Chen Cang-Qi in 720 CE.



CHEMICAL COMPOUNDS OF CORYDALIS YANHUSUO TUBER EXTRACT:
The alkaloid dehydrocorybulbine (DHCB) can be extracted from the roots of the plant. 
Tetrahydropalmatine is another major constituent alkaloid.

Corydalis Yanhusuo Tuber Extract also contains the alkaloids glaucine and palmatine.
Corydalis Yanhusuo Tuber Extract also contains the acetylcholinesterase inhibitor corydaline.
N-Methyltetrahydroprotoberberines have been isolated from C. yanhusuo.



6 BENEFITS OF CORYDALIS YANHUSUO TUBER EXTRACT:
As you’ve just learned, Corydalis Yanhusuo Tuber Extract has many uses in traditional herbalism and wellness practices and has been revered for centuries.
However, the science behind this ancient herb, Corydalis Yanhusuo Tuber Extract, is still in its infancy.

Here, we examine the emerging research behind six potential benefits of Corydalis Yanhusuo Tuber Extract for minor pain management, relaxation, cognitive function, and more.


#1: Corydalis Yanhusuo Tuber Extract May Help with Minor Pain Management
Corydalis Yanhusuo Tuber Extract is widely used for minor pain management throughout Asia and, more recently, in North America.

But does it work?
Several animal studies suggest Corydalis Yanhusuo Tuber Extract may have analgesic properties that work via its effects on the nervous system and dopamine, a neurotransmitter associated with pleasure, comfort, and decreased pain.

Researchers also believe various alkaloids in Corydalis Yanhusuo Tuber Extract, which promote normal inflammatory response, may be involved in its effects on pain.

Although more research is needed, Corydalis Yanhusuo Tuber Extract’ use for minor pain management is well-documented in Traditional Chinese Medicine texts and anecdotal evidence for its efficacy is strong.


#2: Corydalis Yanhusuo Tuber Extract May Support Heart & Cardiovascular Function
We now know that a normal and healthy inflammatory response is critical to heart and cardiovascular function. 

This is why most doctors now recommend taking measures to support a healthy inflammatory response as part of a heart-healthy lifestyle, like reducing stress, eating plenty of fruits and vegetables, getting regular exercise, and reducing intake of processed foods and alcohol.
Studies have also found various herbs, including berberine-containing herbs, may help support normal heart and cardiovascular function. 

This includes Corydalis Yanhusuo Tuber Extract, which studies suggest may benefit normal cardiovascular function, either directly or indirectly, via its supportive effects on: 
*Heart rate
*Inflammatory response via its antioxidant compounds
*Normal blood pressure
*Liver function (the liver plays a primary role in cholesterol synthesis)
*Stress response/nervous system function
More research is needed to recommend Corydalis for heart health.


3: Corydalis Yanhusuo Tuber Extract May Provide Liver Support Benefits
Berberine-containing plants, specifically roots like Dandelion, Goldenseal, and Corydalis Yanhusuo Tuber Extract, have long been used by herbalists in liver-supportive formulas.

It is believed the signature yellow color and astringent, bitter properties have a cleansing and protective effect on the liver and other organs of detoxification.

A large body of research has shown Berberine may support various aspects of liver function, including bile synthesis, inflammatory response, lipid metabolism, and oxidation resistance: 
Regarding Corydalis Yanhusuo Tuber Extract, research has shown its Berberine isoquinoline compounds may have liver-protective properties.

Although more studies are needed to fully understand how Corydalis Yanhusuo Tuber Extract may support the liver, this emerging research is consistent with Cordylasis’ use as a liver support herb in various Traditional Chinese Medicine and North American eclectic herbal formulas.


#4: Corydalis Yanhusuo Tuber Extract May Promote Feelings of Relaxation
One of Corydalis Yanhusuo Tuber Extract’ claims to fame is its purported relaxation effect, which advocates say can help reduce stress, support the nervous system, boost emotional well-being, and promote cognitive function.
There is research to suggest Corydalis Yanhusuo Tuber Extract does have a mild sedative effect and may be helpful for relaxation, stress, and healthy sleep. 


#5: Corydalis Yanhusuo Tuber Extract May Promote Digestion
Several Traditional Chinese Medicine formulas use Corydalis Yanhusuo Tuber Extract for digestive function, including occasional stomach pain, reflux, and other common digestive complaints.

Research suggests Corydalis Yanhusuo Tuber Extract may promote digestion via its: 
*Effects on the liver, which is responsible for the production of bile and key digestive enzymes
*Positive effects on normal digestive inflammatory response
*Positive impact on the microbiome, which preliminary studies suggest may benefit from *Berberine-rich herbs 

More research is needed. 
However, these studies lend credibility to the traditional practice of taking bitter herbs, known as “bitters” or “aperitifs,” like Dandelion, Corydalis Yanhusuo Tuber Extract, Black Radish, etc., to promote healthy digestion. 


#6: Corydalis Yanhusuo Tuber Extract May Support Various Aspects of Cognitive Function
Nootropic herbs like Ginkgo, Lion’s Mane, and Saffron are well-known for supporting cognitive function.

However, several studies suggest Corydalis Yanhusuo Tuber Extract may also promote cognitive function, particularly related to memory and learning capacity, neuron function, and Berberine’s neuroprotective benefits, but more research is needed.
Although more research is needed, this is consistent with Corydalis Yanhusuo Tuber Extract's traditional use to protect and promote brain health.



ORIGIN / HABITAT OF CORYDALIS YANHUSUO TUBER EXTRACT:
Corydalis is thought to be native to areas such as China and Japan. 
The plant can survive in harsh climates including snow and freezing temperatures. 
It is commonly found in woodlands.



CHEMICAL CONSTITUENTS OF CORYDALIS YANHUSUO TUBER EXTRACT:
Alkaloids including cordalines, tetrahydropalmatine (THP) and protapine.



HOW DOES CORYDALIS YANHUSUO TUBER EXTRACT WORK?
There isn't enough information to know how Corydalis Yanhusuo Tuber Extract might work.



PHYSICAL and CHEMICAL PROPERTIES of CORYDALIS YANHUSUO TUBER EXTRACT:
Appearance: Powder
Mesh size: 80-120
Odor: Typical odor
Weight loss: ≤ 5%
Ash content: ≤ 5%
Heavy metals: ≤ 20ppm
Pesticide residues: None
Total bacteria: ≤ 1000cfu/gm
Escherichia coli: not detected

Salmonella: not detected
Yeast: ≤ 50cfu/g
Appearance: Brown powder
Solubility: Soluble in water and alcohol
pH: Typically between 5.0 and 7.0
Density: Varies by preparation
Molecular Weight: Varies by active compounds
Extraction Method: Usually extracted through alcohol or water methods



FIRST AID MEASURES of CORYDALIS YANHUSUO TUBER EXTRACT:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of CORYDALIS YANHUSUO TUBER EXTRACT:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.



FIRE FIGHTING MEASURES of CORYDALIS YANHUSUO TUBER EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of CORYDALIS YANHUSUO TUBER EXTRACT:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of CORYDALIS YANHUSUO TUBER EXTRACT:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.



STABILITY and REACTIVITY of CORYDALIS YANHUSUO TUBER EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

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