Calcium glycinate is a chelated form of calcium that is easily absorbed by the body, making it a preferred choice for dietary supplements due to its high bioavailability and minimal gastrointestinal side effects.

Calcium glycinate supports healthy bones and teeth, helps regulate blood pressure and muscle contractions, and may be beneficial for people with celiac disease.

Calcium glycinate is used in fortified foods and beverages to enhance calcium content, making it particularly important for individuals who may have difficulty obtaining sufficient calcium from their diet alone.

CAS Number: 35947-07-0

Chemical Formula: C4H8N2O4Ca•H2O

Molecular Weight: 188.2 g/mol

Synonyms: Calcium glycinate, 35947-07-0, calcium bisglycinate, Calcium glycinate (1:2), calcium;2-aminoacetate, Glycine, Calcium Salt (2:1), 33242-26-1, 56960-17-9, 567R60Z85R, Glycine Calcium Salt (2:1), Calcium 2-aminoacetate, UNII-567R60Z85R, CalClum Glycinate, calcium aminoacetate, EINECS 251-422-9, EINECS 252-809-5, CALCIUM CHELAZOME, CALCIUM TASTE FREE, BIS(GLYCINATO)CALCIUM, SCHEMBL344659, CALCIUM, BIS(GLYCINATO)-, DTXSID30954885, OFNJDDJDXNMTHZ-UHFFFAOYSA-L, CALCIUM AMINOACETATE [WHO-DD], AKOS015918298, NS00089797, A823056, Q27261382

Calcium glycinate, Calcium and vitamin D supplementation support the maintenance of bone mass and integrity via increasing bone mineral density.

Calcium glycinate is boron plays a role in mineral metabolism and appears to support hyper-absorption of calcium.

Calcium glycinate, vitamin K helps in the maintenance of bones.

Calcium glycinate supports healthy bones and teeth and helps reduce the risk of osteoporosis

Calcium glycinate is a chelated form of calcium that is easily absorbed by the body.

Calcium glycinate is often used in health care products, such as dietary supplements and nutritional solutions.

Calcium glycinate is used to prevent or treat calcium deficiency, which can lead to conditions such as osteoporosis.

Calcium glycinate also helps regulate blood pressure and muscle contractions, and may be beneficial for people with celiac disease.

Calcium glycinate has been shown to have antimicrobial properties against bacteria, fungi, and yeast.

Calcium glycinate is a chelated form of calcium that is created by combining calcium with glycine, an amino acid.

Calcium glycinate is often used as a dietary supplement due to its high bioavailability, which means Calcium glycinate is more readily absorbed and utilized by the body compared to other forms of calcium supplements.

Calcium glycinate is known for its gentle nature on the stomach and its minimal gastrointestinal side effects, making it a preferred choice for individuals with sensitive digestive systems.

Calcium glycinate plays a crucial role in maintaining healthy bones and teeth, supporting muscle function, and contributing to overall cardiovascular health.

The chelation process, where calcium is bound to glycine, enhances Calcium glycinate's stability and solubility, allowing for effective absorption in the intestines.

Calcium glycinate is also used in various pharmaceutical formulations and nutritional products due to its efficacy and safety profile.

Calcium glycinate's use extends beyond dietary supplements to include applications in fortified foods and beverages, ensuring that individuals receive adequate calcium intake for optimal health.

Calcium glycinate is a chelated form of calcium that is easily absorbed by the body.

Calcium glycinate is often used in health care products, such as dietary supplements and nutritional solutions.

Calcium glycinate is used to prevent or treat calcium deficiency, which can lead to conditions such as osteoporosis.

Calcium glycinate also helps regulate blood pressure and muscle contractions, and may be beneficial for people with celiac disease.

Calcium glycinate has been shown to have antimicrobial properties against bacteria, fungi, and yeast.

Calcium glycinate is a chemical compound that consists of calcium bound to the amino acid glycine.

Calcium glycinate is a specialized formulation designed to enhance plant growth and development by providing a readily available source of calcium, an essential micronutrient.

With the unique combination of calcium and glycine, this fertilizer offers improved nutrient uptake and utilization, promoting healthier and more robust plants.

Uses of Calcium Glycinate:

Calcium glycinate can be used for food, medicine, health care products and other industries.

Calcium glycinate can be strengthened in dairy products (milk powder, milk, soy milk, etc.), solid drinks, cereal health products, salt and other food.

Calcium glycinate is a non-essential amino acid for human development.

Calcium glycinate is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Calcium glycinate is primarily used as a dietary supplement to support bone health and maintain adequate calcium levels in the body.

Calcium glycinate's high bioavailability makes it an effective option for individuals looking to prevent or treat calcium deficiency, support muscle function, and contribute to cardiovascular health.

Calcium glycinate is often recommended for those who experience gastrointestinal discomfort with other forms of calcium supplements due to Calcium glycinate's gentle effect on the digestive system.

Additionally, Calcium glycinate is utilized in fortified foods and beverages to enhance calcium content and support overall nutritional intake.

Calcium glycinate's stability and solubility make it a valuable ingredient in pharmaceutical formulations and nutritional products aimed at improving calcium absorption and promoting overall health.

Calcium glycinate is utilized in various contexts due to its beneficial properties and high bioavailability.

Calcium glycinate's primary uses include:

Dietary Supplements:

Calcium glycinate is widely used in dietary supplements to provide an easily absorbed form of calcium.

This helps individuals meet their daily calcium needs, which is essential for maintaining bone density, supporting muscle function, and promoting overall cardiovascular health.

Fortified Foods and Beverages:

Calcium glycinate is often added to fortified foods and beverages to enhance their nutritional value.

This is particularly important in products aimed at populations who may have difficulty obtaining sufficient calcium from their diet alone, such as the elderly or those with dietary restrictions.

Pharmaceutical Formulations:

In the pharmaceutical industry, Calcium glycinate is included in various formulations to ensure the effective delivery of calcium.

Calcium glycinate is used in tablets, capsules, and other dosage forms designed to address calcium deficiencies or support bone health.

Nutritional Products for Special Populations:

Calcium glycinate is used in nutritional products tailored for specific groups, such as pregnant women, athletes, or individuals with osteoporosis.

The gentle nature of Calcium glycinate on the digestive system makes it suitable for those who may experience gastrointestinal discomfort with other forms of calcium.

Medical Food Products:

Calcium glycinate is used in medical foods designed for individuals with specific health conditions that require controlled calcium intake.

Calcium glycinate's high absorption rate and minimal side effects make it a valuable ingredient in these specialized products.

Applications of Calcium Glycinate:

Calcium glycinate Powder is a new calcium supplement and calcium nutrition enhancer.

Calcium glycinate is formed by calcium and glycine chelate.

Calcium glycinate will be better absorbed than calcium citrate and calcium citrate-malate.

Widely used in food, beverage, dairy products, nutrient solutions, etc.

Calcium glycinate is also popularly utilized in the pharmaceutical industry.

Calcium glycinate Powder will help intensify milk goods(milk powder, milk, soymilk, etc.), solid drinks, corn health protection, salt, and other foods.

Feature of Calcium Glycinate:

Calcium glycinate is a new type of nutritional calcium supplement with stable chemical structure, good water solubility, high absorption rate of chelated structural substances.

Calcium glycinate is ring structured chelate which composes of calcium and glycine. Glycine is the smallest molecular weight amino acid, thus supplementing the same amount of calcium, with the least amount of Calcium glycinate compared to other amino acid chelated calcium.

Calcium glycinate's surface absorption rate is 6% greater than calcium lactate.

The significant difference between Calcium glycinate and inorganic/organic calcium salt is the cyclic structure of calcium and glycine chelate, with non-existence of Ca2+.

Thus Calcium glycinate greatly reduces antagonistic effect of elements such as Ca, Mg, Cu, Fe, Zn, Mn and other divalent ions in the digestive tract.

Calcium glycinate also reduces the depletion of physic acid, oxalic acid and other substances when combined with Calcium glycinate which will not cause the body stone disease and greatly improve body’s utilization of calcium.

Benefits of Calcium glycinate:

Prevents fruit and flower dropping

Reduces biotic & abiotic stress

Improves fruit storage capacity and fruit size

Calcium sustains the consistency of the cell wall, ensuring the fruit’s form and lustre

Improves fruit and floral shelf life

Increases the flowering process and improves flower setting

Advantages of Calcium Glycinate:

Calcium glycinate is a new generation product advanced in society.

Calcium glycinate is a calcium-nutrition intensifying agent with biochemical functions specific to amino acids.

Calcium glycinate is easily absorbed and utilized by the body after calcium binding and has the dual function of nutrition and treatment.

Calcium glycinate has a steady chemical structure, good water solubility, specific absorption are high, and development prospects widely.

Role of Calcium glycinate:

Calcium is used as calcium pectinate to form the middle lamella in the cell wall for the metabolism of lipids.

Involved in the enlargement and division of the cell.

Helps in the translocation of carbohydrates and also activates enzyme action in plants.

Calcium Deficiency:

Growing tips of roots and leaves turn brown and die

Buds and blossoms fall prematurely

Younger leaves may be cupped and crinkled

Chlorotic and necrotic spots

Blossom end rot disease

Preparation of Calcium Glycinate:

Many of them use the aqueous system synthesis method of Calcium glycinate.

Calcium glycinate or microwave solid source synthesis is prepared.

Calcium glycinate aqueous system synthesis method is prepared.

Calcium glycinate has shortcomings such as long reaction time, high cost, use of a large amount of acid solution or alkali caustic by-product abundance, waste liquor contamination, complex process; There are easy coke by-products, and can not easily realize the problem of technical scale-up production in microwave solid source synthesis.

A preparation method of Calcium glycinate is shown as follows:

Glycine and inorganic calcium are taken as raw materials and dispersed in absolute ethyl alcohol; a supersonic cleaner is used to apply ultrasonic reaction to a reaction system, and the reaction time is 4 to 6 hours; A reaction product is washed with an organic solvent multiple times, centrifugal filtration is carried out, vacuum drying is carried out at 60 ° C, and high purity target product is obtained.

Action Mode of Calcium Glycinate:

Calcium glycinate acts on plants by enhancing calcium uptake and utilization, strengthening cell walls, activating enzymes, facilitating nutrient transport, and regulating plant hormones.

Calcium glycinate improves calcium availability in the soil, allowing plants to efficiently absorb this essential nutrient through their roots.

Once inside the plant, Calcium glycinate is incorporated into the cell walls, providing structural strength and rigidity.

Calcium glycinate activates enzymes necessary for growth and metabolic processes, ensuring optimal biochemical reactions.

By facilitating nutrient transport, Calcium glycinate aids in the distribution of other vital elements throughout the plant.

Additionally, Calcium glycinate helps regulate plant hormones, influencing various growth and developmental processes.

Overall, these actions promote robust plant growth, increased stress tolerance, improved fruit quality, and overall plant vigour.

Chemical Properties of Calcium Glycinate:

Calcium glycinate is slightly soluble in water and ether.

Calcium glycinate is highly hygroscopic.

Calcium glycinate Powder Raw Material, API should be kept in tightly closed containers to avoid the heat source.

Dosage of Calcium Glycinate:

Modulation of milk powder: 3000mg/kg-7200mg/kg

Ice cream: 2400mg/kg-3000mg/kg

Rice, wheat flour and its products: 1600mg/kg-3200mg/kg

Soy flour, soy milk powder: 1600mg/kg-8000mg/kg

Beverages: 160mg/kg-1350 mg/kg

Western-style pastries, biscuits: 2670mg/kg-5330 mg/kg

Fermented milk: 250 mg/kg-1000mg/kg

Handling and Storage of Calcium Glycinate:

Handling:

Use appropriate personal protective equipment (PPE) to avoid direct contact.

Handle with clean, dry tools to prevent contamination.

Avoid generating dust.

Storage:

Store in a cool, dry place, away from moisture and direct sunlight.

Keep containers tightly closed when not in use.

Ensure proper labeling and separation from incompatible substances.

Stability and Reactivity of Calcium Glycinate:

Stability:

Calcium glycinate is stable under normal conditions of use and storage.

Calcium glycinate does not decompose easily and is resistant to typical environmental conditions.

Reactivity:

Generally non-reactive and does not pose significant hazards.

Avoid contact with strong acids or bases as they may affect stability.

Does not react violently or release hazardous gases.

First Aid Measures of Calcium Glycinate:

Inhalation:

If inhaled, move the person to an area with fresh air.

Seek medical advice if symptoms persist.

Ingestion:

If a large amount is ingested, seek medical attention immediately.

Typically, Calcium glycinate is considered safe when used as directed.

Skin Contact:

Rinse affected area with plenty of water.

If irritation develops, seek medical advice.

Eye Contact:

Rinse eyes with water for at least 15 minutes.

Seek medical attention if irritation persists.

Firefighting Measures of Calcium Glycinate:

Fire Hazard:

Calcium glycinate is not flammable and does not pose a significant fire hazard.

Extinguishing Media:

Use extinguishing media suitable for the surrounding fire.

Calcium glycinate itself does not require specific firefighting measures.

Accidental Release Measures of Calcium Glycinate:

Containment:

Isolate the area and prevent further release if possible.

Use appropriate containment materials to prevent spread.

Cleanup:

Sweep up the material carefully and place Calcium glycinate in suitable, labeled containers for disposal.

Avoid creating dust during cleanup.

Clean the area with water to remove any residual material.

Exposure Controls/Personal Protective Equipment of Calcium Glycinate:

Exposure Limits:

No specific exposure limits are established for Calcium glycinate.

Protective Equipment:

Respiratory Protection:

Not typically required under normal conditions.

Use if dust is generated.

Hand Protection:

Use gloves to prevent skin contact.

Eye Protection:

Safety glasses or goggles are recommended if there is a risk of splashes or dust.

Skin Protection:

Use protective clothing as needed to avoid prolonged skin contact.

Identifiers of Calcium Glycinate:

CAS Number: 35947-07-0

REACH Pre-Reg: 252-809-5

FDA UNII: 567R60Z85R

MDL: MFCD00671334

Molecular Weight: 115.14525000

Formula: C2 H5 Ca N O2

CAS No: [35947-07-0]

MDL No: MFCD00671334

Chemical Formula: C4H8N2O4Ca•H2O

Molecular Weight: 188.2 g/mol

Smiles: C(C(=O)[O-])N.C(C(=O)[O-])N.[Ca+2]

CAS No.: 35947-07-0

Chemical Name: Calcium glycinate

CBNumber: CB4511861

Molecular Formula: C2H7CaNO2

Molecular Weight: 117.16

Stereochemistry: ACHIRAL

Molecular Formula: 2C2H4NO2.Ca

Molecular Weight: 188.195

Optical Activity: NONE

Properties of Calcium Glycinate:

Molecular Formula: C2H7CaNO2

Molar Mass: 117.16

Density: 1629[at 20℃]

Boling Point: 240.9°C at 760 mmHg

Flash Point: 99.5°C

Water Solubility: 580.12g/L at 20℃

Vapor Presure: 0Pa at 20℃

Density: 1629[at 20℃]

vapor pressure: 0Pa at 20℃

Water Solubility: 580.12g/L at 20℃

InChI: InChI=1S/C2H5NO2.Ca.2H/c3-1-2(4)5;;;/h1,3H2,(H,4,5);;;

InChIKey: VAVSHKSPXHOHMF-UHFFFAOYSA-N

SMILES: C(=O)(O)CN.[Ca]

LogP: -3.65 at 20℃

FDA UNII: 567R60Z85R

Molecular Weight: 188.20 g/mol

Hydrogen Bond Donor Count: 2

Hydrogen Bond Acceptor Count: 6

Rotatable Bond Count: 0

Exact Mass: 188.0109976 g/mol

Monoisotopic Mass: 188.0109976 g/mol

Topological Polar Surface Area: 132Ų

Heavy Atom Count: 11

Complexity: 37.4

Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0

Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes

Assay: 98.00 to 100.00

Food Chemicals Codex Listed: No

Boiling Point: 240.90 °C. @ 760.00 mm Hg (est)

Vapor Pressure: 0.012300 mmHg @ 25.00 °C. (est)

Flash Point: 211.00 °F. TCC ( 99.50 °C. ) (est)

logP (o/w): -1.027 (est)