OLEIC ACID DIETHANOLAMIDE (OLEAMIDE DEA)
Oleic acid diethanolamide (Oleamide DEA) is a fatty acid derivative of diethanolamine (DEA) as a viscous liquid or waxy solid.
Oleic acid diethanolamide (Oleamide DEA), also known as 9-Octadecenamide, is used industrially as a lubricant, a slip agent, and a corrosion inhibitor.
Oleic acid diethanolamide (Oleamide DEA) is a mixture of ethanolamides of oleic acid.
CAS Number: 93-83-4
EC Number: 700-972-2
Molecular Formula: C22H43NO3
Molecular Weight: 369.58
Synonyms: alkamide AJ58BN, chimipal OLD, clindrol 2000, comperlan OD, crillon ODE, emulsifier WHC, foamid 0-20, hetamide OC, N,N-bis(2-hydroxyethyl) oleamide, N,N-bis(2-hydroxyethyl)-(Z)-9-octadecenamide, (9E)-N,N-bis(2-hydroxyethyl)-9-octadecenamide, (E)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, lauerel SD-400, lauridit OD, mackamide O, marlamid D 1885, ninol 201, 9-octadecenamide, N,N-bis(2-hydroxyethyl)-, (9E)-, oleic diethanol amide, oleic diethanolamide, oleyl diethanol amide, oleyl diethanolamide, schercomid ODA, schercomide SO-A, stafoam DO, steinamid DO 280SE, witcamide 511C, OLEIC DIETHANOLAMIDE, Oleic acid diethanolamide, 93-83-4, N,N-Diethanololeamide, Oleic acid diethanolamide (Oleamide DEA), Amisol ode, Diethanololeamide, Mackamide O, Comperlan OD, Emulsifier WHC, Schercomid ODA, Alrosol O, Lauridit OD, Nitrene NO, Stafoam DO, N,N-Bis(2-hydroxyethyl)oleamide, Witcamide 511C, Marlamid D 1885, Steinamid DO 280SE, (Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (Z)-, EMID 6545, Oleic acid diethanolamine condensate, Oleamide, N,N-bis(2-hydroxyethyl)-, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9Z)-, DTXSID8026563, n,n-bis-(2-hydroxyethyl)oleamide, 5C1I3E441Q, N,N-Bis(2-hydroxyethyl)-9-octadecenamide, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, Clindrol 2000, Clindrol 2020, UNII-5C1I3E441Q, Incromide OD, Mackamide MO, Amidex O, Varamide A-7, EINECS 202-281-7, oleoyl diethanolamide, Alkamide DO-280, OLEYLAMIDE DEA, BRN 1985420, CALAMIDE O, Norfox F-221, PROTAMIDE OFO-LD, Oleic acid diethanolamine, Rewomid DO 280 SE, Ninol 90201, (Z)-N,N-Bis(2-hydroxyethyl)-9-octadecenamide, Oleic acid diethanolamide (Oleamide DEA) [INCI], CHEMBL15712, Schercomid SO-A (Salt/Mix), Diethanolamine oleic acid amide, DTXCID606563, SCHEMBL1614760, N,N-diethanololeamide, AldrichCPR, ZINC8585892, Tox21_202528, CAS-93-83-4, NCGC00091445-01, NCGC00260077-01, (9Z)-N,N-Bis(2-hydroxyethyl)-9-octadecenamide #, Q27261806, Oleic acid diethanolamide, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, Diethanolamine oleic acid amide, N,N-Bis(2-hydroxyethyl)-9-octadecenamide, Oleic acid diethanolamide (Oleamide DEA), Oleic diethanolamide, (Z)-N,N-Bis(2-hydroxyethyl)-9-octadecenamide, Alrosol O, Amisol ode, BRN 1985420, Clindrol 2000, Clindrol 2020, Comperlan OD, Diethanololeamide, EMID 6545, Emulsifier WHC, Lauridit OD, Mackamide O, Marlamid D 1885, N,N-Diethanololeamide, Nitrene NO, Oleamide, N,N-bis(2-hydroxyethyl)-, Schercomid ODA, Stafoam DO, Steinamid DO 280SE, UNII-5C1I3E441Q, Witcamide 511C, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9Z)-, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (Z)-, Oleic acid diethanolamine condensate, (9Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, (9E)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, Oleic acid diethanolamide, (9E)-N,N-Bis(2-hydroxyethyl)-9-octadecenamid [German] [ACD/IUPAC Name], (9E)-N,N-Bis(2-hydroxyethyl)-9-octadecenamide [ACD/IUPAC Name], (9E)-N,N-Bis(2-hydroxyéthyl)-9-octadécénamide [French] [ACD/IUPAC Name], 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9E)- [ACD/Index Name], Oleic acid diethanolamine, (E)-N,N-bis(2-hydroxyethyl)octadec-9-enamide, (Z)-N,N-Bis(2-hydroxyethyl)-9-octadecenamide, 39390-56-2 [RN], 5299-69-4 [RN], 73380-02-6 [RN], 8036-36-0 [RN], 95917-64-9 [RN], 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (Z)-, Alrosol O, Amisol ode, Clindrol 2000, Clindrol 2020, Comperlan OD, Emulsifier WHC, Lauridit OD, Mackamide O, Marlamid D 1885, N,N-Bis(2-hydroxyethyl)-9-octadecenamide, N,N-BIS(2-HYDROXYETHYL)OCTADEC-9-ENAMIDE, N,N-Bis(2-hydroxyethyl)oleamide, N,N-Diethanololeamide, Nitrene NO, Oleic acid diethanolamide (Oleamide DEA), Oleamide, N,N-bis(2-hydroxyethyl)-, Oleic diethanolamide, Oleyl diethanolamide, Schercomid ODA, Stafoam DO, Steinamid DO 280SE, Witcamide 511C
Oleic acid diethanolamide (Oleamide DEA) is a derivative of oleic acid and diethanolamine (DEA).
Oleic acid diethanolamide (Oleamide DEA) belongs to the group of so-called alkanolamides and is produced mainly from coconut oil.
Oleic acid diethanolamide (Oleamide DEA) is in the form of a viscous amber liquid or in the form of a solid wax.
Oleic acid diethanolamide (Oleamide DEA) is soluble in water and oil.
Oleic acid diethanolamide (Oleamide DEA) is used in cosmetics as an emulsifier, antistatic agent, forms the gel structure of the product, maintains balanced moisture and viscosity, improves the glide and spreadability of the product.
Oleic acid diethanolamide (Oleamide DEA) is added to personal hygiene products, shampoos, styling products, hair dyes, lotions and bath foams.
Oleic acid diethanolamide (Oleamide DEA) is considered a not completely safe substance for human health.
Oleic acid diethanolamide (Oleamide DEA) should not be taken orally.
Oleic acid diethanolamide (Oleamide DEA) can irritate the skin, dry it out and worsen the manifestations of dermatitis or other skin diseases.
Oleic acid diethanolamide (Oleamide DEA) is listed as potentially carcinogenic because alkanolamides can release carcinogenic nitrosamides.
Oleic acid diethanolamide (Oleamide DEA) is a derivative of oleic acid and diethanolamine.
Oleic acid diethanolamide (Oleamide DEA) is a surfactant derived from the fatty acids of coconut oil.
Oleic acid diethanolamide (Oleamide DEA) is mainly used in the production of shampoos, where it increases their foaming ability and the stability of the foam.
Oleic acid diethanolamide (Oleamide DEA) also acts as an emulsifier, increasing the water content of the product.
Oleic acid diethanolamide (Oleamide DEA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.
Oleic acid diethanolamide (Oleamide DEA) is used at industrial sites and in manufacturing.
Oleic acid diethanolamide (Oleamide DEA) changes its density to a more pliable one, forming a gel structure of the product.
Oleic acid diethanolamide (Oleamide DEA) is also used in fabric softeners, for example.
Oleic acid diethanolamide (Oleamide DEA) is not considered a safe substance.
Oleic acid diethanolamide (Oleamide DEA) may contain nitrosamines, which are carcinogenic.
Oleic acid diethanolamide (Oleamide DEA) may cause mild skin irritation and redness in some people.
Oleic acid diethanolamide (Oleamide DEA) is a nonionic surfactant commonly used as a detergency booster, anticorrosive and skin-protective agent in industrial degreasing and cleaning agents, such as engine cleaners.
Furthermore, Oleic acid diethanolamide (Oleamide DEA) serves as an agent providing for enhanced scourability and rinsability of water-free oils and hydraulic fluids.
Oleic acid diethanolamide (Oleamide DEA) can also form a component of aqueous emulsions for metal cutting and non-corrosive working fluids.
Oleic acid diethanolamide (Oleamide DEA) is also an ingredient in fabric conditioners and personal care products such as shampoos, conditioners or water-free soaps.
Oleic acid diethanolamide (Oleamide DEA)'s antistatic, anticorrosive and emulsifying properties are made use of in coatings, rubber and oil industries as well as emulsion polymerization.
INCI system (International Nomenclature of Cosmetic Ingredients) is a nomenclature of cosmetic ingredients existing in accordance with the law of the European Union.
The system defines the order in which the names of the ingredients are listed, starting with the substance used in the highest amount, and ending with the substance of the lowest concentration.
Oleic acid diethanolamide (Oleamide DEA) is the name used in this system for oleic acid diethanolamide, a non-ionic surfactant.
Oleic acid diethanolamide (Oleamide DEA) in the name refers to the product of amide-diethanolamine conversion.
Ungraded products are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Oleic acid diethanolamide (Oleamide DEA) is an excellent water-in-oil emulsifier, pigment dispersant and a good viscosity builder.
Oleic acid diethanolamide (Oleamide DEA) is used as an effective dispersant for mineral clays or pigments and as an emulsifier for all types of aromatic and aliphatic hydrocarbon solvents, oil additives, polymer materials antistatic agents, anti-friction agents, boiler cleaning rust dispersant and fiber processing lubricants.
Cocamide DEA, Lauramide DEA, Linoleic acid diethanolamide (Oleamide DEA) and Oleic acid diethanolamide are viscous liquids or waxy solids.
These ingredients are fatty acids derivatives of diethanolamine (DEA).
In cosmetics and personal care products, these ingredients are used in the formulation of shampoos, hair dyes, bath products, and lotions.
Cocamide DEA, Lauramide DEA, Linoleic acid diethanolamide (Oleamide DEA), and Oleic acid diethanolamide increase foaming capacity and/or stabilize foam.
Oleic acid diethanolamide (Oleamide DEA) is also used to thicken the aqueous (water) portion of cosmetics and personal care products.
Oleic acid diethanolamide (Oleamide DEA), also known as 9-Octadecenamide, is used industrially as a lubricant, a slip agent, and a corrosion inhibitor.
Ungraded products are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Oleic acid diethanolamide (Oleamide DEA) is produced by a condensation reaction at a 1:1 or 1:2 molar ratio of a mixture of oleic acid to diethanolamine.
Oleic acid diethanolamide (Oleamide DEA) contains 6.0-7.5% free fatty acids (as oleic acid).
Oleic acid diethanolamide (Oleamide DEA) is an organic compound with the formula CH3(CH2)7CH=CH(CH2)7CONH2.
Oleic acid diethanolamide (Oleamide DEA) is the amide derived from the fatty acid oleic acid.
Oleic acid diethanolamide (Oleamide DEA) is a colorless waxy solid and occurs in nature.
Sometimes labeled as a fatty acid primary amide (FAPA), Oleic acid diethanolamide (Oleamide DEA) is biosynthesized from N-oleoylglycine.
Oleic acid diethanolamide (Oleamide DEA) is supplied as a clear, dark amber liquid.
Oleic acid diethanolamide (Oleamide DEA) is suitable for high slip formulas for metal working applications.
Applications of Oleic Acid Diethanolamide (Oleamide DEA):
Oleic acid diethanolamide (Oleamide DEA) is nonionic surfactants impart excellent viscosity enhancing and foam stabilization in anionic based systems like hand washing liquids, shampoos, body cleansers and other personal care products.
They act as lubricant agent, thickening agent and wetting agent.
Their very good emulsifying property also provides applications in the field of pharmaceuticals, agricultural preparations, and textile processing; rust inhibiting, latex stabilizing, anti-static function in textiles, dye-leveling, waterproofing and water-in-oil additives as well as very good emulsifying.
Oleic acid diethanolamide (Oleamide DEA) is manufactured by condensation of mono- or diethanolamine and the methylester of long chain fatty acids, whereby the monoethanolamides are further ethoxylated.
Nonionic surfactant that imparts excellent viscosity enhancing and foam stabilization in anionic based systems like hand washing liquids, shampoos, body cleansers and other personal care products.
Oleic acid diethanolamide (Oleamide DEA) acts as a lubricant agent, thickening agent and wetting agent.
Oleic acid diethanolamide (Oleamide DEA) has very good emulsifying properties for pharmaceuticals, agricultural preparations, and textile processing; rust inhibiting, latex stabilizing, anti-static function in textiles, dye-leveling, waterproofing and water-in-oil additives as well as very good emulsifying properties.
Oleic acid diethanolamide (Oleamide DEA) is use as cleansing agent.
Oleic acid diethanolamide (Oleamide DEA) is use as emulsifying agent, dispersing agent.
Oleic acid diethanolamide (Oleamide DEA) is use as solubilizing agent.
Oleic acid diethanolamide (Oleamide DEA) is use as foam stabilizing agent.
Oleic acid diethanolamide (Oleamide DEA) is use as antirust agent, anticorrosive agent.
Oleic acid diethanolamide (Oleamide DEA) is use as thickening agent.
Applications in cosmetic products:
In cosmetics, Oleic acid diethanolamide (Oleamide DEA), Rapamide DEA has several functions.
Oleic acid diethanolamide (Oleamide DEA) is an excellent viscosity regulator, antistatic and foaming agent.
The use of this alkanolamide in the composition of shampoos reduces the tendency of hair to pick up statics, Oleic acid diethanolamide (Oleamide DEA) easily binds to the negatively charged surface of the hair.
The use of Oleic acid diethanolamide (Oleamide DEA), Rapamide DEA in all kinds of soaps, liquids and gels improves the quality and stability of the resulting foam in contact with anionic substances.
Commonly, Oleic acid diethanolamide (Oleamide DEA) is considered a factor that perfectly nourishes and conditions the hair.
Thus, the addition of this agent to shampoos facilitates combing and makes the hair shine.
Due to its concentrating properties, Oleic acid diethanolamide (Oleamide DEA) is also used in moisturising creams and colouring preparations.
Oleic acid diethanolamide (Oleamide DEA) (ODEA) or N,N-Dietolazolamide can be used as a degreasing agent, anti-wrinkle agent and anti-clothing agent, which are widely used in industrial cleaning, household washing, chemical fibers of textiles, leather and personal care products, etc.
Application areas:
Dyes and pigments
HI&I cleaning
Emulsion polymerization
Metalworking
Paints coatings
Personal care
Industrial auxiliaries
Construction chemicals
Oil fields
Uses of Oleic Acid Diethanolamide (Oleamide DEA):
Oleic acid diethanolamide (Oleamide DEA) is applied in household products such as detergent with its excellent detergency and emulsified power.
Oleic acid diethanolamide (Oleamide DEA) can also used as in metal working fluids with its excellent lubricity, emulsified power and compatibility with other ingredients.
Besides the use in cosmetics, Oleic acid diethanolamide (Oleamide DEA) also has technical applications.
Oleic acid diethanolamide (Oleamide DEA)'s properties allow the compound to be used in metalworking products, textiles, detergents, processing fluids, degreasing preparations.
Oleic acid diethanolamide (Oleamide DEA) serves as an agent that improves washability and rinsing of water-free oils, which improves the effectiveness of products.
Oleic acid diethanolamide (Oleamide DEA) can also be used as a component of aqueous emulsions for non-corrosive working fluids.
Oleic acid diethanolamide (Oleamide DEA) is also used in the preparation of products acting as metalworking coolants and polishing agents.
The antistatic, anticorrosive and emulsifying properties of Oleic acid diethanolamide (Oleamide DEA) are used in the rubber industry and in emulsion polymerization.
As a concentrating component, Oleic acid diethanolamide (Oleamide DEA) is also used in paints.
Usual quality >70 % in diethanolamides.
Oleic acid diethanolamide (Oleamide DEA) is obtained by reaction of oleic acid with an excess of diethanolamine.
Oleic acid diethanolamide (Oleamide DEA) is classified as nonionic surfactant.
Oleic acid diethanolamide (Oleamide DEA) is an amber liquid at room temperature.
Commercial uses:
Shampoos
Fabric softener
Technical uses:
Cutting fluids,
Degreasers,
Hard surface cleaners,
Dilutable,
Hard surface cleaners,
Metalworking cleaners,
Textile
Industry Uses:
Fuels and fuel additives,
Lubricants and lubricant additives,
Processing aids, not otherwise listed,
Surface active agents.
Consumer Uses:
Cleaning and furnishing care products,
Fuels and related products,
Laundry and dishwashing products,
Lubricants and greases,
Non-TSCA use,
Personal care products.
Cosmetic uses:
Antistatic,
Surfactant-foam boosting,
Viscosity controlling.
Other Uses:
Shampoos
Hair Dyes
Bath Products
Lotions
Foam Stabilizer
Functions of Oleic Acid Diethanolamide (Oleamide DEA):
Oleic acid diethanolamide (Oleamide DEA) is a kind of widely used oil-soluble surfactant with good emulsification, anti-static, anti-atomization, anti-friction, excellent diffusion and rust resistance;
Oleic acid diethanolamide (Oleamide DEA) can be used as a lubricant, antirust and antiwear agent.
Oleic acid diethanolamide (Oleamide DEA) is widely used in the metal processing industry.
Oleic acid diethanolamide (Oleamide DEA) can be added to mineral oil to improve the dispersion effect of various synthetic fats in the oil;
Oleic acid diethanolamide (Oleamide DEA) has some effect against rust.
Oleic acid diethanolamide (Oleamide DEA) can be used to combine corrosion inhibitors to improve the dispersion effect of other corrosion inhibitors in oil and metal surfaces;
Oleic acid diethanolamide (Oleamide DEA) is widely used in industrial cleaning, household washing, chemical fiber textiles, leather and personal care products.
Oleic acid diethanolamide (Oleamide DEA) is a transparent yellow liquid, water-soluble amide with excellent viscosity response and foaming properties.
Oleic acid diethanolamide (Oleamide DEA) is commonly used in various personal care and industrial applications.
General characteristics of Oleic Acid Diethanolamide (Oleamide DEA):
From the chemical perspective, amides are products of the transformation of carbonic acids (mainly fatty acids) or other acids with compounds containing nitrogen in their structure (e.g. alkyl amines, amino acids).
Oleic acid diethanolamide (Oleamide DEA) is mainly a synthetic substance.
From a chemical point of view, Oleic acid diethanolamide (Oleamide DEA) is a product of a reaction between oleic acid (C18H34O2) with an excess of diethanolamine (NH(CH2CH2OH)2).
The reaction product is an amber liquid at room temperature.
Oleic acid diethanolamide (Oleamide DEA) is moderately lipophilic and slightly soluble in water.
Oleic acid diethanolamide (Oleamide DEA) is very stable under normal conditions.
The CAS number of Oleic acid diethanolamide (Oleamide DEA) is 68603-38-3.
Oleic acid diethanolamide (Oleamide DEA) is an unambiguous numerical term assigned to a chemical substance by a US organization, the Chemical Abstracts Service (CAS).
Oleic acid diethanolamide (Oleamide DEA) is biodegradable.
Biochemical and medical aspects of Oleic Acid Diethanolamide (Oleamide DEA):
In terms of natural occurrence, oleamide was first detected in human plasma.
Oleic acid diethanolamide (Oleamide DEA) was later shown to accumulate in the cerebrospinal fluid during sleep deprivation and induces sleep in animals.
Oleic acid diethanolamide (Oleamide DEA) has been considered as a potential treatment for mood and sleep disorders, as well as cannabinoid-regulated depression.
In terms of its sleep inducing effects, Oleic acid diethanolamide (Oleamide DEA) is speculated that oleamide interacts with multiple neurotransmitter systems.
Some in-vitro studies show that cis-oleamide is an agnoist for the cannabinoid receptor CB-1 with an affinity around 8 micromolar.
However, given oleamide's relatively low affinity for CB-1 and uncertainty about the concentration and biological role of oleamide in-vivo, Oleic acid diethanolamide (Oleamide DEA) has been argued that it is premature to classify oleamide as an endocannabinoid.
At larger doses oleamide can lower the body temperature of mice by about 2 degrees, with the effect lasting about two hours.
The mechanism for this remains unknown.
Oleic acid diethanolamide (Oleamide DEA) is rapidly metabolized by fatty acid amide hydrolase (FAAH), the same enzyme that metabolizes anandamide.
Oleic acid diethanolamide (Oleamide DEA) has been postulated that some effects of oleamide are caused by increased concentrations of anandamide brought about through the inhibition of FAAH.
Occurrence of Oleic Acid Diethanolamide (Oleamide DEA):
Synthetic oleamide has a variety of industrial uses including as a slip agent, a lubricant, and a corrosion inhibitor.
Oleamide was found to be leaching out of polypropylene plastics in laboratory experiments, affecting experimental results.
Since polypropylene is used in a wide number of food containers such as those for yogurt, the problem is being studied.
Oleamide is "one of the most frequent non-cannabinoid ingredients associated with Spice products."
Analysis of 44 products synthetic cannabinoid revealed oleamide in 7 of the products tested.
Synthesis of Oleic Acid Diethanolamide (Oleamide DEA):
Oleic acid diethanolamide (Oleamide DEA) was prepared by stirring equimolar quantities of oleic acid and diethanolamine in a nitrogen atmosphere while heating to 182° C. and maintaining the temperature for 2 hours while removing water.
Oleic acid diethanolamide (Oleamide DEA), which also contained a significant amount of ester, was representative of another commercial amide.
General Manufacturing Information of Oleic Acid Diethanolamide (Oleamide DEA):
Industry Processing Sectors:
All other basic organic chemical manufacturing,
All other chemical product and preparation manufacturing,
Fabricated metal product manufacturing,
Oil and gas drilling, extraction, and support activities,
Petroleum lubricating oil and grease manufacturing,
Petroleum refineries,
Soap, cleaning compound, and toilet preparation manufacturing,
Textiles, apparel, and leather manufacturing.
Handling and Storage of Oleic Acid Diethanolamide (Oleamide DEA):
Handling:
Use in a well-ventilated area to avoid inhalation of vapors.
Avoid contact with skin and eyes. Use appropriate personal protective equipment (PPE) such as gloves and safety goggles.
Keep containers tightly closed when not in use.
Avoid eating, drinking, or smoking in areas where Oleic acid diethanolamide (Oleamide DEA) is used or stored.
Storage:
Keep Oleic acid diethanolamide (Oleamide DEA) containers tightly closed in a dry, cool and well-ventilated place.
Store Oleic acid diethanolamide (Oleamide DEA) at room temperature in the original container.
Store Oleic acid diethanolamide (Oleamide DEA) away from incompatible materials.
Store in a cool, dry place, away from direct sunlight and sources of ignition.
Keep containers tightly sealed and away from incompatible materials.
Ensure storage area is well-ventilated.
Stability and Reactivity of Oleic Acid Diethanolamide (Oleamide DEA):
Stability:
Oleic acid diethanolamide (Oleamide DEA) is stable under normal conditions of use and storage.
Avoid exposure to high temperatures and direct sunlight to maintain stability.
Reactivity:
May react with strong oxidizing agents.
Decomposes at elevated temperatures, releasing potentially hazardous fumes.
Not reactive with water, but can form emulsions.
Safety of Oleic Acid Diethanolamide (Oleamide DEA):
Safety of cosmetics containing:
Oleic acid diethanolamide (Oleamide DEA) is an ingredient that is approved for use in cosmetics in limited concentrations.
The chemical law stipulates that a compound is on the list of substances allowed for use in cosmetics only in a limited amount, scope and conditions of use.
The safety of Oleic acid diethanolamide (Oleamide DEA) was assessed by CIR experts.
Alkanolamide itself does not irritate the eyes and may cause mild skin irritation, but does not cause severe allergic reactions.
At the moment, there are no studies confirming the adverse environment impact.
All the criteria and restrictions for the use of a given substance are contained in the relevant legal documents regarding the production of cosmetics.
Oleic acid diethanolamide (Oleamide DEA) is a chemical compound alkylamide, diethanolamide, a mixture of ethanolamines and oleic acid.
DEA (diethanolamine) is a water-soluble molecule obtained by the reaction of ethylene oxide with ammonia.
Oleic acid diethanolamide (Oleamide DEA) shows reactive capacity is an aminoalcohol as it combines the properties of alcohols and amines.
First Aid Measures of Oleic Acid Diethanolamide (Oleamide DEA):
Inhalation:
Move the affected person to fresh air immediately.
Seek medical attention if symptoms persist.
Skin Contact:
Wash affected area with plenty of water and soap.
Remove contaminated clothing.
Seek medical attention if irritation occurs.
Eye Contact:
Rinse eyes immediately with plenty of water for at least 15 minutes.
Remove contact lenses if present and easy to do.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek medical attention immediately.
Firefighting Measures of Oleic Acid Diethanolamide (Oleamide DEA):
Fire Fighting:
Use appropriate extinguishing agents such as foam, dry chemical, or carbon dioxide (CO2).
Water spray can be used to cool containers and reduce the risk of fire spread.
Wear self-contained breathing apparatus (SCBA) and protective clothing when fighting fires involving Oleic acid diethanolamide (Oleamide DEA).
Fire and Explosion Hazards:
Oleic acid diethanolamide (Oleamide DEA) is not highly flammable but can burn if exposed to high temperatures or flames.
Combustion may produce harmful fumes such as oxides of carbon.
Accidental Release Measures of Oleic Acid Diethanolamide (Oleamide DEA):
Personal Precautions:
Wear appropriate PPE, including gloves, goggles, and a respirator if needed.
Evacuate non-essential personnel from the area.
Environmental Precautions:
Prevent the material from entering drains, waterways, or soil.
Spill Cleanup:
Absorb the spill with inert materials like sand or vermiculite.
Collect the absorbed material and place Oleic acid diethanolamide (Oleamide DEA) in a suitable waste container.
Clean the area with water and soap.
Ensure proper disposal of waste in accordance with local regulations.
Exposure Controls/Personal Protective Equipment of Oleic Acid Diethanolamide (Oleamide DEA):
Exposure Limits:
No specific occupational exposure limits established for Oleic acid diethanolamide (Oleamide DEA).
Engineering Controls:
Ensure adequate ventilation to minimize airborne concentrations.
Use local exhaust ventilation if necessary.
Personal Protective Equipment:
Skin Protection:
Wear chemical-resistant gloves and protective clothing.
Eye Protection:
Use safety goggles or face shields to protect against splashes.
Respiratory Protection:
Use a suitable respirator if ventilation is insufficient or if there is a risk of inhalation.
Hygiene Practices:
Wash hands and face thoroughly after handling.
Remove contaminated clothing and wash before reuse.
Identifiers of Oleic Acid Diethanolamide (Oleamide DEA):
Chemical description: Oleic fatty acid diethanolamide produced via the 2:1 reaction
INCI name: Oleamide DEA
IUPAC name: Amides, C18-unsatd., N,N-bis(hydroxyethyl)
CAS #: 93-83-4
EC #: 700-972-2
CAS Number: 93-83-4
Chem/IUPAC Name: N,N-bis(2-Hydroxyethyl)-(Z)-9-octadecenamide
EINECS/ELINCS No: 202-281-7
COSING REF No: 35649
CAS No.: 5299-69-4
Chemical Name: Oleic acid diethanolamide
Synonyms: 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-
CBNumber: CB0965903
Molecular Formula: C22H43NO3
Molecular Weight: 369.58
Properties of Oleic Acid Diethanolamide (Oleamide DEA):
appearance at 20°C: amber viscous liquid
density at 20°C, g/cm3: 0.97
dry matter, % wt., min.: 90.0
pH, 1% aqueous solution: 8.0 - 11.0
IUPAC/Chemical Name: N,N-bis(2-hydroxyethyl)oleamide
InChi Key: LPMBTLLQQJBUOO-KTKRTIGZSA-N
InChi Code: InChI=1S/C22H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)23(18-20-24)19-21-25/h9-10,24-25H,2-8,11-21H2,1H3/b10-9-
SMILES Code: CCCCCCCC/C=C\CCCCCCCC(N(CCO)CCO)=O
Appearance: Solid powder
Chemical Properties of Oleic acid diethanolamide (Oleamide DEA):
Appearance: Yellow transparent viscous liquid
Boiling Point: 150°C
CAS Number: 93-83-4
Density: 0.96 g/cm3
EINECS Number: 202-281-7
InChI: 1S/C22H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)23(18-20-24)19-21-25/h9-10,24-25H,2-8,11-21H2,1H3/b10-9-
InChIKey: LPMBTLLQQJBUOO-KTKRTIGZSA-N
Melting Point: -18°C
Molar Mass: 369.59 g/mol
Molecular Formula: C22H43NO3
NFPA 704: H-1,F-1,R-0,C-NA
Synonyms: 9-Octadecenamide,N,N-bis(2-hydroxyethyl)-, (9Z)-;9-Octadecenamide,N,N-bis(2-hydroxyethyl)-, (Z)-;Oleamide, N,N-bis(2-hydroxyethyl)-;Diethanololeamide;Oleic acid diethanolamide (Oleamide DEA);Oleic Acid Diethanolamide;Oleic Diethanolamide;N,N-bis(2-hydroxyethyl)oleamide
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Molecular Weight: 369.6
XLogP3-AA: 5.8
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 19
Exact Mass: 369.32429423
Monoisotopic Mass: 369.32429423
Topological Polar Surface Area: 60.8 Ų
Heavy Atom Count: 26
Complexity: 325
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Density: 1.0±0.1 g/cm3
Boiling Point: 525.6±45.0 °C at 760 mmHg
Molecular Formula: C22H43NO3
Molecular Weight: 369.582
Flash Point: 271.7±28.7 °C
Exact Mass: 369.324280
LogP: 6.61
Vapour Pressure: 0.0±3.1 mmHg at 25°C
Index of Refraction: 1.488
Names of Oleic Acid Diethanolamide (Oleamide DEA):
Regulatory process names:
N,N-bis(2-hydroxyethyl)oleamide
N,N-bis(2-hydroxyethyl)oleamide
IUPAC names:
(9Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide
(E)-N,N-bis(2-hydroxyethyl)octadec-9-enamide
(Z)-N,N-BIS(2-HYDROXYETHYL)-9-OCTADECENAMIDE
(Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide
9-Octadecenamide, N,N-bis(2-hydroxyethyl)-,
9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9Z)-
N,N-bis(2-hydroxyethyl)-(Z)-9-octadecenamide
N,N-bis(2-hydroxyethyl)octadec-9-enamide
N,N-Bis(2-hydroxyethyl)oleamide
N,N-bis(2-hydroxyethyl)oleamide
N,N-Bis(2-idrossietil)oleammide
N,N-Diethanololeamide
Oleic acid diethanolamide (Oleamide DEA)
Preferred IUPAC name:
(9Z)-Octadec-9-enamide
Trade name:
Alfonal OL
Other names:
oleoyl-amide
Oleylamide
9-Octadecenamide
(Z)-9-Octadecenamide
9,10-Octadecenoamide
Oleic acid amide
Cis-9,10-octadecenoamide
Other identifier:
93-83-4
