CAS NO: 126-30-7
METATAGS;2,2-dimethyl-1,3-propanediol;Neopentyl glycol;2,2-Dimethylpropane-1,3-diol;126-30-7;2,2-DIMETHYL-1,3-PROPANEDIOL;Dimethylolpropane;Neopentylene glycol;Neopentanediol;Neopentylglycol;Neol;1,3-Propanediol, 2,2-dimethyl-;Hydroxypivalyl alcohol;Dimethyltrimethylene glycol;2,2-Dimethyltrimethylene glycol;UNII-QI80HXD6S5;NPG Glycol;NSC 55836;2,2-Dimethyl-1,3 propanediol;EINECS 204-781-0;Propanediol, 2,2-dimethyl-, 1,3-;BRN 0605291;AI3-05739;2,3 propanediol;SLCVBVWXLSEKPL-UHFFFAOYSA-N;SBB056814;DSSTox_CID_7036;DSSTox_RID_78285;DSSTox_GSID_27036;WLN: Q1X1 & 1 & 1Q;CAS-126-30-7;2,2-dimethylolpropane;AC1L1LFZ;AC1Q1NLU;ACMC-1C2GC;QI80HXD6S5;SCHEMBL19621;CBDivE_004836;4-01-00-02551 (Beilstein Handbook Reference);KSC177Q9P;2,2-Bis(hydroxymethyl)propane;2,2-dimethyl-1,3-propandiol;2,2-dimethylpropan-1,3-diol;2,2-dimethyl 1,3-propanediol;2.2-dimethyl-1,3-propanediol;2,3-Dimethyl-1,3-propanediol;CHEMBL3184801;DTXSID8027036;CTK0H7897;2,2-dimethyl -1,3-propanediol;2,2-dimethyl-1,3-propane diol;2,2-dimethyl-propane-1,3-diol;NSC6366;MolPort-003-932-306;ZINC388175;NSC-6366;NSC55836;1,3-Dihydroxy-2,2-dimethylpropane;2,2-Dihydroxy-2,2-dimethylpropane;2,2-Dimethyl-1,3-dihydroxypropane;Tox21_201363;Tox21_303298;ANW-18922;MFCD00004685;NSC-55836;ZINC00388175;AKOS005068060;MCULE-3663555151;NE10344;RL01297;RTR-003853;TRA0083916;2,2-Dimethyl-1,3-propanediol, 99%;NCGC00249034-01;NCGC00256980-01;NCGC00258915-01;AJ-20472;AK109182;AN-22975;CJ-03141;I936;KB-16396;OR012210;OR112803;SC-79890;ZB011337;LS-120360;ST2415601;TR-003853;D0791;FT-0653714;ST50982294;31682-EP2295399A2;31682-EP2308858A1;31682-EP2311816A1;31682-EP2311817A1;55473-EP2270101A1;55473-EP2284165A1;55473-EP2292597A1;55473-EP2301919A1;55473-EP2301924A1;55473-EP2308865A1;55473-EP2374895A1;218793-EP2371805A1;218793-EP2374787A1;I14-2699;J-506805;F0001-0385;Z1235963404;InChI=1/C5H12O2/c1-5(2,3-6)4-7/h6-7H,3-4H2,1-2H;111109-35-4;1,3-Propanediol, 2,2-dimethyl- [ACD/Index Name];2,2-Dimethyl-1,3-propandiol [German] [ACD/IUPAC Name];2,2-Dimethyl-1,3-propanediol [ACD/IUPAC Name];2,2-Diméthyl-1,3-propanediol [French] [ACD/IUPAC Name];2,2-dimethylpropane-1,3-diol;Neopentyl glycol [Wiki];1,3-Dihydroxy-2,2-dimethylpropane;126-30-7 [RN];2,2-Dimethyl-1,3 propanediol,2,2-Dimethyl-1,3-dihydroxypropane;2,2-Dimethyl-1,3-Propanediol (en);2,2-Dimethyltrimethylene glycol;2,3-Dimethyl-1,3-propanediol;204-781-0 [EINECS];2-ethylpropane-1,3-diol;4-01-00-02551 (Beilstein Handbook Reference) [Beilstein];DIMETHYLTRIMETHYLENE GLYCOL;Hydroxypivalyl alcohol;MFCD00004685 [MDL number];Neol;Neopentanediol;Neopentylene glycol;Neopentylglycol;NPG;NPG Glycol;propane-1,3-diol, 2,2-dimethyl-;Propanediol, 2,2-dimethyl-, 1,3-;Q1X1 & 1 & 1Q [WLN];UNII:QI80HXD6S5;UNII-QI80HXD6S5;Neopentyl glycol mixed steartates and myristates;Neopentyl glycol ester of myristic and stearic acids;Octadecanoic acid,mixed esters with myristic acid and neopentyl glycol;1,3-Propanediol, 2,2-dimethyl;Neol;NEOL(R);NPG Glycol;Neopentanediol;NEOPENTYL GLYCO;NEOPENTYL GLYCOL;Dimethylolpropane;NEOPENTYLENE GLYCOL;hydroxypivalylalcohol;NEOPENTYL GLYCOL pure;2-METHOXY-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE Unsaturated polyester resin 5-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CHLORO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE Ibuprofen 3-METHOXY-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-(TRIFLUOROMETHYL)-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CYANO-5-BROMOPHENYLBORONIC ACID PINACOL ESTER Sodium formate 2-BROMO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE ISOQUINOLINE-4-BORONIC ACID 2,2-DIMETHYLPROPANEDIOL-1,3 CYCLIC ESTER Triethylene glycol dimethacrylate 4-CHLORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE;Diethylene glycol Trimethylol propane Dimethyl fumarate Dimethyl sulfate N,N-Dimethylformamide 1-Methoxy-2-propanol PROPYLENE GLYCOL 1,3-Propanediol Bis(neopentyl glycolato)diboron Poly(propylene glycol) 1,4-Butanediol 2-Methyl-2,4-pentanediol Dimethyl disulfide Ethylene glycol diacetate Ethylene glycol Propylene glycol 2-METHYL-1,3-PROPANEDIOL 1-Phenoxy-2-propanol;1,3-Dihydroxy-2,2-dimethylpropane 1,3-propanediol,2,2-dimethyl- 2,2-Dimethyl-1,3-dihydroxypropane 2,2-dimethyl-3-propanediol 2,2-Dimethylpropane-1,3-diol 2,2-dimethyltrimethyleneglycol 3-Propanediol,2,2-dimethyl-1 Dimethylolpropane Hydroxypivalyl alcohol hydroxypivalylalcohol Neol Neopentanediol NPG Glycol DIMETHYLTRIMETHYLENE GLYCOL Building Blocks 126-30-7 2,2-BIS(HYDROXYMETHYL)PROPANE 2,2-DIHYDROXY-2,2-DIMETHYLPROPANE 2,2-DIMETHYL-1,3-PROPANEDIOL NEOPENTYLENE GLYCOL NEOPENTYL GLYCOL NEOL(R) Polyols Oxygen Compounds Organic Building Blocks NEOPENTYL GLYCO 2,2-DIMETHYL-1,3-PROPANEDIOL (NPG) 2,2-Dimethyl-1,3 propandiol CH32CCH2OH2 2,2-dimethyl-1,3-propanediol (Neopentyl Glycol) Intermediates of Dyes and Pigments 2,2-Dimethylpropan-1,3-diol 126307 Organics 2,2-DIMETHYL-1,3-PROPANEDIOL 99.5+% HOCD2CCD32CD2OH NEOPENTYL GLYCOL pure Neopentylglycol, NPG Glycol 2,2-Dimethyl-1,3-propanediol,99% 2,2-Dimethyl-1,3-propanediol,97% neopentyl glycol(2,2-dimethyl-1,3-propanedil) 2,2-Dimethyl-1,3-propanediol,NPG Glycol, Neopentylglycol Neopentyl Glycol (Slurry and Flake) 2,2-DiMethyl-1,3-propanediol, 99% 25GR 2,2-DiMethyl-1,3-propanediol, 99% 500GR 2,2-Bis(hydroxymethyl)propane 2,2-Dihydroxy-2,2-dimethylpropane Neopentyl Glycol 2,2-DIMETHYL-1,3-PROPANEDIOL FOR SYNTHES Neopentyl glycol (NPG) 2,2-DiMethyl-1,3-propanediol 99% 2,2-DiMethyl-1,3-propanediol, 99.5%, 99.5% Neopentylglycol flakes Pyridines 2,2-Dimethyl-1,3-propanediol(NPG Glycol);Neopentyl glycol;2,2-Bis(hydroxymethyl)propane;2,2-Dihydroxy-2,2-dimethylpropane;Neopentyl Glycol;2,2-dimethyl propane-1,3-diol;dimethyl trimethylene glycol;2,2-dimethyl-1,3-propane diol;2,2-dimethyl-1,3-propanediol;dimethylol propane;2,2-dimethylpropane-1,3-diol;dimethyltrimethylene glycol;hydroxypivalyl alcohol;NPG glycol;neopentane diol;neopentylene glycol;neopentylglycol;propane-1,3-diol, 2,2-dimethyl-;1,3-propanediol, 2,2-dimethyl-;Neopentyl glycol; 2,2-dimethylpropane-1,3-diol; 2-ethylpropane-1,3-diol;2,2-Dimethyl-1,3-propanediol; Neoppentylglycol; 1,3-Dihydroxy-2,2-dimethylpropane; 2,2-Bis(hydroxymethyl)propane; 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethyl-1,3-propanediol; 2,2-Dimethyl-1,3-propylene Glycol; 2,2-Dimethylolpropane; 2,2-Dimethylpropan-1,3-diol; 2,2-Dimethylpropanediol Monoacrylate Monomethacrylate; 2,2-Dimethyltrimethylene Glycol; Dimethylolpropane; Hydroxypivalyl Acohol; NSC 55836; NSC 6366; Neopentanediol; Neopentyl Glycol; Neopentylene Glycol; Nexcoat 600;NPG Glycol; Neopentylglycol;Neopentylene glycol; 1,3-Propanediol, 2,2-dimethyl-; 2,2-Dimethyl-1,3-propanediol;Neopentil glikol nedir,neopentil glikol nerede kullanılır,nerelerde kullanılır,neopentil glikol kullanımı,neopentil glikol hangi alanlarda kullanılır,neopentil glikol kimyasal özellikleri,fiziksel özellikleri,neopentil hangi alanlarda kullanılır,neopentil glikol teknik özellikleri,neopentil glikol kimyasal formülü,neopentil glikol speskti,spesifikasyonu,güvenlik bilgi formu,neopentil glikol teknik şartnamesi;NEOPENTYL GLYCOL;2,2-DIMETHYL-1,3-DIHYDROXYPROPANE;2,2-DIMETHYL-1,3-PROPANEDIOL;1,3-PROPANEDIOL, 2,2-DIMETHYL-;DIMETHYLOLPROPANE;2,2-DIMETHYLTRIMETHYLENE GLYCOL;2,2-BIS(HYDROXYMETHYL)PROPANE;2,2-Dimethyl-1,3-propanediol may be used in the synthesis of:;2,2-dimethyl-1,3-propanediol cyclic phosphorochloridate[1];2,2-dimethyl-1,3-propanediol cyclic phenylphosphonate[1];[1',3'-(2',2'-dimethylpropylene)]-2-iodo-3-octyl-5-thienylboronate[2];cyclic carbonate[3];2,2-dimethyl-1,3-propanediol bis(cyclic-2,2-dimethyltrimethylene phosphite);1,3-Benzodioxole, 2,2-dimethyl- [ACD/Index Name];2,2-Dimethyl-1,3-benzodioxol [German] [ACD/IUPAC Name];2,2-Dimethyl-1,3-benzodioxole [ACD/IUPAC Name];2,2-Diméthyl-1,3-benzodioxole [French] [ACD/IUPAC Name];[14005-14-2];1,2-(Isopropylidenedioxy)benzene;14005-14-2 [RN];2,2-DIMETHYL-1,3-BENZODIOXAZOLE;2,2-dimethyl-2H-1,3-benzodioxole;2,2-Dimethylbenzo[d][1,3]dioxole;2,2-dimethylbenzo[d]1,3-dioxolane;MFCD08061594 [MDL number];NEOPENTIL GLIKOL;NEOPENTILGLIKOL;NEOPENTİL GLİKOL;NEOPENTİLGLİKOL;NEO PENTIL GLIKOL;NEO PENTİL GLİKOL;NEO PENTIL GLYCOL;NEOPENTILGLYCOL;NEO PENTIL GILIKOL;NEOPENTIL GILIKOL;NEOPENTILGILIKOL;NEO PENTİL GİLİKOL;NEOPENTİLGİLİKOL;neopentıl glıkol;neopentılglıkol;neopentil glikol;neopentilglikol;neo pentil glikol;neo pentıl glıkol;neo perntıl glycol;neopentılglycol;neopentılglıkol;neopentıl gılıkol;neopentılgılıkol;neopentyl glycol;neo pentyl glycol;neopentylglycol;NEOPENTYL GLYCOL;NEO PENTYL GLYCOL;NEOPENTYLGLYCOL;2,2-dimetilpropan_1,3_diol;2,2-Dimethyl-1,3-propanediol;2,2-Dimethylpropane-1,3-diol;1,3-Dihydroxy-2,2-dimethylpropane
EC NUMBER: 204-781-0
Molecular Formula of Neopentyl Glycol
C5H12O2
IUPAC Name of Neopentyl Glycol
2,2-dimethylpropane-1,3-diol
Experimental Properties of Neopentyl Glycol
Physical Description of Neopentyl Glycol
2,2-DIMETHYLPROPANE-1,3-DIOL is a white crystalline solid. Melting point 130°C.
Liquid
Liquid, PelletsLargeCrystals
OtherSolid
OtherSolid, PelletsLargeCrystals, WetSolid
PelletsLargeCrystals
Boiling Point of Neopentyl Glycol
406.4° F at 760 mm Hg
Melting Point of Neopentyl Glycol
260.6° F
Flash Point of Neopentyl Glycol
225° F
Density v
1.1 g/cm³
Chemical Properties of Neopentyl Glycol
white solid
Uses of Neopentyl Glycol
NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator.
General Description of Neopentyl Glycol
White crystalline solid.
Air & Water Reactions
Soluble in water.
Reactivity Profile of Neopentyl Glycol
2,2-Dimethyl-1,3-propanediol may generate toxic gases in combination of with alkali metals, nitrides, and strong reducing agents. Reacts with inorganic acids and carboxylic acids to form esters plus water. Converted to aldehydes or acids by oxidizing agents. May initiate the polymerization of isocyanates and epoxides.
2,2-Dimethyl-1,3-propanediol readily absorbs moisture on exposure to air.
Used for protection of carbonyl groups as 4,4-dimethyl-1,3-dioxanes, often preferred to the more usual 1,3-dioxolanes due to easier separation and greater stability, for protection of carbonyl group of 4-bromo-2-propanone using p-toluenesulfonic acid in the presence of triethyl orthoformate. It is used in the synthesis of polyesters, paints, lubricants, and plasticizers.
Especially used in paint and coating resin production, gelcoat and powder coating. A very limited amount is converted into esters and used in aircraft engine oil production.
Polyol synthesized by the reaction of isobutyraldehyde with formaldehyde. It is a raw material for polyester resins.
Neopentyl glycol (IUPAC name: 2,2-dimethylpropane-1,3-diol) is an organic chemical compound. It is used in the synthesis of polyesters, paints, lubricants, and plasticizers.
When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water.
By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced.
Other names: 1,3-Propanediol, 2,2-dimethyl-; Dimethylolpropane; Neopentanediol; Neopentylene glycol; 2,2-Dimethyl-1,3-propanediol; Dimethyltrimethylene glycol; Hydroxypivalyl alcohol; NPG; Neol; 1,3-Dihydroxy-2,2-dimethylpropane; 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethylpropane-1,3-diol; NPG Glycol; 2,2-Dimethyltrimethylene glycol; NSC 55836
Synonyms: 1,3-Propanediol, 2,2-dimethyl-; 2,2-Dimethyl-1,3-propanediol; 2,2-Dimethyltrimethylene glycol; Dimethylolpropane; Dimethyltrimethylene glycol; Hydroxypivalyl alcohol; Neol; Neopentanediol; Neopentylene glycol; NPG; 2,2-Dimethylpropane-1,3-diol; Propanediol, 2,2-dimethyl-, 1,3-; [ChemIDplus] Dimethylol propane; [CAMEO] 1,3-Dihydroxy-2,2-dimethylpropane; [ICSC] 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethylolpropan; 2,2-Dimetil-1,3-propandiolo; Dimetilolpropano; Neopentilene glicole; Neopentilglicole; Neopentylglycol; Neopentylglykol; Pentaglycol; [IUCLID]
Category
Alcohols and Polyols, Other
Description
Colorless to white hygroscopic solid; [ICSC] White hygroscopic crystals with a mild odor;
Sources/Uses
Used to make plasticizers and polyesters and as modifier of alkyd resins; Used in chemical synthesis and in the polymers industry; [IUCLID] Used to make large scale and fine chemicals, rubber products, plastic products, textiles, leather, fur, wood and wood products, pulp-paper and paper products, non-metallic mineral products (i.e. plasters and cement), in printing and reproduction of recorded media, building and construction work, scientific research and development, and consumer construction chemicals; [ECHA REACH Registrations]
Key Applications
Polyester coatings; gel coatings; synthetic marble; polyurethane coatings; synthetic lubricants
Product Description
This functional glycol can be used as an intermediate for both plasticizers and for synthetic lubricants. In most polyester resin formulations, it is used as the sole glycol component. It offers excellent thermal stability, weathering, and stain resistance.
Uses
Neopentyl glycol (NPG) is used primarily in base resins for coatings. Important uses are also found in hydraulic fluids, synthetic lubricant oils, greases, metal-working fluids and aircraft engine lubricants. Other outlets include textiles, pharmaceuticals, pesticides, plasticisers and petroleum. NPG is shipped as flake, molten and slurry.
Main Applications: Alkyd resin paint, polyester resin, powdered paint
Neopentyl glycol, also known as Dimethylolpropan, is a colorless-to-white, hygroscopic crystalline, organic chemical compound that is used in the synthesis of paints, polyesters, lubricants, and plasticizers. The combustible, slightly toxic compound can be harmful if ingested or is absorbed through skin contact. It is known to cause skin and eye irritation.
The chemical formula for Neopentyl glycol is C5H12O2. Its CAS is 126-30-7. The crystalline substance is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde, which creates the intermediate hydroxypivaldehyde. This can be converted to Neopentyl glycol with either excess formaldehyde or catalytic hydrogenation of the aldehyde group to an alcohol group.
Neopentyl glycol is soluble in water, benzene, chloroform, and very soluble in ethanol and diethyl ether.
The industrial uses for the combustible organic compound include dyes, functional fluids in closed systems, intermediates, lubricants and lubricant additives, paint and coating additives, and processing aids specific to petroleum production.
Consumer uses include adhesives and sealants, paints and coatings, and paper products.
Supply/demand
Global capacity stood at 485,000 tonnes/year in 2005, with 173,000 tonnes/year in western Europe, 140,000 tonnes/year in the US, 134,000 tonnes/year in Asia-Pacific (excluding Japan) and 38,000 tonnes/year in Japan, according to consultancy TranTech.
Western Europe is the largest consumer at about 118,000 tonnes/year, followed by the US at 108,000 tonnes/year and Asia-Pacific at 94,000 tonnes/year. Japan, Latin America and the Middle East consume 25,700 tonnes/year, 10,500 tonnes/year and 9,250 tonnes/year, respectively. Western Europe and the US are the world's biggest exporters at 31,000 tonnes/year and 16,300 tonnes/year, respectively. Asia-Pacific was a net importer in 2005 by 5,500 tonnes.
Neopentyl glycol is an organic chemical synthesized by aldol reaction of formaldehyde and isobutyraldehyde. It is majorly used in the synthesis of plasticizers, paints, lubricants and polyester resins. The product has wide applications in several industries including construction, aerospace, automotive, paints and coatings, consumer products and electronic applications. The significant growth in market as a result of enhanced properties of the product will create new avenues for the manufacturers in forecasted time frame. Overall growth in construction industry, increasing demand for consumer goods and automotive in the emerging economies will boost the neopentyl glycol market expansion.
Technology
There are two main routes to NPG using isobutyraldehyde and formaldehyde. In one, the raw materials react with a strongly alkaline catalyst to form NPG. But, large amounts of formate salts are formed as byproduct and the process is only economically viable when a profitable use is found for the formate.
In a second and more common process, the aldolisation reaction is carried out in the presence of an amine catalyst. This is further hydrogenated in the presence of a catalyst and the molten NPG is solidified by means of a flaking roll, or a crystallising or cooling belt.
Health and safety
NPG is a white, crystalline solid with a mint-like odour. Finely dispersed particles form explosive mixtures in air and it reacts violently with oxidants.
Formula: C5H12O2 / (CH3)2C(CH2OH)2
Molecular mass: 104.2
Boiling point: 210°C
Melting point: 127°C
Density: 1.1 g/cm³
Solubility in water, g/100ml at 20°C: 83
Vapour pressure, Pa at 20°C: 30
Relative vapour density (air = 1): 3.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0
Flash point: 107°C
Auto-ignition temperature: 388°C
Explosive limits, vol% in air: 1.1-11.4
Octanol/water partition coefficient as log Pow: -0.84
Physical State; Appearance
COLOURLESS-TO-WHITE HYGROSCOPIC CRYSTALS.
Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.
Chemical dangers
Reacts violently with oxidants.
1,3-Propanediol, 2,2-dimethyl- [ACD/Index Name]
126-30-7 [RN]
2,2-Dimethyl-1,3-propandiol [German] [ACD/IUPAC Name]
2,2-Dimethyl-1,3-propanediol [ACD/IUPAC Name]
2,2-Diméthyl-1,3-propanediol [French] [ACD/IUPAC Name]
2,2-dimethylpropane-1,3-diol
204-781-0 [EINECS]
4-01-00-02551 [Beilstein]
MFCD00004685 [MDL number]
Neopentanediol
Neopentyl glycol [Wiki]
Neopentylene glycol
Neopentylglycol
NPG Glycol
Propanediol, 2,2-dimethyl-, 1,3-
QI80HXD6S5
TY5775000
UNII-QI80HXD6S5
1,3-Dihydroxy-2,2-dimethylpropane
2, 2-Dimethyl-1, 3-propanediol
2,2-dimethylpropane-1,3-diol
2,2-Dimethyl-1,3 propanediol
2,2-Dimethyl-1,3-dihydroxypropane
2,2-Dimethyltrimethylene glycol
2,3-Dimethyl-1,3-propanediol
2-ethylpropane-1,3-diol
Dimethyltrimethylene glycol
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:143768
Hydroxypivalyl alcohol
Neol
NPG
propane-1,3-diol, 2,2-dimethyl-
Q1X1 & 1 & 1Q [WLN]
Preferred IUPAC name
2,2-Dimethylpropane-1,3-diol
2,2-Dimethyl-1,3-propanediol
CAS Number: 126-30-7
Reactions
Neopentyl glycol is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde.
This creates the intermediate hydroxypivaldehyde, which can be converted to neopentyl glycol with either excess formaldehyde or by palladium on carbon hydrogenation.
It is used as a protecting group for ketones, for example in gestodene synthesis.
A condensation reaction of neopentyl glycol with 2,6-di-tert-butylphenol gives CGP-7930.
Organoboronic acid esters of neopentyl glycol are useful in the Suzuki reaction
It has been reported that plastic crystals of neopentyl glycol exhibit a colossal barocaloric effect (CBCEs), which is a cooling effect caused by pressure-induced phase transitions.
The obtained entropy changes are about 389 joules per kilogram per kelvin near room temperature.
This CBCE phenomenon is likely to be very useful in future solid-state refrigeration technologies.
Chemical formula: C5H12O2
Molar mass:104.148 g/mol
Melting point: 129.13 °C (264.43 °F; 402.28 K)
Boiling point: 208 °C (406 °F; 481 K)
Solubility in water:good
Solubility: soluble in benzene, chloroform, very soluble in ethanol, diethyl ether
1,3-Propanediol, 2,2-dimethyl-
2,2-Dimethyl-1,3-propanediol
2,2-dimethyl-1,3-propanediol
2,2-dimethylpropane-1,3-diol
EC Inventory
2,2-dimethylpropane-1,3-diol
2,2-Dimethyltrimethylene glycol
Dimethylolpropane
Dimethyltrimethylene glycol
Hydroxypivalyl alcohol
Neol
Neopentanediol
Neopentyl glycol
Neopentylene glycol
NPG
CAS names
1,3-Propanediol, 2,2-dimethyl-
Other
IUPAC names
1,3-Propanediol, 2,2-dimethyl-
2,2-Dimethyl-1,3-propanediol
2,2-dimethyl-1,3-Propanediol
2,2-dimethyl-1,3-propanediol
2,2-dimethylpropan-1,3-diol
C&L Inventory
2,2-Dimethylpropane-1,3-diol, Other
2,2-dimethylpropane-1,3-diol, Other
2,2-dimethylpropane-1,3-diol, Other
2,2-dimethylpropane-1,3-diol (neopentyl glycol)
NEOPENTYL GLYCOL
Neopentyl Glycol
Neopentyl glycol
NEOPENTYL GLYCOL
Neopentyl glycol
Neopentyl Glycol (NPG)
Neopentylglycol
propylene glycol
Trade names
1,3-Dihydroxy-2,2-dimethylpropane
1,3-Propanediol, 2,2-dimethyl- (6CI, 7CI, 8CI, 9CI)
2,2-Dimethyl-1,3-dihydroxypropane
2,2-Dimethyl-1,3-propanediol
2,2-Dimethyltrimethylene glycol
Dimethylolpropane
Fomrez Series
Hydroxypivalyl alcohol
Neo Pentyl glycol
Neopentanediol
Neopentil Glicole
Neopentyl glycol
Neopentylene glycol
Neopentylglykol
NPG
VIBRATHANE Series
Witcobond Series
Neopentyl glycol
126-30-7
2,2-Dimethylpropane-1,3-diol
2,2-DIMETHYL-1,3-PROPANEDIOL
Dimethylolpropane
1,3-Propanediol, 2,2-dimethyl-
Neopentanediol
Neopentylene glycol
Neopentylglycol
Neol
Hydroxypivalyl alcohol
Dimethyltrimethylene glycol
NPG Glycol
2,2-Dimethyltrimethylene glycol
UNII-QI80HXD6S5
NSC 55836
CCRIS 3273
2,2-Dimethyl-1,3 propanediol
NPG
EINECS 204-781-0
Propanediol, 2,2-dimethyl-, 1,3-
BRN 0605291
QI80HXD6S5
AI3-05739
2,3 propanediol
1,3-Dihydroxy-2,2-dimethylpropane
2,2-Dimethyl-1,3-propanediol, 99%
WLN: Q1X1 & 1 & 1Q
CAS-126-30-7
2,2-Bis(hydroxymethyl)propane
MFCD00004685
2,2-dimethylolpropane
ACMC-1C2GC
EC 204-781-0
SCHEMBL19621
CBDivE_004836
4-01-00-02551 (Beilstein Handbook Reference)
KSC177Q9P
2,2-dimethyl-1,3-propandiol
2,2-dimethylpropan-1,3-diol
2,2-dimethyl 1,3-propanediol
2.2-dimethyl-1,3-propanediol
2,3-Dimethyl-1,3-propanediol
2,2-dimethyl -1,3-propanediol
2,2-dimethyl-1,3-propane diol
2,2-dimethyl-propane-1,3-diol
2,2-Dihydroxy-2,2-dimethylpropane
2,2-Dimethyl-1,3-dihydroxypropane
Tox21_201363
1,3-Dihydroxy-2,2-dimethylpropane
1,3-Propanediol, 2,2-dimethyl- (6CI, 7CI, 8CI, 9CI)
2,2-Dimethyl-1,3-dihydroxypropane
2,2-Dimethyl-1,3-propanediol
2,2-Dimethyltrimethylene glycol
Dimethylolpropane
Fomrez Series
Hydroxypivalyl alcohol
NPG
Neo Pentyl glycol
Neopentanediol
Neopentyl glycol
Neopentylene glycol
Neopentylglykol
VIBRATHANE Series
Witcobond Series
EC NUMARASI: 204-781-0
Neopentil Glikolün Moleküler Formülü
C5H12O2
Neopentil Glikolun Adı: IUPAC
2,2-dimetilpropan-1,3-diol;
Neopentil Glikolün Deneysel Özellikleri
Neopentil Glikolün Fiziksel Tanımı
2,2-DİMETİLPROPAN-l, 3-DİOL, beyaz bir kristalimsi katıdır. Erime noktası 130 ° C.
Sıvı
Sıvı, PelletLarj Kristalleri
OtherSolid
DiğerleriHarici, PelletlerLargeCrystaller, WetSolid
PelletsLargeCrystals
Neopentil Glikol Kaynama Noktası
760 mm Hg'de 406.4 ° F
Neopentil Glikol Ergime Noktası
260.6 ° F
Neopentil Glikolün Parlama Noktası
225 ° F
Yoğunluk v
1,1 g / cm³
Neopentil Glikolün Kimyasal Özellikleri
Beyaz katı
Neopentil Glikol Kullanımı
NPG Glikol, tetrafenilporfirinlerin sentezinde kullanılır. Ayrıca bir protein kinaz modülatörü olan Bryostatin 2 sentezinde de kullanılır.
Neopentil Glikolun Genel Açıklaması
Beyaz kristal katı.
Hava ve Su Reaksiyonları
Suda çözünür.
Neopentil Glikolün Reaktivite Profili
2,2-Dimetil-l, 3-propandiol, alkali metaller, nitrürler ve kuvvetli indirgeme maddeleri ile kombinasyon halinde zehirli gazlar üretebilir. Asit ve su oluşturan inorganik asitler ve karboksilik asitlerle reaksiyona girer. Oksitleyici maddeler ile aldehitlere veya asitlere dönüştürülür. İzosiyanatların ve epoksitlerin polimerizasyonunu başlatabilir.
2,2-Dimetil-l, 3-propandiol havaya maruz kaldıkça nemi kolaylıkla emer.
4-bromo-2-karboksilik asidin karbonil grubunun korunması için karbonil gruplarının daha kolay ayrılma ve daha fazla kararlılık nedeniyle genellikle olağan 1,3-dioksolanlara tercih edilen 4,4-dimetil-1,3-dioksanlar olarak korunması için kullanılır. Propanon ile trietil ortoformat varlığında p-toluensulfonik asit kullanılarak hazırlanır. Polyester, boya, yağlayıcı ve plastikleştiricilerin sentezinde kullanılır.
Özellikle boya ve kaplama reçinesi üretimi, jelkot ve toz boyalarda kullanılır. Çok sınırlı bir miktar esterlere dönüştürülür ve uçak motor yağı üretiminde kullanılır.
İzobütiraldehidin formaldehit ile reaksiyona girmesiyle sentezlenen poliol. Polyester reçinelerin hammaddesidir.
