NMP
N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam.
N-methyl-2-pyrrolidone appears as a clear colorless liquid with a "fishlike" odor.
N-methylpyrrolidin-2-one is a member of the class of pyrrolidine-2-ones that is pyrrolidin-2-one in which the hydrogen attached to the nitrogen is replaced by a methyl group.
NMP (N-Methyl-2-Pyrrolidone) is a polar solvent with outstanding characteristics. It has a wide range of applications because it offers very high solvency, high boiling point, low freezing point, and ease of handling.
CAS: No. 872-50-4
EINECS: No. 212-828-1
N-Methyl-2-Pyrrolidone,
1-Methyl-2-Pyrrolidone,
1-Methyl-Pyrrolidine-2-one,
N-Methyl-2-Pyrrolidinone
NMP has a role as a polar aprotic solvent. It is a N-alkylpyrrolidine, a lactam and a member of pyrrolidin-2-ones.
Denser than water.
Flash point 199°F.
Contact may irritate skin, eyes and mucous membranes.
May be toxic by ingestion.
NMP is a colorless liquid, although impure samples can appear yellow.
NMP is miscible with water and with most common organic solvents.
NMP also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide.
NMP is used in the petrochemical and plastics industries as a solvent, exploiting its nonvolatility and ability to dissolve diverse materials
Preparation
NMP is produced industrially by a typical ester-to-amide conversion, by treating butyrolactone with methylamine.
Alternative routes include the partial hydrogenation of N-methylsuccinimide and the reaction of acrylonitrile with methylamine followed by hydrolysis.
About 20,000 to 30,000 tons are produced annually.
Applications
NMP is used to recover certain hydrocarbons generated in the processing of petrochemicals, such as the recovery of 1,3-butadiene and acetylene.
1-Methylpyrrolidin-2-one is used to absorb hydrogen sulfide from sour gas and hydrodesulfurization facilities.
Its good solvency properties have led to NMP's use to dissolve a wide range of polymers.
Specifically, it is used as a solvent for surface treatment of textiles, resins, and metal coated plastics or as a paint stripper.
N-Methyl-2-Pyrrolidone is also used as a solvent in the commercial preparation of polyphenylene sulfide. In the pharmaceutical industry, N-methyl-2-pyrrolidone is used in the formulation for drugs by both oral and transdermal delivery routes.
N-Methyl-2-Pyrrolidone is also used heavily in lithium ion battery fabrication, as a solvent for electrode preparation, though there is much effort to replace it with solvents of less environmental concern, like water.
Preferred IUPAC name: 1-Methylpyrrolidin-2-one
Other names:1-Methyl-2-pyrrolidone;N-Methylpyrrolidone;N-Methylpyrrolidinone;Pharmasolve; CAS Number: 872-50-4
Applications
NMP is used to produce fine chemicals from mass-produced chemicals.
NMP applications in the electronics field have expanded in recent years. NMP's high polarity and high solvency power along with our high purity, high-grade production technology enable the high performance needed in this field.
NMP can dissolve organic and inorganic compounds equally well or better than chlorofluorocarbon solvents. Therefore NMP is used in various industrial fields as a cleaning or release agent.
NMP is replacing 1,1,1-trichloroethane in metal cleaning applications due to the world-wide environmental pollution problems associated with chlorinated solvents.
1) Electronics
Wax, flux removal
Burr removal
Electronic parts cleaning
Semiconductor parts cleaning
Solvent for lithium battery manufacturing
Semiconductor photo-resist thinner
Color filter photo-resist thinner
2) Automotive
Mold cleaning
Metal (parts) cleaning
3) Chemical
Extract agent (acetylene, BTX, butadiene)
Synthetic resin surface coating solvent
Reaction solvents (PPS, polyimide, etc.)
Equipment washing
4) Optical
Plastic lens manufacturing equipment cleaning
5) Pharmaceutical and Agricultural Chemicals
Water-soluble solvent
Cleaning
Extraction
N-Methyl-2-Pyrrolidone (NMP)
Chemical synonyms: 1-Methyl-2-pyrrolidone; N-Methylpyrrolidone; N-Methylpyrrolidinone; NMP; 1-Methyl-2-pyrrolidone
Product description
N-Methyl-2-Pyrrolidone (NMP) is a high boiling, polar aprotic, low viscosity liquid. NMP has a good solvency for a wide range of organic and inorganic compounds and it is miscible with water at all temperatures and has a high chemical and thermal stability. It is used as a solvent for engineering polymers and coating resins. Additionally, the polar nature and the low surface tension of NMP makes it an excellent cleaning medium and paint stripping solvent.
NMP is a powerful solvent with a low volatility used for a wide range of chemicals and finds its application among others in:
Petrochemical processing:
NMP is used as extraction medium in several industrial processes because of its affinity for unsaturated hydrocarbons and aromatics, for example butadiene recovery, BTX extraction, lube oil purification, ...
As illustration for the strong selectivity of NMP towards acetylene, the table below shows the solubility of acetylene in various solvents.
Electronics:
NMP is used as photoresist stripper, for defluxing, degreasing and cleaning.
NMP is a solvent for the production of FCCL, polyamide/polyimide wire enamels, epoxy and polyurethane coatings, ...
Pharmaceuticals:
NMP can be used as solvent, extraction medium, …
Industrial and household cleaning:
NMP is used for paint stripping, in graffiti removers, oven cleaners, in automotive and industrial cleaner formulations, ...
Agrochemicals:
NMP can be used as solvent during synthesis or as a formulation agent.
Characteristics
NMP is a 5-member-ring compound containing nitrogen. It has a wide range of uses due to the following excellent characteristics.
N-Methylpyrrolidone is highly polar and miscible with most organic solvents (alcohols, ethers, ketones, aromatic hydrocarbons, chlorinated hydrocarbons, etc.). Organic and inorganic substances are highly soluble in it.
N-Methylpyrrolidone mixes with water in all proportions.
N-Methylpyrrolidone has a high flash point compared to similar solvents.
The boiling point is high, the freezing point is low, and handling is easy.
N-Methylpyrrolidone is chemically and thermally stable, and not corrosive.
Applications/uses
Electronics
Paints & coatings
Polymer & plastic
Process solvents
Solvents/stripping agents
Wire wrappers
1-METHYL-2-PYRROLIDINONE
872-50-4
N-Methylpyrrolidone
N-Methyl-2-pyrrolidone
1-methylpyrrolidin-2-one
Methylpyrrolidone
1-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidinone
M-Pyrol
N-Methylpyrrolidinone
1-Methylpyrrolidone
2-Pyrrolidinone, 1-methyl-
1-Methylpyrrolidinone
n-methyl-pyrrolidone
1-Methylazacyclopentan-2-one
1-Methyl-5-pyrrolidinone
N-methylpyrrolidin-2-one
NMP
N-Methyl-gamma-butyrolactam
Methyl pyrrolidone
N-methyl pyrrolidone
1-methylpyrrolidine-2-one
N-methyl pyrrolidinone
Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidon
Methylpyrrolidinone
UNII-JR9CE63FPM
2-Pyrrolidinone, methyl-
N-Methyl-alpha-pyrrolidone
N-Methylpyrrolidon
NSC 4594
Agsolex 1
N-Methyl-alpha-pyrrolidinone
CCRIS 1633
N-methyl-pyrrolidinone
Methylpyrrolidone, N-
HSDB 5022
N-Methyl-2-pyrrolidon
N-Methylpyrrolid-2-one
EINECS 212-828-1
JR9CE63FPM
2687-44-7
N-methyl-pyrrolidin-2-one
1-methyl-pyrrolidin-2-one
N-Methyl-.alpha.-pyrrolidone
CHEMBL12543
N-Methyl-.gamma.-butyrolactam
N-Methyl-.alpha.-pyrrolidinone
N-Methylpyrrolidinon
26138-58-9
51013-18-4
pharmasolve
CAS-872-50-4
Pyrrolidinone, methyl-
1-Methyl-2-pyrrolidinone, 99.5%, for HPLC
Methylpyrrolidone [NF]
1-Methyl-2-pyrrolidinone, 99.5+%, ACS reagent
1-Methyl-2-pyrrolidinone, 99+%, for spectroscopy
1-Methyl-2-pyrrolidinone, 99.5%, Extra Dry, AcroSeal(R)
1-Methyl-2-pyrrolidinone, puriss. p.a., >=99.0% (GC)
Norleucine, 5-oxo-, DL-
Micropure ultra
N-methypyrrolidone
1-Methyl-2-pyrrolidinone, 99.5%, Extra Dry over Molecular Sieve, AcroSeal(R)
Pyrol M
N-methylpirrolidone
1methylpyrrolidinone
n-methyl pyrrolidon
n-methylbutyrolactam
N-methy pyrrolidone
N-methyl-pyrolidone
N-methyl-pyrrolidon
N-methylpyrolidinone
1-methylpyrolidinone
Microposit 2001
n-methylpyrollidinone
N-methlypyrrolidinone
N-methyl pirrolidone
N-methyl pyrollidone
N-methyl-pyrollidone
N-methylpyrrolidone-
NMP,SP Grade
1-methyl pyrrolidone
1-methyl-pyrrolidone
methyl-2-pyrrolidone
MFCD00003193
N-methy pyrrolidinone
N-methyl pyrolidinone
N-methyl-pyrolidinone
N-methyl- pyrrolidone
N-methylpyrro-lidinone
N-methylpyrroli-dinone
N-methylpyrrolidin-one
1-methyl-2pyrrolidone
1-methyl2-pyrrolidone
1methyl-2-pyrrolidone
1-methyl pyrrolidinone
1-methyl-pyrrolidinone
methylpyrrolidin-2-one
N-methy-2-pyrrolidone
N-methyl 2-pyrolidone
N-methyl-2-pyrolidone
1-methyl-2-pyrolidone
PubChem17618
3p1d
N-methyl 2-pyrrolidone
N-methyl-2-pyrollidone
1-methyl-2-pirrolidone
1-methyl-2-pyroldinone
1-methylpyrrolid-2-one
1methyl-2-pyrrolidinone
ACMC-1CKWA
n-methylpyrrolidine-2one
N-methyl-2-pyrolidinone
N-methyl-2-pyrrolidinon
N-methylpyrolidin-2-one
1-methy-2-pyrrolidinone
1-methyl-2-pyrolidinone
N-methyl 2-pyrrolidinone
N-methyl-2-pyrollidinone
N-methyl-pyrrolid-2-one
N-methylpyrollidin-2-one
1 -methyl-2-pyrrolidone
1-methyl 2-pyrrolidinone
1-methyl-2-pyrollidinone
1-methyl-pyrrolin-2-one
N-Methylpyrrolidone-(2)
NMP, N-Methylpyrrolidone
1-Methyl-pyrrolidin-2one
N-methylpyrrolidine-2-one
WLN: T5NVTJ A
N-methyl -2-pyrrolidinone
1 -methyl-2-pyrrolidinone
1-methyl -2-pyrrolidinone
1-methyl-2- pyrrolidinone
EC 212-828-1
2-Pyrrolidone, 1-methyl-
1-methyl-pyrrolidine-2-one
1-N-methyl-2-pyrrolidinone
N-methyl-pyrrolidin -2-one
KSC201Q7R
1-Methylazacyclopentane-2-one
GTPL9520
1-Methyl-2- pyrrolidin-2-one
1-Methyl-2-pyrrolidinone, 99.5%
1-Methyl-2-pyrrolidinone, anhydrous
N-Methyl-2-pyrrolidinone ACS reagent
AKOS000120930
1-Methyl-2-pyrrolidinone, BioSolv(R)
1-Methyl-2-pyrrolidinone, HPLC Grade
1-Methyl-2-pyrrolidone, Reagent, ACS
1-Methyl-2-pyrrolidinone, 99%, extra pure
1-Methyl-2-pyrrolidone (Low water content)
1-Methyl-2-pyrrolidinone, analytical standard
1-Methyl-2-pyrrolidinone, anhydrous, 99.5%
1-Methyl-2-pyrrolidinone, for HPLC, >=99%
1-Methyl-2-pyrrolidinone, for synthesis, 99%
Residual Solvent Class 2 - N-Methylpyrrolidone
1-Methyl-2-pyrrolidinone, ReagentPlus(R), 99%
Handling and Storage
NMP is classified under the Japanese Fire Services Act as a hazardous material, Class 4, Petroleums No.3 (4,000 liter quantity specified), water soluble, Hazardous Rank III.
Since NMP is hygroscopic, if moisture content is to be controlled, it is important to keep storage containers tightly closed or under a dry nitrogen atmosphere.
Since NMP is a strong degreaser, in the event of skin contact wash immediately with water.
1-Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone (NMP)
1-Methyl-5-pyrrolidinone
1-Methylazacyclopentan-2-one
1-Methylpyrrolidinone
1-Methylpyrrolidone
2-Pyrrolidinone, 1-methyl-
AgsolEx 1
Methylpyrrolidone
Microposit 2001
N-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidone
N-methyl-2-pyrrolidone
n-Methyl-2-pyrrolidone
N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone
N-Methyl-gamma-butyrolactam
N-Methylpyrrolidinone
N-methylpyrrolidone
NMP
Pharmasolve
Pyrol M
SL 1332
Translated names
1-methyl-2-pyrrolidon (da)
1-Methyl-2-pyrrolidon (de)
1-methyl-2-pyrrolidon (nl)
1-methylpyrrolidin-2-on (cs)
1-metil-2-pirolidon (hr)
1-metil-2-pirolidon (sl)
1-metil-2-pirolidonas (lt)
1-metil-2-pirolidons (lv)
1-metil-2-pirolidonă (ro)
1-metil-2-pirrolidon (hu)
1-metil-2-pirrolidon (mt)
1-metil-2-pirrolidona (es)
1-metil-2-pirrolidona (pt)
1-metil-2-pirrolidone (it)
1-metyl-2-pyrrolidon (no)
1-metyl-2-pyrrolidon (sv)
1-metylo-2-pirolidon (pl)
1-metylpyrolidín-2-ón (sk)
1-metyyli-2-pyrrolidoni (fi)
1-metüül-2-pürrolidoon (et)
1-méthyl-2-pyrrolidone (fr)
1-μεθυλο-πυρρολιδόνη-2 (el)
1-метил-2-пиролидон (bg)
<I>N</I>-metil-2-pirolidon (hr)
N-methyl-2-pyrrolidon (cs)
N-methyl-2-pyrrolidon (da)
N-Methyl-2-pyrrolidon (de)
N-methyl-2-pyrrolidon (nl)
N-metil-2-pirolidon (sl)
N-metil-2-pirolidonas (lt)
N-metil-2-pirolidons (lv)
N-metil-2-pirolidonă (ro)
N-metil-2-pirrolidon (hu)
N-metil-2-pirrolidon (mt)
N-metil-2-pirrolidona (es)
N-metil-2-pirrolidona (pt)
N-metil-2-pirrolidone (it)
N-metyl-2-pyrolidón (sk)
N-metyl-2-pyrrolidon (no)
N-metyl-2-pyrrolidon (sv)
N-metylo-2-pirolidon (pl)
N-metyyli-2-pyrrolidoni (fi)
N-metüül-2-pürrolidoon (et)
N-méthyl-2-pyrrolidone (fr)
N-μεθυλο-πυρρολιδόνη-2· (el)
N-метил-2-пиролидон (bg)
CAS names
2-Pyrrolidinone, 1-methyl-
IUPAC names
1-mehyl-2-pyrrolodone
1-Methyl 2-pyrrolidone
1-methyl 2-pyrrolidone
1-Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidon
1-Methyl-2-Pyrrolidone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-methylpyrrolidin-1-one
1-methylpyrrolidin-2-one
1-methylpyrrolidin-2-one,N-METHYLPYRROLIDONE, 1-Methyl-2-pyrrolidinone, N-METHYL-2-PYRROLIDONE
1-methylpyrrolidone
1-méthyl-2-pyrrolidone
1-O-butyl 2-O-(phenylmethyl) benzene-1,2-dicarboxylate
2-Pyrrolidinone, 1-methyl-
2-Pyrrolidone, 1-methyl
Methyl pyrrolidone
METHYL-N 2-PYRROLIDONE
n methyl 2 pyrrolidone
N-Methyl pyrolidone
N-methyl-2-pyrolidone
N-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidon
N-METHYL-2-PYRROLIDONE
N-Methyl-2-pyrrolidone
N-methyl-2-pyrrolidone
n-methyl-2-pyrrolidone
N-methyl-2-pyrrolidone
N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone
N-Methylpyrrolidone
N-Methylpyrrolidone
NMP
NMP
NMP (n-methyl-2-pyrrolidone)
Trade names
1-Methyl-2-pyrrolidinone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-5-pyrrolidinone
1-Methylazacyclopentan-2-one
1-Methylpyrrolidinone
1-Methylpyrrolidone
2-Pyrrolidinone, 1-methyl- (7CI, 8CI, 9CI)
2-Pyrrolidinone, 1-methyl-(7Cl, 8Cl, 9Cl)
M-Pyrol
N-Methyl pyrrolidone
N-methyl pyrrolidone
N-Methyl-.alpha.-pyrrolidinone
N-Methyl-.alpha.-pyrrolidone
N-Methyl-.gamma.-butyrolactam
N-Methyl-2-pyrrolidinone
N-METHYL-2-PYRROLIDONE
N-Methyl-2-pyrrolidone
N-METHYLPYROLIDONE
N-Methylpyrrolidinone
N-Methylpyrrolidon
n-methylpyrrolidon in Lube Green preparation
N-Methylpyrrolidone
NMP
POLYFLON PTFE SM-3900
Pyrol-M
